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melling
searching PlanetScale…
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23 ms
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361.
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by
melling
2y ago
Range of a shotgun isn’t very far?
362.
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melling
2y ago
Found this by researching the author of this TED Talk. Quite inspirational https://youtu.be/04PmEJaYKd0?si=h8VlzBLKQ0TzRdFp
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One Couple's Tireless Crusade to Stop a Genetic Killer
(wired.com)
3 points
by
melling
2y ago
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1 comments
364.
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melling
2y ago
I see where he discusses it. He said it only works for a small group and not for him. He’s mentions trying drugs that target EGFR mutations, which I believe tries to stop the blood supply to the tumor. Targeting specific protein receptors,
365.
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by
melling
2y ago
Have you discussed anything about targeted therapies? For example, how the different genetic makeup of some tumors are used to treat them. Keytruda comes to mind. https://www.keytruda.com/ Antibody drug conjugates also se
366.
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melling
2y ago
We went through all this 2 years ago with Meta. People just dump on a company all at once. https://news.ycombinator.com/item?id=33529838 Intel has a bigger problem because they are building fabs and chips but they’ve been w
367.
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melling
2y ago
8.5 hours.
368.
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melling
2y ago
Yes, it’ll take a few years for Intel’s fabs to match TSMC. $20 billion and 2-3 years per fab.
369.
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melling
2y ago
We gave them the money this year. They are building fabs. This stuff takes years. One fab can cost $20 billion.
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melling
2y ago
The Chips Act isn’t about creating jobs, we are trying to reduce our dependency on chips made in Taiwan, which produces 90% of all advanced chips. Intel is the only American company that is currently capable of addressing this problem. Othe
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melling
2y ago
I’m fine losing the dividend. Fabs are expensive.
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melling
2y ago
Sounds like they are still trying to use lanasterol: https://pubmed.ncbi.nlm.nih.gov/36484206/ I see stories about this being used for cataracts going back almost a decade. Medicine advances so slowly.
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melling
2y ago
Build a green grid. Don’t need a genius for that. The conversation for the last 25 years: “Let’s build nuclear power plants. It takes a decades. Not enough time.” Recently the twist was added: “And by the way solar and wind are cheaper” Wel
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melling
2y ago
Bringing the world to a grinding halt? Hospitals, airlines, etc I was walking into my doctor’s office and saw computers at the blue screen of death
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melling
2y ago
“If you are affected by the ongoing iCloud Private Relay outage, you can temporarily switch off the service by going to Settings > Profile > iCloud > Private Relay.” Simple enough workaround. I don’t think the two outages are compa
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melling
2y ago
I don’t know Rust but even if the Rust is just as unsafe in certain blocks, simply being translated to Rust removes a lot of corporate resistance to adopt the language. Getting people to adopt a new language can be a lot of work. I remembe
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melling
2y ago
The latest model from last fall.
378.
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melling
2y ago
Yes, it’s VO2 max. Don’t want to give my numbers but I reached low ability. I’m mainly a walker. The hills started to get difficult. I had a persistent cough that never went away after a winter cold, and shortness of breath. Now think the
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melling
2y ago
How early can it detect colon cancer? The thing is avoiding surgery requires catching the tumor when it’s a small polyp. You get chemotherapy if your tumor reaches a lymph node. I think the tests are great but the colonoscopy was a breeze
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melling
2y ago
“The test missed 17% of cancers, performance that is on par with stool-based tests.” I took a stool-based test about 6 years ago and passed. Yesterday I got back from surgery to remove a colon tumor that was discovered about 3 weeks ago. Co
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melling
2y ago
I didn’t say Trump was better for him. I just explained that many Republicans won’t currently buy electric vehicles. It should not be difficult to figure out the rest.
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melling
2y ago
I think he’s trying to save X and Tesla. EVs are political because of subsidies and X is a worthless cesspool. Politicians got way ahead of themselves by setting deadlines, like 2035, to phase out ICE vehicles, before EVs became sufficientl
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melling
2y ago
It would be easy to demonstrate. Obviously, and clearly no one wants to waste money. By the way, 100% of the time I make my observation, someone makes a similar comment as yours. Considering I’ve been making my observation for decades, I’m
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The protein Reelin keeps popping up in brains that resist aging and Alzheimer’s
(npr.org)
286 points
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melling
2y ago
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159 comments
385.
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melling
2y ago
Just an arbitrary metric. We should probably consider the cost to society then base the funding on that. For example, Americans spent $200 billion in care in 2010, and this will increase to $500 billion in 2040. Perhaps as much as $1 tri
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melling
2y ago
Maybe if millions found out a decade earlier, we’d greatly increase government funding to treat the disease. A few million more advocates for research. Seems like we currently spend about $4 billion a year. https://www.alz.org&#
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melling
2y ago
Over 90% of the most advanced chips are made in Taiwan. Military conflict in the area will massively disrupt the global economy.
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Histotripsy: Fighting Cancer with Bubbles
(youtube.com)
2 points
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melling
2y ago
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1 comments
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melling
2y ago
How have we done in the last 40 years dealing with climate change? Peak fossil fuels Real Soon Now I’d say Carl Sagan nailed it: https://youtu.be/Wp-WiNXH6hI?si=wJuFlcBbelXVfn6u
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melling
2y ago
That’s garbage you found on the Internet that simply isn’t true. Dr William Makis isn’t an oncologist either. He seems to be a radiologist. And this isn’t his only conspiracy theory. https://www.reuters.com/article/fa
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