klmr

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331.
by klmr 8y ago
Not an ancient Egyptian tomb, no.
332.
by klmr 8y ago
How is a similar (not even identical) name a “name conflict”? Even if both were named “cheat”, one is a Unix command, the other is a URL that you access via HTTP (in other words, they occupy different, non-conflicting namespace). What’s m
333.
by klmr 8y ago
> [mammals] and chordata in general are highly diverse Yes but we’re speaking of adaptability on the level of species . And the more specialised a species is to an environment, the higher its investment (in terms of some vague “evolvabi
334.
by klmr 8y ago
To start off, yes, the trait needs to provide a reproductive fitness benefit. The problem is runaway sexual selection [1]. The textbook example of that being the peacock plumage, which is subject to strong sexual selection, yet is a detrime
335.
by klmr 8y ago
I’m puzzled by your interpretation: One of the first things the article does is acknowledge the usefulness of sexual dimorphism, and backs it up with references to research. I agree with you that the research on ostracods is unlikely to gen
336.
by klmr 8y ago
Chrome’s address bar also searches bookmarks (along with history) when you type: bookmark items are prefixed by a star in the dropdown.
337.
by klmr 8y ago
I’m pretty sure Anders’ salary at Microsoft qualifies him being called rich.
338.
by klmr 8y ago
I very much share the sentiment and I’ve been using Vim (recently Neovim) pretty much exclusively for the last ~20 years. But VS Code “just works” to such an extent that I’m seriously tempted to use it.
339.
by klmr 8y ago
And if OP is interested in improving the typography, a trivial, side-effect free improvement that’s currently missing would be to replace dashes and quotation marks by their “proper” glyphs, and using non-breaking whitespace where appropria
340.
by klmr 8y ago
Honestly, the custom layouting on this website is cute but I wish the author would ship proper HTML code instead and accept the slightly (if that!) inferior layouting of the browser engine. At the moment the layouting als breaks the expec
341.
by klmr 8y ago
> You'll have to justify this: "Prior studies were riddled with inadequacies in controlling for confounders and outright methodological errors." That topic has filled whole blog posts. But in a nutshell, no previous study
342.
by klmr 8y ago
> You don't have that guarantee with interfaces either True, but you can give the interfaces/contracts proper names (or namespaces). To use the example in the parent comment, `Array` and `Keyboard` wouldn’t implement the same c
343.
by klmr 8y ago
> there was a large study showing the opposite on HN a while back. Yes, sorry: I didn’t mean to ignore that part of your answer but the research I’ve linked to essentially supersedes everything else in that area. Prior studies were riddl
344.
by klmr 8y ago
> typing errors aren't a great source of errors. That’s not true. On the contrary, typing accounts for a substantial fraction of all errors (and refactoring could transform even more logic errors into catchable type errors). The bes
345.
by klmr 8y ago
Sorbet appears to be a language extension rather than a library, similar to TypeScript or Flow in the JavaScript ecosystem. I’m guessing that one of their goals was ease of use for type annotations. I’ve had a quick look at RDL and while I
346.
by klmr 8y ago
> I like Ruby in part because it's strongly typed but I don't have to lose time writing types. That’s why type inference exists. Static typing doesn’t imply annotating everything manually with types. Granted, most static ty
347.
by klmr 8y ago
Could you give some details? I’m no longer intimately involved with either technology but from what I can see Microsoft has been doing a lot of good things in .NET Core and with TypeScript. What are the shenanigans you’re referring to?
348.
by klmr 8y ago
Suit yourself. But as mentioned elsewhere, the equivalent of GDPR has been law in Germany for over a decade, and small businesses have had no problem complying.
349.
by klmr 8y ago
> I can’t help but wonder if this is the root of much of the misguided interest in epigenetics. In a word: yes. Even within the field this causes confusion (researchers of course know the distinction in principle, but the term “inherit
350.
by klmr 8y ago
I keep telling you, it has been tested, and disproved — countless times. That’s what “contradicted by Dirac’s equation” means. If you insist on ignoring that evidence then, yes, you are absolutely ignoring physics.
351.
by klmr 8y ago
What you’re saying is just paraphrase for “ignore physics”. If you’re willing to do that, then why bother with quantum mechanics etc at all?
352.
by klmr 8y ago
That’s correct but you’re (understandably) confusing “epigenetic inheritance” with “ trans-generational epigenetic inheritance”. The first (i.e. epigenetic inheritance, particularly via DNA methylation) is a ubiquitous biological process b
353.
by klmr 8y ago
That’s irrelevant. These terms don’t mean anything in isolation. You just picked the two terms on the Wikipedia page on Bell’s theorem that allow you to escape the restrictions of quantum nondeterminism. But you missed the fact that they do
354.
by klmr 8y ago
> You say nanobes aren't life, but then you say you don't know? Pick one. No, ben_w said that they “aren’t ‘determined to have life’”. That’s a very different statement. But I’ll go out and say it: they aren’t life. Nobody is t
355.
by klmr 8y ago
The article also states why that omission is irrelevant. > And the article makes the mistake of assuming that life force is the physical driving energy No, it’s simply a tautology: if it interacts with physical entities, it’s physical. E
356.
by klmr 8y ago
> some people generally have low stomach acid Not to the extent that you (and many others) believe. The stomach is always very acidic (pH 1–3), and this acidity is tightly regulated. Contrary to what you’ve said, the pH is raised (and
357.
by klmr 8y ago
I mean, you’re totally right to be sceptical of heritable learned experience but your description is off: Firstly, what do these 16 bits refer to (a single nucleobase encodes 2 bits of information and there are easily > 8 mutations from
358.
by klmr 8y ago
Yes, by raising pups with surrogate parents. However, the study was criticised for other reasons (lack of statistical power, no explanatory mechanism) and, in the intervening years, nobody has successfully replicated this experiment.
359.
by klmr 8y ago
That’s probably the next step (the authors raise the question of the identity of the implicated RNA). Transcriptome profiling (which this is) has become extremely routine recently. In fact, it’s highly unorthodox that this analysis isn’t al
360.
by klmr 8y ago
Elizabeth Rosner isn’t a biologist, and (unintentionally, I’m sure) misrepresents the research. The majority view in the field of epigenetics is that trans-generational epigenetic inheritance of things like trauma currently lacks compelling

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