klmr

11 ms·

61.
by klmr 6y ago
> A pet theory of mine is that they simply were out-competed. This is the (by far!) most prevalent expert opinion.
62.
by klmr 6y ago
You seem to be basing your opinion on two main assumptions, of which one is unknown and one is untrue: > the original biocatalysts a.k.a. enzymes were RNA molecules unlike anything that exists today. Why “unlike anything that exists to
63.
by klmr 6y ago
As a point of minor historic curiosity, the pipe operator in R actually predates dplyr and was invented independently multiple times by various people who noticed that the Unix model translates well to data transformations in R (F# also has
64.
by klmr 6y ago
I’m also not sure how well the contents translate to German. After all, Germany has not only compulsory education but the “allgemeine Schulpflicht” (i.e. compulsory school attendance), meaning homeschooling is, for the most part, strictly
65.
by klmr 7y ago
I’m assuming that the comment I was replying to was using the perceived “tidiness” of the picture as the sole evidence for their claim that it looks engineered. What else could they mean? — Of course you’re right that an engineered virion w
66.
by klmr 7y ago
There’s no surprise, zoonotic viruses are well known. That said, viruses are usually highly adapted to a specific host. Jumping host species isn’t trivial, and the mechanisms for how this happens are worth exploring.
67.
by klmr 7y ago
Nothing in this image looks engineered. In fact, this is an illustration of a comparatively messy virus particle. Other viruses look a lot more regular and “artificial”. Check out the pictures (including actual SEM pictures) on https:&#x2F
68.
by klmr 7y ago
The language is too weak to express it safely . CoW on mutable strings in C and C++ by necessity implies safety (or drastically performance-degrading) tradeoffs. By contrast, `jv` types are immutable so they can presumably implement CoW wi
69.
by klmr 7y ago
> Multi-million grants are common in academia. Not in the way you explain. Multi-million dollar grants are usually awarded over multiple years, and pay for multiple researchers’ salaries, as well as other resources, some of which are e
70.
by klmr 7y ago
Children learn by imitation. That , and not the fear that the child might run after you (?!), is the reason why it’s frowned upon to cross red lights in front of children.
71.
by klmr 7y ago
> frustrating and illogical! That’s certainly a matter of opinion (and as a German currently living in the UK I disagree): Having separate green light for pedestrians means that the average waiting time is much longer (both for cars an
72.
by klmr 7y ago
Also France.
73.
by klmr 7y ago
Drag&drop maybe (although I’ve dropped more things accidentally on the wrong target than I’d care to admit). Copy&paste? Often accidental.
74.
by klmr 7y ago
You’re right, of course. I had completely forgotten that.
75.
by klmr 7y ago
> tail recursion in Python using the Y combinator Small correction: this answer does not use the Y combinator to optimise tail recursion in Python (and this would be impossible). Instead, it modifies the Y combinator to do this, by
76.
by klmr 7y ago
(nonsense deleted)
77.
by klmr 7y ago
I appreciate your comment and your experience. And I agree: integration tests tend to be time consuming to run. At work we actually had similar issues (and many of our integration tests need to exercise cloud APIs) before a rewrite that mad
78.
by klmr 7y ago
> [in C++] it can actually be fairly challenging to do unit tests without mocks Yes, but you can write integration tests instead. There’s no rule that says that unit testing must cover every aspect of the software. Unit test those unit
79.
by klmr 7y ago
> Writing testable code is not "damage" Correct, but you can go a long way in writing testable code without requiring mock implementations. While I don’t deny the usefulness of mock testing, it comes at a steep cost (= vast
80.
by klmr 7y ago
It’s funny that you cite only the ayurvedic name, since the scientific name, diabetes mellitus , has the exact same etymology: “mellite” is Latin and translates to “sweetened [with honey]”, and the disease was thus named in 1675 because
81.
by klmr 7y ago
Drawing a single diagram will be faster, true. But adding even a single new node which requires re-layouting the whole thing to make space would require you to redraw the whole diagram, whereas in Graphviz/DOT it’s literally just addin
82.
by klmr 7y ago
Brandenburg and Berlin are fundamentally unrelated, they’re two completely distinct, and politically and (largely) economically independent regions. While Berlin is geographically within Brandenburg, they couldn’t be more different, and t
83.
by klmr 7y ago
Interesting, thanks for the correction. … if I ever knew this I forgot it.
84.
by klmr 7y ago
That’s exactly what happened, and no, I didn’t lose my status. There are internal metrics for showing individual moderators’ activity but — at least while I was a moderator —these were purely FYI, and not used to enforce activity. I eventua
85.
by klmr 7y ago
> nobody was advocating misgendering That isn’t true. Monica didn’t advocate misgendering but there was at least one other moderator (since resigned) who did. I’m not sure if that’s what iron1003 was referring to since it wasn’t as w
86.
by klmr 7y ago
> On Stack Overflow, the moderators really are working directly on improving the site's content. They're practically unpaid editors. So do non-moderators. In fact, there are some users who do more work towards improving the s
87.
by klmr 7y ago
> That's not true for moderators: they have specific tasks they must complete, and they must continue to be active, or they lose their moderation status. That’s not correct: especially on the small sites, it’s acceptable for moder
88.
by klmr 7y ago
So, to clarify, in that comment by me, “guided” (and, in fact, my whole comment) definitely implies “directional”. But let’s not get hung up on this one word. The comment was about encoding learned experience in the DNA of gametes (i.e. Lam
89.
by klmr 7y ago
> [Being an expert] doesn't mean that you're not making a misstep here. That’s correct, but we’re not discussing the cutting edge here but relative basics. I’m clearly not articulating myself well but I can assure you that th
90.
by klmr 7y ago
Iʼm aware of how evolution works, thanks. I do have a PhD in genetics after all. But this isnʼt what you were talking about here, which is the hypothetical existence of a biological mechanism enacting differential, directional selection.

More ›