jryb

21 ms·

211.
by jryb 5y ago
True, but Covid has the additional trait of being transmissible. It's reasonably likely that anyone sick enough to need hospitalization passed the infection on to someone else at some point. And it takes just a few minutes to almost co
212.
by jryb 5y ago
I don’t see that people will follow that line of thinking. i’ve never heard these terms until recently, and my instinct was to assume that they’re new phenomena (clearly naive, but that’s just the immediate gut reaction). and given that wea
213.
by jryb 5y ago
I'm sure the readings that other people linked will be useful, but two points to give some intuition: 1. Genes don't have to be optimal, or even close to optimal to work. They just have to be good enough. 2. Nature loves to copy.
214.
by jryb 5y ago
That's true, but I don't see why the two couldn't be used in tandem, thus reducing AC power consumption substantially.
215.
by jryb 5y ago
The problem is really that there are strong incentives to produce this stuff, usually from the universities or hospitals themselves. These aren’t prestigious places, and it’s not in their interest to spotlight how many garbage papers they p
216.
by jryb 5y ago
Every ergonomic chair I've ever tried was wrong. I just don't understand it. I decided to just learn every skill required to make my own.
217.
by jryb 5y ago
Not mentioned in this article is that they’re still working on the Y chromosome, so there’s more work to be done, but it’s still a monumental achievement.
218.
by jryb 5y ago
I had mostly stopped reading books for about ten years, but then discovered I could absolutely devour audiobooks. I “read” more books in 2019 than I had in the previous decade. I think it’s a combination of being able to listen while doing
219.
by jryb 5y ago
we can’t simulate a single protein long enough to determine how it folds, even with a supercomputer. we’re so many orders of magnitude away from such a thing it’s basically unthinkable.
220.
by jryb 6y ago
First, ochem is good and there are aspects of cas proteins that you need ochem to understand, but you'll probably want to take biochemistry as well since it deals directly with proteins and nucleic acids (though I assume ochem is a pre
221.
by jryb 6y ago
I think that says more about the domain you own than anything else. My last name is fortunately rare enough that my email is firstname@lastname.com, and the only comments i’ve gotten are from nontechnical people who didn’t know that was pos
222.
by jryb 6y ago
To be clear, I think the comments should be readable by anyone. Maybe there could be some way for laypeople to submit questions that were subject to more strict moderation. Maybe there's too much overlap with /r/askscience -
223.
by jryb 6y ago
I've been mulling writing a general "Common misunderstandings HN has about CRISPR" blog post. I'd like to see if confronting everything head-on can change the general nature of conversations here. Maybe you could try som
224.
by jryb 6y ago
Sure, but only if you require commenters to provably have some kind of background in biology. I know that’s problematic for a number of reasons, but it’s just too much work to “fight the good fight” and explain why everyone is wrong on ever
225.
by jryb 6y ago
> If the argument is sound and based on correct premises Therein lies the rub. The problem with a layperson doing this kind of analysis is that they might not even realize that certain beliefs are unfounded assumptions. Obviously experts
226.
by jryb 6y ago
The rationale that they gave at the time was that they feared people would buy up all the masks leaving hospitals undersupplied, and that people would think that wearing a mask meant that you wouldn't also need to distance yourself fro
227.
by jryb 6y ago
With xubuntu 18.04 and 20.04 I’ve always had sound right away in zoom. So there’s definitely some way to avoid that bug on linux.
228.
by jryb 6y ago
It does feel weird to be much older than everyone else, but no one really cares. Post-docs are typically in their early 30s so you won't stand out like you would for an undergrad degree. Someone in my own cohort once asked me what year
229.
by jryb 6y ago
This sounds like a recipe for only being able to talk to Spanish teachers.
230.
by jryb 6y ago
i started paying for the new york times and wall street journal a few years ago, no regrets. the online-only options are quite cheap
231.
by jryb 6y ago
FWIW I'm a biologist, though I've only done a little bit of work on aging. > For example, if there was a human or animal genetic pattern that made the organism not age, wouldn't that organism have created many offspring (i
232.
by jryb 6y ago
My gripe with this is that the author assumes everyone has the same workload and prefers the same set of tradeoffs. I use raidz1 on my home desktop precisely because I would absolutely prefer to have to wait for a resilver than lose data. “
233.
by jryb 6y ago
FWIW, I used to process contracts for such leases in 2010 and that’s a pretty low payment. Typically these things paid $2-4k/month (not inflation adjusted). That said, these were all in suburban or urban areas, and if it’s easy enough
234.
by jryb 6y ago
I would actually turn this question around: why would you want to implement your own aggregation functionality? It's super convenient to be able to just make a histogram. And I'm sure my hexbin aggregation function would have erro
235.
by jryb 6y ago
It's worth noting that some academics cite that paper as a joke, I'm not sure how many genuine citations there are.
236.
The Next Paradigm Shift in Programming [video](youtube.com)
4 points by jryb 6y ago|0 comments
237.
by jryb 6y ago
> That is so ridiculous. Temperatures within 40 years aren't going to change by much more than they've already changed over the past 100 years. What does the absolute change matter? Things have limits. If we observe that the te
238.
by jryb 6y ago
That's unfortunately not even remotely feasible for a number of reasons. There's no effective delivery mechanism for large-scale changes, efficacy is low even when a CRISPR system does get delivered to a cell, and there can be ser
239.
by jryb 6y ago
Not really. There is biobricks ( https://parts.igem.org/Help:An_Introduction_to_BioBricks ), but you would need to have some background in biology and lab techniques to know how to use them. I'm skeptical this would ever
240.
by jryb 6y ago
Well, there certainly may be other motivations at play, but it's also easier to keep foreign grants secret. The NIH, NSF, and American Cancer Society all make their awards public and searchable (I assume it's true for any organiza

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