lvs

65 ms·

571.
by lvs 10y ago
The kinds of things listed on the link have to do with project management and anecdotes about human interactions on teams that happen to be building software. You can try to tie this intellectually to more legitimately thought-out ideas, b
572.
by lvs 10y ago
The very few examples cited in the piece represent outliers. I don't have any peers who are chatting on Slack. Email is fine, and most people know that distractions (like HN) are the devil's work.
573.
by lvs 10y ago
The story begins around 18:30. After listening to these folks explain the situation of refugees and their legal status in HK, one wonders a bit why EJS decided to go there as his first stop.
574.
by lvs 10y ago
And that's true microscopically, but year-over-year the flow of money down the pipe is indeed controlled by political whims. In the Bush years, we had some grants granted by an agency that were ultimately only partially allocated by C
575.
by lvs 10y ago
That's pretty much untrue. In the US at least, the federal budget allocation passed by Congress specifies how funding is distributed across programs and to fund the implementation of initiatives specified in other acts. They not only s
576.
by lvs 10y ago
These articles sadly derive from institutional press releases that invariably oversell the underlying work. We have an unsustainable systemic problem arising from the need to convince governments filled with anti-science politicians to fund
577.
by lvs 10y ago
Speaking of intellectual dishonesty, you're putting a whole lot of words in my mouth in the process of responding to only a single one of mine. You yourself have now made accusations about my thought process that are not in evidence.
578.
by lvs 10y ago
And if there's one thing I've learned from reading your website, it's that sometimes the argument will legitimately be that the commenter is astroturfing or spewing an argument that an astroturfer would use. It seems increas
579.
by lvs 10y ago
Oh right. What about when the commenter is obviously either astroturfing or responding to the headline alone? Or perhaps you prefer to get your website brigaded?
580.
by lvs 10y ago
Surfing from link to link is very much the essential and original behavior of users on the web. A user often has very little idea what's behind the next click. I don't know what I'm getting behind the link, so a "show
581.
by lvs 10y ago
But nobody told me what was happening in the room before I walked into it. I saw nothing but a URL, or maybe I saw some text obliquely indicating what might be happening in there. I certainly didn't see the text of a contract before I
582.
by lvs 10y ago
If I pass a street musician, I haven't implicitly signed a contract to pay her for the show -- either in currency or by transferring any other valued commodity. I don't have an obligation to support her business plan, even if I e
583.
by lvs 10y ago
What? There is absolutely no criminal or civil statute nor legal principle in any American or European jurisdiction that binds users to respond to advertising in an accurate or forthright way. To have such a law on the books would be utterl
584.
by lvs 10y ago
Umm, Captain, a couple of these solder points look very fresh.
585.
by lvs 10y ago
Well, I'm quite sorry to hear that, but the paper was written for specialists, and its results are primarily interpretable by and relevant to specialists. Why exactly it made it into a press release and news articles is completely ine
586.
by lvs 10y ago
Not quite. The actual article title is far more correct than either the clickbait headline or your headline: "In Vivo Amelioration of Age-Associated Hallmarks of Progeria by Partial Reprogramming" ( my addition )
587.
by lvs 10y ago
No. That's not quite what I'm saying. There was no particularly interesting effect of inducing transient expression of the Yamanaka factors on normal mice reported in this paper. It is effectively a negative result that's
588.
by lvs 10y ago
Oh they did, in fact, but the results in WT mice were not as easy to overhype. The effects were extremely minor to nonexistent in aged wild-type animals (Fig S7 from the paper). Unfortunately, press releases and the subsequent news articl
589.
by lvs 10y ago
If you're going to use that service, I recommend using the TLS link https://sci-hub.ac
590.
by lvs 10y ago
Agreed. Just pointing out that they're going up against an established DuPont process.
591.
by lvs 10y ago
A cell is absolutely not a finite state machine, and anyone who tells you this either has no clue about biology or has no idea what a finite state machine is. A cell's "state" is governed by a highly parallel set of probabil
592.
by lvs 10y ago
So, Dupont has a production-scale microbial process for 1,3-propanediol. What is the market for malonic acid if Dupont can already go directly to 1,3-propanediol? http://www.dupont.com/products-and-services/fabrics-fibe
593.
by lvs 10y ago
I was going to say, this is an ancient and well-known optimization. I have no idea how old it is, but I would venture it's been a regular practice for at least two decades.
594.
by lvs 10y ago
Gosh. You're really not getting it. They're not losing funding because of anything specific to their research (yet). Congress passed only a single budget covering the whole government in the last 8 years! They're only keeping
595.
by lvs 10y ago
A poor guy comes here to spill his guts about potentially losing his job and all the serious science that will be stalled, and you thought his desperation was for pointers on how to be more persuasive? Yeah, the HN advice culture has reall
596.
by lvs 10y ago
Working without pay has increasingly been called "wage theft" in casual parlance, but the applicable statute depends on your jurisdiction. In the US, failing to pay a worker for completed work is a violation of the Fair Labor Stan
597.
by lvs 10y ago
It does, in fact, report around the gross profit I specified. Why don't you look at the financials [1]. I think many people in this thread, including you, don't know what the term "gross profit" means. [1] http:/
598.
by lvs 10y ago
I have not. I used the term "gross profit," which is reported on their annual income statement exactly as I suggested. You can argue whether I should have talked about their net losses, but you can't claim I've confuse
599.
by lvs 10y ago
The claim that AMD, a company with gross profit in the $1 - 2 billion range, does not have the resources to support a dedicated development team that can do a good job on upstream-able code is just farcical. That's a question of corpor
600.
by lvs 10y ago
It shouldn't require a marketing campaign to file a bug report.

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