momeara

10 ms·

1.
The Hardness of 4-to-1 Games with Perfect Completeness(eccc.weizmann.ac.il)
1 points by momeara 17d ago|0 comments
2.
How Claude is accelerating protein design and analytical chemistry(anthropic.com)
1 points by momeara 1mo ago|0 comments
3.
Entire: Distributed Git for Agents(entire.io)
1 points by momeara 3mo ago|1 comments
4.
OpenEnv: An Open Source Framework for Agentic RL(huggingface.co)
1 points by momeara 4mo ago|0 comments
5.
Episteme: A New System for Science(episteme.com)
3 points by momeara 9mo ago|0 comments
6.
Reduction in Food Allergies Found After Guideline-Directed Early Peanut Exposure(ajmc.com)
1 points by momeara 1y ago|0 comments
7.
Scaling Laws Are Unreliable for Downstream Tasks: A Reality Check(arxiv.org)
1 points by momeara 1y ago|0 comments
8.
ChatGPT 5 marginalizing Gelman's measurement error model in Stan(statmodeling.stat.columbia.edu)
3 points by momeara 1y ago|0 comments
9.
Community Takes on the Future of Graph Learning(substack.com)
1 points by momeara 1y ago|0 comments
10.
LawZero Safe AI for Humanity(lawzero.org)
1 points by momeara 1y ago|0 comments
11.
SMBC Parts Ways with Hiveworks(smbc-comics.com)
171 points by momeara 2y ago|79 comments
12.
Skylight on Bluesky an atproto alternative to TikTok(bsky.app)
4 points by momeara 2y ago|0 comments
13.
An LLM promoting strategy for deep thinking(medium.com)
2 points by momeara 2y ago|0 comments
14.
XetHub is joining Hugging Face(huggingface.co)
3 points by momeara 2y ago|0 comments
15.
Temporary Internet Outage on All U-M Campuses(umich.edu)
5 points by momeara 3y ago|1 comments
16.
by momeara 3y ago
Campus IT department has declared a major incident with campus internet connectivity unavailable. This is causing problems for the first day of classes, see for example https://www.reddit.com/r/uofm/
17.
A flurry of diffusion-based models for molecular structure this year(twitter.com)
1 points by momeara 4y ago|0 comments
18.
Hybrit: Using hydrogen instead of C02 to make steel(newyorker.com)
3 points by momeara 5y ago|0 comments
19.
AlphaFold: a solution to a 50-year-old grand challenge in biology(deepmind.com)
1398 points by momeara 6y ago|660 comments
20.
by momeara 8y ago
Hey Chris--We're right now using a mix of commercial and open source software like Omega, Corina, AMSOL, and Mol2DB. Probably the slowest step is generating the partial charges for each conformer with a reasonably high quality semi-emp
21.
by momeara 8y ago
Co-author here (AMA)--A large-scale docking screen of 116M molecules takes ~1100 cpu days on our cluster, working out to about 1 mol/sec, which is very fast for virtual screening. What this doesn't account for is this requires abo
22.
by momeara 10y ago
Here is patent [1]. The key idea is to add a glucosyltransferase from Lactobacillus, which consumes simple sugars and produces complex sugars. It is not clear to me that this will be beneficial for human health. [1] https://paten
23.
by momeara 10y ago
Hi Chris, You bring up very good issues and perhaps I'm being too optimistic. I definitely agree that there isn't going to be one single mapping of sequence --> energy landscape any time soon or even ever. But I think there are
24.
by momeara 10y ago
autoencoders are unsupervised learning where CNNs are supervised. Learning the input space can be thought of as a form of regularization when training data is scarce. http://www.deeplearningbook.org/ is a wonderful resourc
25.
by momeara 10y ago
Molecular dynamics simulations can be used to answer a range of structural biology questions, but abstractly many of them can be phrased as evaluating the difference in free energy between different conformational states. In molecular dynam
26.
by momeara 10y ago
Several people have asked for background material for the workshop-- (Wallach, 2015, http://arxiv.org/pdf/1510.02855.pdf ) AtomNet: A Deep Convolutional Neural Network for Bioactivity Prediction in Structure-based Drug
27.
by momeara 10y ago
There are some, but more effort is needed. http://deepchem.io/ is trying to set up standard data sets for chemoinformatics/machine learning. ChEMBL and PubChem are the big public repositories though some care must be t
28.
by momeara 10y ago
In theory I think you are right--there should be a tower of representations from low-res/fast to high-res/slow. Though in practice it has been hard to make multi-resolution modeling work together. For example for proteins, where t
29.
by momeara 10y ago
I think one of the biggest potential for molecular autoencoders is that they can be used to generate inputs for virtual high throughput screening campaigns to predict new drugs. The idea would be to train models to predict compounds that ca
30.
Web Payments: The Architect, the Sage, and the Moral Voice(manu.sporny.org)
1 points by momeara 11y ago|0 comments

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