kanzure

14 ms·

121.
by kanzure 7y ago
> I have to tell stories too because if I don't.... Sounds like reputation afforded to academia (professors) might be inappropriate. Besides, science shouldn't be judged by reputation but by fact and result. The idea of evaluat
122.
by kanzure 7y ago
Then this comment isn't for you, but rather other HN readers. If you believe in the importance of science, and if you're a software engineer at FAAAANG, then you can afford a 75+45 TB (scihub+libgen) hard drive array. If you are m
123.
by kanzure 7y ago
... Have you read it? You might find that it's not quite the cautionary tale against genetic enhancement that you might think.... "The use and misuse of Brave New World in the CRISPR debate" https://www.liebertpub.
124.
by kanzure 7y ago
Here's a transcript of that talk: https://diyhpl.us/wiki/transcripts/sf-bitcoin-meetup/2015-02...
125.
by kanzure 7y ago
You can play around with Shamir's secret sharing here: http://passguardian.com/
126.
by kanzure 7y ago
I recently typed a transcript of a talk about verifiable delay functions: http://diyhpl.us/wiki/transcripts/verifiable-delay-functions...
127.
by kanzure 7y ago
Well, the one that says medical procedures are only practiced on people.... and that embryo editing is not editing a person. But anyway, we really do need a way for people to let themselves opt out of the FDA's regulatory regime for al
128.
by kanzure 7y ago
> Nothing is stopping decentralized decision making, you just need to market whatever non-effective but safe remedy you're selling as a food supplement a tea or whatever. You just can't advertise that it's a drug. Unfortun
129.
by kanzure 7y ago
I've been referencing this lately: https://github.com/pditommaso/awesome-pipeline
130.
by kanzure 8y ago
I typed a transcript http://diyhpl.us/wiki/transcripts/human-genome-editing-summi...
131.
by kanzure 8y ago
Here's a transcript of Jiankui He's talk in Hong Kong on his human embryo editing project: http://diyhpl.us/wiki/transcripts/human-genome-editing-summi...
132.
Transcript: Human Embryo Editing (Jiankui He)(diyhpl.us)
3 points by kanzure 8y ago|0 comments
133.
by kanzure 8y ago
Your method of modifying human height is naive because it assumes that your genetic modification technique to increase height would need to modify or even know about height alleles. edit: We last talked October 2015, hi.
134.
by kanzure 8y ago
I have a few thoughts about privacy for you. Don't use academia.edu or researchgate. It's a big story waiting to get out. There's absolutely no privacy on these sites and they track everything. I get an email notification fro
135.
by kanzure 8y ago
Academic publishers also insert IP addresses and other deanonymizing information (about the user) into PDFs of academic papers, which should be removed. https://github.com/kanzure/pdfparanoia
136.
by kanzure 8y ago
"Exploring protein orthogonality in immune space: a case study with AAV and Cas9 orthologs" https://www.biorxiv.org/content/early/2018/01/10/245985
137.
by kanzure 8y ago
My personal preference is an inflatable sun shield method like these 10,000 kilometer-wide objects: "Self-deployed, extremely large low mass space structures" http://diyhpl.us/~bryan/papers2/space/Se
138.
by kanzure 8y ago
I wouldn't expect the number of human autopsies to be more than a few million over the entire history of the human species. Nobody looks at human brains. It's a huge problem.
139.
by kanzure 8y ago
My understanding is that Microsoft does not auto-publish+sell third-party libraries in a package repository. So the difference is basically the distinction made in the old cathedral/bazaar analogies.
140.
by kanzure 8y ago
I've been wondering whether a for-pay alternative to the open-source ecosystem could be developed. The problem seems to be that open-source gratis software contributes nearly zero friction to a company building out its tech, so any alt
141.
by kanzure 8y ago
DNSSEC signing ceremony is significantly more transparent and public :-) https://www.iana.org/dnssec/ceremonies
142.
by kanzure 8y ago
> I find it fascinating that we have not witnessed self reproduction and evolution in a simulated world as of now "The evolution of self-replicating computer organisms" (1996) http://diyhpl.us/~bryan/papers
143.
by kanzure 8y ago
you can remove that https://github.com/kanzure/pdfparanoia
144.
by kanzure 8y ago
What are you talking about? "I'll show up with hard drives and whatever I have to do. I'll rent the damn Amazon snowball truck if I have to."
145.
by kanzure 8y ago
Does anyone have a complete copy? The seeds are very slow. I know someone willing to pay for this data. Shoot me an email.
146.
by kanzure 8y ago
Autopsy report already says ketamine overdose. edit: source is the-scientist.com
147.
by kanzure 8y ago
> Hashing the data that's added to the archive and then putting the hash in the blockchain would reasonably prove the data in the archive hasn't been modified at a later date. Here have yourself a timestamp https://p
148.
by kanzure 9y ago
Yeah, it would certainly help to use a method like expansion microscopy, sort of like if Nectome were to subcontract some work to a certain MIT lab that invented the techni--- oh wait..
149.
by kanzure 9y ago
You can label receptors with aptamers and other technology, and then sequence the aptamer labels (or whatever). Many in situ sequencing techniques can be applied here. Note, however, that this requires more steps than simply scanning with e
150.
by kanzure 9y ago
I think they probably haven't even sorted out their intentions at this point. But you know, these things just have a way of developing on their own just by tiny nudges at the beginning. For an overview of the GP-write project, see the

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