janeway

26 ms·

31.
by janeway 3y ago
It is highly likely that very old men like the one the article discusses, are likely to have accumulated potentially damaging somatic variants in DNA that will be passed onto their child.
32.
by janeway 3y ago
I am sure I miss the context but I guess the point is that authors were sick of hearing about the promise of statistical analysis and epidemiology which will outperform classical medical approach - slandering the BMJ several times for some
33.
by janeway 3y ago
If I have a choice of two pieces of software I am definitely using the one with the most stars first. I never considered that authors might have paid for stars. I wonder, when you go to StackOverflow, if you would start by checking answers
34.
by janeway 3y ago
Agreed, however a massive fallacy in science is that the more people keep repeating “hypotheses”, the more likely you are to be persuaded by spurious results / false positives. With enough attention large scale statistical analysis sho
35.
by janeway 3y ago
I have to argue against this - humbly as an expert with several degrees in microbiology, immunology, genetics, host-pathogen interaction, university lecturing, etc. The genetic basis of immunology is amazingly complex. To assign 90% autoinf
36.
by janeway 3y ago
I find it so disappointing when giants of science/tech declare the results of their experiment with GPT, after asking a few single-line questions. I remember my first time using a computer; not really knowing what else to do with it af
37.
by janeway 3y ago
The second counter adds and subtracts values other than 1 and therefore seems broken.
38.
by janeway 3y ago
A genuine Q: if the LLM was from a purely non-profit company that gave out their AI for free, would you mind your code being used? Would you in fact be proud that it has made a useful contribution? Assuming that the outcome does not affect
39.
by janeway 3y ago
It sucks that people will be out of commission once AI can do the same work basically for free. For years I have always felt that with more tax and a sort of “freedom fund” more people will be able to make “free” stuff in public for the glo
40.
by janeway 3y ago
Seems like if it can eventually test that the output meets the criteria then it will excel.
41.
by janeway 3y ago
I prefer this but if you ever have some post that triggers keywords then your whole domain may be shadow banned and you will never know.
42.
by janeway 3y ago
10% of remaining skills are worth 1000x ? Yeah, the reminds me of the AT&T switchboard operators who agree that the new automated systems work but they will never fully replace humans because the customer wants to talk to a human operat
43.
by janeway 3y ago
A blurb with no content to that is actually just a reference to their podcast episode. I didn’t see a link to the podcast show so I check my podcast app. No result matching the name. Return to the article - blocked by view limit without acc
44.
by janeway 3y ago
According to wikipedia it had 14 employees, and in 2007 had 7 million viewers per month. I wonder if Amazon wants to repurpose somehow or just jettison its less profitable arms?
45.
by janeway 4y ago
Then don’t review it. I spend months or years writing papers. A voluntary reviewer who won’t bother reading is not helpful.
46.
by janeway 4y ago
Didn’t they spend hundreds of millions running the training data or something? How are some open-source hackers going to do it?
47.
by janeway 4y ago
I think this clip section says a lot - if videos are permitted as replies. https://youtube.com/watch?v=MNtjSMvcjzs&t=211s
48.
by janeway 4y ago
I am going to ask my accountant why she dose not have a “automatic calculator not used” badge.
49.
by janeway 4y ago
There will probably be no “real texts”, just key facts. Your personal AI can phrase the content to your taste based on the context.
50.
by janeway 4y ago
Credit Suisse is a investment bank. UBS is a typical personal bank for majority of Suisse people and they also offer a few personal investment options. They have a separate investment side.
51.
by janeway 4y ago
I am delighted to hear that children are already adopting the new tech. Sure there will be kinks for a while where no one bothers with the reading or writing assignments. But shortly that will smooth out as everyone gets on even ground. Wri
52.
by janeway 4y ago
Only ChatGPT. I usually state bullet points and pseudocode and ask for answer, or current code with request to fix the error. With good requests I usually get a working answer but sometimes need careful checking.
53.
by janeway 4y ago
Here is my example. In the last two weeks I have rewritten, from scratch, one of my genomics pipelines which can analyse 1000 clinical exomes in a few hours to return candidate genetic causes of rare disease. * 42 scripts/programs. * 3
54.
by janeway 4y ago
I modelled my whole house including very piece of furniture. It is very “finicky” as you describe. It’s good enough for my amateur use with manual clicking. (There’s probably a programmatic option that I don’t know). However if I was a pro
55.
by janeway 4y ago
That is the goal but not that simple. In most cases, the original disease-causing stem cells are effectively eliminated by the conditioning regimen (high-dose chemotherapy and/or radiation) used before the (autologous) transplantation,
56.
by janeway 4y ago
:D An episode of X-Files also. But it is mind blowing having the “conversation” with a real chat AI. Malevolent or not.
57.
by janeway 4y ago
I spent a night asking chatgpt to write my story basically the same as “Ex Machina” the movie (which we also “discussed”). In summary, it wrote convincingly from the perspective of an AI character, first detailing point-by-point why it is p
58.
by janeway 4y ago
Approximately 20% of rare diseases get diagnosis in my lab. Note these are usually very extreme cases where the people are quite sick. More common genetic diseases are picked up by routine clinical genetics which don’t reach me. Interesting
59.
by janeway 4y ago
Well I spend my life dedicated to “freaks like us”. For every one person who takes years to diagnose, there will be 100 in future that we can instantly treat. (1) it helps people who need it, and (2) it can unlock new mysteries of biology t
60.
by janeway 4y ago
Good call IMO. If they still offer the download options, take all files: fastq, bam, vcf. Fastq is the raw data and can be used again as methods improve. Download it twice and check the files are the same. The problem with fastq is that it

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