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kyberias
searching PlanetScale…
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58 ms
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721.
▲
by
kyberias
11y ago
I'm sorry to say I laughed out loud after reading your comment, but I actually wondered about the same thing while reading the article. :) You have to admit it would be hilarious if they didn't know the size of the database or wou
722.
▲
by
kyberias
11y ago
> So - in practice - essentially, it's MS-supported (although hosted by Canonical) GNU on Windows. I don't care how it's marketed. Let me remind you that there have been numerous ports of GNU tools for the Windows operatin
723.
▲
by
kyberias
11y ago
This is not about Bash or any GNU software per se. Bash is just an example of a Linux executable that can be run on this system. One can apt-get install many more Ubuntu application binaries. Please invest some time to understand what it&#x
724.
▲
by
kyberias
11y ago
No. This is a "Windows subsystem" [1] that implements a LINUX compatible ABI for LINUX application binaries. GNU has nothing to do with it. [1] https://en.wikipedia.org/wiki/Architecture_of_Windows_NT
725.
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by
kyberias
11y ago
I'm not quite sure whether compiler optimizations could catch that. How could they? Returning false on the first zero remainder is a different algorithm.
726.
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by
kyberias
11y ago
One can kinda tell by looking at the code that the author hasn't written code professionally. At least not for very long.
727.
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by
kyberias
11y ago
Why are you enumerating your close relatives who use Linux? I can list more relatives that use Windows. What would that prove? Nothing.
728.
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by
kyberias
11y ago
This is a "Windows Subsystem" implementation. There are no open subsystem implementations and it hasn't been documented. Therefore it's a little far-fetched that they would release this as open source. Not impossible tho
729.
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by
kyberias
11y ago
Knowing the exact location in the genome, they amplified the target sequence from the DNA (using PCR) and sequenced it verifying the modification.
730.
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by
kyberias
11y ago
Ok down-voters. Do you disagree here or what?
731.
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by
kyberias
11y ago
Come on. Having actually done Westerns, there is absolutely zero chance that the "bp"=base pair in that figure is on purpose. Western blot is a protein blot and they are always measured by their molecular weight (kDa). Base pairs
732.
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by
kyberias
11y ago
That's an obvious error. The scale in the figure is kilo-daltons (for proteins). Bp scale is used in figure 1C (RNA). Perhaps they copy pasted that image when fabric... I mean polishing the images.
733.
▲
by
kyberias
11y ago
I know. I'm from Finland. Look, I'm not arguing that everyone has the ½ in their keyboards. On the contrary, most people don't. It's just funny that some people might think ½ being hard to type and some people think it&#
734.
▲
by
kyberias
11y ago
> I haven't been pulled over since. How many times did you get pulled over before the cameras and over what time period? And how long have the cameras been installed?
735.
▲
by
kyberias
11y ago
I was wondering what you're talking about but then realized that the US keyboard layout does not have the ½ symbol right there in the keyboard like we have in Europe.
736.
▲
by
kyberias
11y ago
Out of curiosity (haven't done ruby for awhile): is your line-by-line implementation safe? Is it guaranteed that the lines are identical in the output file besides the character you're replacing? I'm thinking different CR+LR
737.
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by
kyberias
11y ago
The species used here (mycoplasma) does not have a cell wall. ;) The whole point was that the new genome, when transferred to a recipient bacteria's plasma membrane with the recipient's genome removed, produces a different phenoty
738.
▲
by
kyberias
11y ago
Well, they had to have a receptive cell to bootstrap this thing, that is true. Yet, since we're talking about mycoplasma here, they don't have a cell wall (only plasma membrane) nor mitochondria (only eukaryotes have those). The n
739.
▲
by
kyberias
11y ago
You should realize that it's effectively the same thing. The bacterial genome synthesizes everything in the cell.
740.
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by
kyberias
11y ago
Oh and to answer your question, there are at least some homologs: https://d2ufo47lrtsv5s.cloudfront.net/content/sci/351/6280/a...
741.
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by
kyberias
11y ago
The original article uses these concepts interchangeably: minimal genome and minimal cell. They basically define the minimal cell as a cell with a minimal genome. E.g. "Because our minimal cell is largely lacking in biosynthesis of ami
742.
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by
kyberias
11y ago
What exactly are your criteria for a "synthetic cell"?
743.
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by
kyberias
11y ago
This article isn't really coherent or is it?
744.
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by
kyberias
11y ago
Lucky you. I also had a working VT100 some years ago. It's a nice device but rather huge. Still I hope to have it back. It was nice to see those monsters in The Big Short.
745.
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by
kyberias
11y ago
Yes, very easily. Both are compiled to .NET assemblies and can see types of each other.
746.
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by
kyberias
11y ago
What is this definition of "pure FPS" you're using? Isn't FPS simply First Person Shooter? If HL is not an FPS, I don't know what is. FPS article in wikipedia has a screenshot from the original Half Life.
747.
▲
by
kyberias
11y ago
You state that "TDD is best" in certain scenarios but fail to provide explanation. Why do you think TDD is best in the situations you enumerated? In fact, how does "database model" talk to other code? I'm pretty sur
748.
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by
kyberias
11y ago
This may be the primary reason for the multitude of protocols. Everyone thinks every existing protocol is complicated and thinks that they can implement it better. Or: https://xkcd.com/927/
749.
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by
kyberias
11y ago
I think you're wrong. I login to Office 365 with a password that has over 16 characters. I have similar length passwords in Windows networks that use NTLM. Clearly it works just fine.
750.
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by
kyberias
11y ago
How does that link prove anything?
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