ksk

43 ms·

421.
by ksk 7y ago
I don't mind donating to them, but what are the kinds of problems has folding at home has solved in recent times (~5 years)?
422.
by ksk 7y ago
There's no defending any communist regime, but I think the more likely explanation is that China had no reason to suspect that it was anything other than flu for a long time. They made it worse by trying to "manage" the panic
423.
by ksk 7y ago
I think that is a slippery slope. Once it was known, other countries did nothing to stop the spread either by allowing free travel rather than going into a lock-down mode. Each country put their economy ahead of the well-being of their citi
424.
by ksk 7y ago
Just to add another anecdote to yours, I've had none of your 'countless problems'. The W10 machine that I'm typing this on hasn't been rebooted in 8-9 months (bribed IT into putting my box in a no-update GPO :D). It
425.
by ksk 7y ago
That's nice but it's hard to beat - typewriter as a gift in ones teens to flying in metal cages, to going to the moon, to VR headsets. I remember reading opinion polls from people who saw this rapid rate of progress in the 60s 70s
426.
by ksk 7y ago
Has it really shown that, or is it just survivorship bias? How many open source projects have failed despite having all those attributes?
427.
by ksk 7y ago
They're already using MD simulation in certain areas of drug discovery (computer aided drug design). Naturally, as you mentioned we're compute-limited so the models are simpler and the questions we ask of it are also 'simple&
428.
by ksk 7y ago
Might be useful to cluster the papers into various topics. For e.g. a person interested in drug discovery needs a different (biochem biased) set of papers than one doing vaccine development (immunology biased). *(caveat obvious overlaps)
429.
by ksk 7y ago
>I am worried about this: Long hours means stress and stress means susceptibility to illness. Is this a 0.1% chance or a 90% chance? One matters, the other doesn't :)
430.
by ksk 7y ago
>Most people who celebrate how much of a "hard worker" and wear 50-60 regular work weeks like badges of honor that aren't being compensated extra drank the corporate culture koolaid their HR/HR management offered them
431.
by ksk 7y ago
What does the data say? What products are people buying as of now on Amazon?
432.
by ksk 7y ago
Please read the sources you linked to. The problem is the disease model and how the disease presents itself, how and where the samples are taken, etc. The PCR test is not what is the problem. Its the gold standard. We use it daily at our co
433.
by ksk 7y ago
>I think this is similar to what everybody else is doing -- using a thermocycler to run PCR What method do you propose without a thermocycler?
434.
by ksk 7y ago
Um, what? What is inaccurate about the PCR?
435.
by ksk 7y ago
Who is going to supply you the primer for that kind of volume? :)
436.
by ksk 7y ago
I wish they had released more details on how they grew it. I wonder if they used micro-carriers...
437.
by ksk 7y ago
What manufacturing advantages would a city in 1918 have, to deal with today's situation for example?
438.
by ksk 7y ago
A plasmid does not 'integrate into the host genome'. The entire genome for human cells is stored inside the nucleus packaged as chromosomes. The plasmid exists outside of this, and just hijacks our replication machinery.
439.
by ksk 7y ago
Sorry, that's just an impermeable wall of text to me. I'd love to know from someone who groks this, the specific wording in the bill that would address the ER costs issue, and where the current legislation fails. Basically I'
440.
by ksk 7y ago
Is there anyone doing work on analyzing current legislation and providing alternate wording to fix the issue?
441.
by ksk 7y ago
'Banning' things you don't personally like is not a great tactic to convince people. Other technologies should keep making things easier for the C folks to migrate to...
442.
by ksk 7y ago
Well if they would have written Windows in a dynamic language 26 years ago, nobody would be using it, and the cost would be zero.. :P
443.
by ksk 7y ago
Why limit developers freedom? If it were so simple with no negative consequences, people would be using Rust already.
444.
by ksk 7y ago
>My comments are about how a lot of people tend to put the person ( + credentials) before the soundness of their arguments. Ok fair enough. So what is the argument that you feel was not sound? And who said that they believed the argument
445.
by ksk 7y ago
And who determines what a "nice explanation" is, and what is or isn't backed by science? Another expert that you then have to trust? When dealing with technical topics that require deep study, unless you're some kind of
446.
by ksk 7y ago
>Most droplet born viruses are very contagious (e.g. efficiently infect a target). Is that your own co-relation? For e.g. Influenza Type B versus Influenza type C. Type C is not as contagious and the seasonal flu vaccine does not cover i
447.
by ksk 7y ago
The virus can mutate and the vaccine will still work if the mutation doesn't cause a change to the epitope. (caveat other technical issues)
448.
by ksk 7y ago
Yeah, I should have known better than to say that given that I work in the vaccine field, but not as a scientist. I guess I deserved that :P
449.
by ksk 7y ago
Well, to be fair, its not meant to be a textbook or a journal article where being super explicit matters much more. It's a fun article for laypeople like us.
450.
by ksk 7y ago
The R0 of the disease is more of a statistical problem. IMHO the question is actually not straightforward. To answer that question implies that the data that we have is representative, or that the current disease model is accurate. The numb

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