klevertree

8 ms·

31.
My terrible plan for reducing opioid deaths(trevorklee.com)
2 points by klevertree 5y ago|1 comments
32.
Aging researchers should try reversing graying first(trevorklee.com)
1 points by klevertree 5y ago|0 comments
33.
Charismatic Megadiseases(trevorklee.com)
1 points by klevertree 5y ago|0 comments
34.
Why did they give antidepressants to Covid patients?(trevorklee.com)
2 points by klevertree 5y ago|0 comments
35.
by klevertree 5y ago
To add to what everyone else said: it's not just an immunosuppressant, it's an immunosuppressant with unpredictable, severe side effects. It's really interesting, and I hope to reformulate it to make it possible for healthy p
36.
by klevertree 5y ago
I thought it'd be too much in the weeds. The UTexas paper goes into their prescribing data and comes out with the conclusion that calcineurin inhibitors are the only common factor in their patients who don't get dementia. Rapamyci
37.
Organ transplant patients may not get dementia(trevorklee.com)
290 points by klevertree 5y ago|190 comments
38.
Why isn't being obese worse for your health?(trevorklee.com)
3 points by klevertree 5y ago|0 comments
39.
A lesser known mechanism for alcohol tolerance(trevorklee.com)
191 points by klevertree 5y ago|144 comments
40.
by klevertree 5y ago
That's not muscular dystrophy. That's a motor neuron disease.
41.
by klevertree 5y ago
Sorry, didn't mean that it was obvious scientifically. I meant obvious in terms of pharmaceutical progress. They built a mouse model to mimic muscular dystrophy and cured the mouse model of muscular dystrophy, which is why they felt co
42.
by klevertree 5y ago
In this analogy, I meant to indicate all the wooden beams were rotten to the core, in the same way that muscles die in Duchenne muscular dystrophy. Quadrupling up the beams just means that you've spent a lot more resources on something
43.
Why can't we just give steroids to people with muscular dystrophy?(trevorklee.com)
153 points by klevertree 5y ago|121 comments
44.
Difficult math is about recognizing patterns(get21stnight.com)
116 points by klevertree 5y ago|59 comments
45.
How to spot a good fake ID(trevorklee.com)
243 points by klevertree 5y ago|305 comments
46.
by klevertree 5y ago
Highway Pharmaceuticals | looking for cofounder with PhD or Masters and love of the tedious parts of science| remote | Highway Pharmaceuticals is developing drugs for autoimmune conditions that aren't treated well by biologics. We curr
47.
by klevertree 5y ago
No, that substitution helps, but it doesn't solve the problem. You're still introducing foreign mRNA into the body, and the body still has millions of years of evolution telling it that foreign mRNA = invader .
48.
by klevertree 5y ago
I wrote a long essay about the same topic and came to similar conclusions as Derek Lowe: https://trevorklee.com/are-mrna-therapies-the-future-of-phar... One thing that I'd like to emphasize is how unbelievably tiny mRN
49.
by klevertree 5y ago
Huh, not entirely sure what you mean. When you say readily available and updateable, what are you hoping to accomplish?
50.
by klevertree 5y ago
Anki has a lot of features and it's been around forever. It's tough to keep something like that smooth and sleek. But yeah, my original impetus for creating this was loving the idea of Anki, but having a really hard time sticking
51.
by klevertree 5y ago
Nope! A lot of features Anki doesn't have. Try out the demo account and let me know what you think.
52.
by klevertree 5y ago
Well, it's an alternative for people who are looking for interesting, useful flashcard apps and found Anki limited or hard to use. Would you say Windows isn't an alternative for Linux?
53.
by klevertree 5y ago
It's not OSS, no. OSS is a tough business model for small SAAS. And there are alternatives, but none of them work quite as well for the intended use case. It's possible to hack Anki for most of the functionality of 21st Night, but
54.
by klevertree 5y ago
Oh man, you are correct. Shoot. I don't know how I did that.
55.
by klevertree 5y ago
Thanks! Yeah, Remnote is also really cool and a great product.
56.
by klevertree 5y ago
Not, not just tagging. Try creating a note, then highlighting a phrase from that note. You'll see that you have the ability to create a card from that phrase, which will then be attached to that note. The next time you pull up that not
57.
by klevertree 5y ago
Cloud storage. I didn't expect people to use this for confidential knowledge, to be honest.
58.
Show HN: Anki alternative with integrated notes and import/export(get21stnight.com)
123 points by klevertree 5y ago|128 comments
59.
Why bigger species live longer and what we can learn from it(trevorklee.com)
1 points by klevertree 5y ago|0 comments
60.
Are mRNA therapies the future of pharmaceuticals?(trevorklee.com)
3 points by klevertree 5y ago|0 comments

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