kmckiern

7 ms·

1.
by kmckiern 1y ago
fun!
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Show HN: O3 beats Sonnet 4 at coding (in our codebase, wrt our preferences)
2 points by kmckiern 1y ago|0 comments
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by kmckiern 1y ago
> I can't see what is what "the economy" has given to us in return. Reductions in extreme poverty, increases life expectancy, improved access to education and healthcare.
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by kmckiern 1y ago
Data is useful! But it seems like (I am not an economist) the incentive structures around these offices are failing. Maybe the benefits need to be more immediate / obvious / visceral.
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by kmckiern 2y ago
Interesting - I've heard this anecdotally. Curious if you know of any resources that look at this in more detail?
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by kmckiern 2y ago
https://arxiv.org/abs/2406.11717 https://huggingface.co/blog/mlabonne/abliteration
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Light-based photocatalytic system can break down PFAS at room temperature(phys.org)
21 points by kmckiern 2y ago|1 comments
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by kmckiern 2y ago
https://cdn.openai.com/o1-system-card-20240917.pdf Check out the "CoT Deception Monitoring" section. In 0.38% of cases, o1's CoT shows that it knows it's providing incorrect information. Going beyond hal
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Refusals (LLM Leaderboard)(mandoline.ai)
2 points by kmckiern 2y ago|0 comments
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by kmckiern 2y ago
While GDP is growing, there has been a long-term decline in wages as % of GDP: https://fred.stlouisfed.org/graph/?g=2Xa The median worker's day-to-day perceived quality of life may be more aligned with this downwa
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by kmckiern 2y ago
First of all - very cool that they were able to image this and work out the mechanical mechanism in such detail. Second - the rupture event looks so violent but iiuc it’s actually highly controlled: - the rupture site is thinned early in th
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Comparing Refusal Behavior Across Top Language Models(mandoline.ai)
2 points by kmckiern 2y ago|0 comments
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Show HN: Mandoline – Custom LLM Evaluations for Real-World Use Cases(mandoline.ai)
2 points by kmckiern 2y ago|0 comments
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by kmckiern 5y ago
Since boundaries can be very helpful: could many lower level theories ‘emerge’ to classical physics?
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by kmckiern 5y ago
"the biggest problems in drug development are not really solved by having faster access to protein structures ... we have far bigger issues with target selection (does this idea of ours really do anything against the disease, in the en
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AlphaFold Excitement(science.org)
1 points by kmckiern 5y ago|1 comments
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by kmckiern 5y ago
Who is your ideal user? Do you think this person frequents ProductHunt? That's your answer. My experience is that the main users of PH are those launching a product. I'll also add: after my PH launch, I experienced a lot of email
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by kmckiern 5y ago
It's hard but people do it! This is the field of "protein engineering".
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by kmckiern 5y ago
Where there isn't an available crystal structure, Alphafold can be used to create initial structures for simulation via folding@home, replacing older homology modeling techniques. Source: former folding@home researcher.
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Rate Your Risk Quiz(statslab.cam.ac.uk)
2 points by kmckiern 5y ago|0 comments
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by kmckiern 5y ago
SF Mono!
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Fabbrica: A sans serif typeface with a utilitarian aesthetic(cinetype.com)
135 points by kmckiern 6y ago|82 comments
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by kmckiern 6y ago
Super cool, congrats to the team! I can't count how many times I've had to open the merging section of the pandas docs. Great library but I find a lot of it unintuitive and hard to commit to memory.
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by kmckiern 6y ago
That’s great feedback, thank you! We believe we’re differentiated in being both social and prosumer. E.g. we give advanced risk and performance metrics on every index, and are building a lot in-app for folks to collaborate.
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by kmckiern 6y ago
Yes agreed! Right now users can write a short description but we want to expand on this. Thanks for your feedback.
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by kmckiern 6y ago
Anyone can invest in any public index. We do have private indexes too (this is a premium feature, where we charge a subscription), wherein only folks you share your index with can view and invest. You can also "nest" others'
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by kmckiern 6y ago
Thank you! "For hackers" is because it's very DIY, at least at the moment, e.g. if you like to fiddle with different ideas. "Like code" is because we've used a lot of our favorite github features in building th
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by kmckiern 6y ago
We have a handful of users with this exact use case!
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by kmckiern 6y ago
Paul Graham wrote about this: http://www.paulgraham.com/startuplessons.html
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by kmckiern 6y ago
Thank you! Indeed, there's a lot of opportunity cost in building and maintaining the tools. If you're interested in investing, you probably want to spend your time on investing rather than migrating databases all of the time etc.

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