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koeng
searching PlanetScale…
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20 ms
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211.
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by
koeng
5y ago
iSH is great on the iphone. Full alpine linux virtualized with x86 (and still somehow fast). Highly recommend
212.
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by
koeng
5y ago
Biohacking/biotech is an interesting example, since you can scale down to individual biohackers or up to farms (in which those farms very clearly have manufacturing/process that is hard to replicate). However, biology also has the
213.
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by
koeng
5y ago
I walked along Huntington Beach’s beach today to checkout what happened. Although the cleanup workers did a great job, there were still puddles of oil on the sand, and you could definitely smell it in the air. The puddles were much clumpier
214.
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by
koeng
5y ago
This is extremely cool and I will be testing it out. I’m building large systems for handling biological data, and have wanted to use prolog for that use, but couldn’t fit all of my data in RAM. This could help me a bunch.
215.
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koeng
5y ago
How do you mirror the gemlog to HTTP? I've found a lot of methods for like active proxies, but I'd really like something that could create a static site from my gem text files.
216.
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by
koeng
5y ago
Check out Poly [1] for a great Golang library specifically built for forward engineering and synthetic biology: [1] https://github.com/TimothyStiles/poly/issues
217.
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by
koeng
5y ago
Does anyone know when starlink is going to be available for RVs or campers? I'd love to bring the internet while I camp around California, but right now there are range restrictions.
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by
koeng
5y ago
I'd recommend iGEM, Synbiobeta, and the Biosummit (when the conferences are in person). Synbiobeta for industry, biosummit for the hacker vibes, and iGEM because almost every synthetic biologist passes through iGEM (plus can meet a bun
219.
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by
koeng
5y ago
I got a virology textbook in 6th grade that I fell in love with, and then started doing at home biotech stuffs with a GFP transformation kit from BioRad that my teacher let me take home in 7th grade. Bit unconventional! For an amateur, I&#x
220.
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by
koeng
5y ago
I’m a major contributor to a synbio software package https://github.com/TimothyStiles/poly and I also do quite a lot of robotics in the space (have a full DNA foundry running in my house, that took a lot of software).
221.
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by
koeng
5y ago
How about Golang in this case? AFAIK there haven't been any breaking changes yet.
222.
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by
koeng
5y ago
We're trying to build the best synthetic biology library out there - https://github.com/TimothyStiles/poly
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by
koeng
5y ago
Original paper link - https://doi.org/10.1038/s41586-021-03774-y From a synthetic biologists perspective: Very cool work! It doesn't get us that much closer to fully synthetic life (ie, self replicating), but can
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by
koeng
5y ago
As an aside - for anyone working with databases in Go, check out https://pkg.go.dev/modernc.org/sqlite It allows drop in replacement of SQLite that is in pure Go - no CGO or anything required for compilation, while sti
225.
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by
koeng
5y ago
For anyone interested in what the tech is (very hard to find on their website) here is a quote from a techcrunch article https://techcrunch.com/2019/11/04/battery-tech-startup-sila-... "Sila Nanotechnolo
226.
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by
koeng
5y ago
“ First, it seems improbable that in the narrow area of expert performance we find that practice dominates, whereas in everything else, we find that genetic factors have an equally large (if not greater) effect on outcomes. (This latter bit
227.
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by
koeng
5y ago
Here is the paper link - https://doi.org/10.1016/j.molcel.2021.08.008 They did a lot of hard work to get there! A few years we synthesized some prokaryotic argonaute proteins for their lab. Bet they were considering th
228.
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by
koeng
5y ago
Avoidance of link rot should probably be done with the paper's DOI number - https://dx.doi.org/10.2139/ssrn.3912074
229.
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by
koeng
5y ago
Very nice! Any known limitations on number of torrents?
230.
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by
koeng
5y ago
Basic string manipulation, JSON encoding, file reading/writing, some type of hashing/checksum, and an HTTP client/server. Those things I’ve really appreciated about Go lately as I get it to control robots (controlling them ov
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by
koeng
5y ago
One thing that I’m quite bummed out with Zig is the lack of a good http server/client implementation in the standard library. Golang’s std implementation on this is really quite nice.
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by
koeng
5y ago
I've really enjoyed developing on K3s, would recommend.
233.
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by
koeng
5y ago
They could also use normal editing with PCR since the genomes are small. Also CRISPRs are in tons of organisms (I’ve amplified it from yogurt), so the box is already out there.
234.
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by
koeng
5y ago
I have experience in DIY genetic engineering (have run a DIY home genetic engineering lab for almost 10 years now https://www.nytimes.com/2018/05/14/science/biohackers-gene-e... ) What you can do and w
235.
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by
koeng
5y ago
I wasn’t talking about mutation rates. Influenza has mini-chromosomes which it can swap between strains, leading to more variants since they can swap those mini-chromosomes. SARS-CoV-2 has a single linear genome - only recombination on the
236.
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by
koeng
5y ago
I'd say the achilles heel is most likely in the genomic structure, which unlike influenza, is less likely to recombine.
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by
koeng
5y ago
Democratization works both ways. The more people who can build, the more people who can cure. From COVID19, at least, I think we need more people who can cure. Also I can’t really imagine a biological mechanism that can lead to human extinc
238.
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by
koeng
6y ago
Unfortunately this doesn’t work well in much of California due to argentine ants having a much more decentralized structure with a single massive mega colony (there are thousands/millions of queens in a massive connected super colony).
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by
koeng
6y ago
If you burst open the cells and extract all the goop inside, you can use that goop to express proteins. For certain organisms, like E.coli, this works quite well, and you can get a significant amount of protein. For others, like JCVI-Syn3,
240.
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by
koeng
6y ago
https://vizbi.org/Posters/Images/2021/vB26.png They're working towards it :)
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