iso1337

12 ms·

61.
by iso1337 8y ago
Many of the article titles on Bloomberg etc seem to have turned into clickbait in the last few years. I suppose that’s what works for driving clicks or maybe I have just wised up to it as I grew older. I remember a 10th or 11th grade Engli
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by iso1337 8y ago
There are no publications, why would anyone trust (eg waste months and months of followup experiments) on your predictions? Anyone can spit out a DNA sequence, almost no one can guarantee you that it will work (express in your host, perform
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by iso1337 8y ago
Thanks! Super interesting. I don’t live in the EU, but how does public infrastructure funding work? Are there no funds to invest in infrastructure? It seems like trading partners would benefit a lot from a more connected Romania.
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by iso1337 8y ago
kleppmann’s book: designing data-intensive applications. It’s very well written, but maybe doesn’t have as much in the way of exercises.
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by iso1337 8y ago
According to Wikipedia Romania has: 22,247 km (13,824 mi) of railroad tracks And 807 km of motorways In contrast the UK (similarly sized, within 2% of area) has 16000 km of railway and 3688 km of highway https://en.m.wikipedia.or
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by iso1337 8y ago
I try to not read that much news and instead try to read books. The quality of the news is decreasing to Facebook/reddit levels and designed to increase engagement by preying on your emotions. It’s much like marketing. The book Factfu
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by iso1337 8y ago
Lots of photos. It’s so easy to take photos, and with Live Photo’s (or whatever the mini video clips are called), that storage fills up even faster.
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by iso1337 8y ago
Yeah, re-use is always preferable. It often goes against ever-increasing standard of hygiene. It used to be common to collect used glass bottles and re-use them. That practice still happens in countries like Thailand and Vietnam.
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by iso1337 8y ago
It now costs ~427k/apt to build in SF. https://www.spur.org/news/2018-05-09/it-all-adds-growing-cos... I'm not sure what the rule of thumb is for commercial builders, but for real estate investors, a goo
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by iso1337 8y ago
PFOA/PFAs are also widely used as DWR (Durable Water Repellant) for clothing. Even Patagonia still uses chemicals in this class (or did as of 2015): https://www.patagonia.com/blog/2015/03/our-dwr-problem&
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by iso1337 8y ago
Most compostable bio plastics are made of Poly-lactic acid (lactic acid is the stuff that gives that burning feeling in your muscles after a workout) from corn. PLA can compost in industrial sites, but (edit: add a not here) in normal envir
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by iso1337 8y ago
Harris ranch (or whatever big cow op is on I-5). (36.3057129, -120.2729291) The solar project is Panoche Valley, I don’t think any satellite pics are new enough to show progress There’s a map here: https://www.panochevalleysolar.
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by iso1337 8y ago
I agree that environmental costs of beef production are quite high. For me, personally, what also matters is the relative ranking of impacts. I did some research into this and here are the top personal contributors to GHG emissions (presum
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by iso1337 8y ago
1) taxing vacant properties: Vancouver started this, although with the intent of keeping out foreign riff raff. Eg, there may be loopholes for the longtime BC residents who just happen to own a second condo. It will be interesting to see h
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by iso1337 8y ago
I’m skeptical about the conspiracy claims about how livestock were THE leading cause of GHG and looked up my own sources. The EPA doesn’t place livestock as the leading cause of GHG. https://www.epa.gov/ghgemissions/sou
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by iso1337 8y ago
In California, Sierra Club has apparently been co-opted by NIMBYs who basically use environmentalism as a cover to stop any new development against entrenched interests. The good thing (at least wrt to the posted s article) is that the majo
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by iso1337 8y ago
Ironically, environmental groups sued the project and forced it to be 1/3 the original size. https://www.mercurynews.com/2017/07/21/giant-solar-project-r... Driving down I-5, the smells and sights from s
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by iso1337 8y ago
TurboTax
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by iso1337 8y ago
Indeed, you can look at this sirtuin boondoggle https://blogs.sciencemag.org/pipeline/archives/2011/09/22/th... https://blogs.sciencemag.org/pipeline/archives/2011/12&
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by iso1337 8y ago
Usually the cost of doing the experiments precludes large sample sizes. And you would be shocked at the lack of statistical education amongst biologists. Often many them freely admit that they chose biology because they like science but ar
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by iso1337 8y ago
Part of the answer here comes down to the size of the effect. If the effect size is large, then you can be pretty sloppy with your statistics - in some ways it doesn’t matter because it’s almost a qualitative/binary difference. Obvious
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by iso1337 8y ago
I don’t think the author has the causality correct here, at least for biosciences. The statistical problems existed long before omics, big data, etc. Most of the graduate programs don’t require students to take statistics, or if they do, i
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by iso1337 8y ago
Sounds interesting. You should also post to bogleheads if you haven’t already.
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by iso1337 8y ago
Seems like those professors should be recorded and then put on YouTube. They could inspire and reach many more people that way! It’s funny because the marketing from Universities often highlight the professional value of a degree, essentia
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by iso1337 8y ago
Great details! Makes you think that we should really be getting rid of gas pipelines and making electric-only houses. Maybe you wouldn’t even need to get rid of the pipeline during decommissioning? Just turn off the source and drain the n
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by iso1337 8y ago
Okay by me as long as you’re willing to pay more.
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by iso1337 8y ago
One could argue that the state of the art is now benchling. But I have similar thoughts on the economics of building software to researchers. The domain is complex, the customers require a high level of correctness, and features are often
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by iso1337 8y ago
eh, it still took ~56 real-world attempts to get two functional designs. That's not even quantifying how strongly they fluoresce, and other qualitative/quantitative aspects (eg, how good of a GFP were these proteins). It's
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by iso1337 8y ago
What I remember from Japan are ramen restaurants where you buy tokens from a vending machine before you go into the restaurant. Seemed pretty efficient and those places kept simple ramen at around $6-$8 per bowl in Osaka. You would then g
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by iso1337 8y ago
Some ideas: European style: Higher prices, shorter hours. Japanese style: more automation, vending machines for everything. Anecdotally, I haven’t seen those issues you mention with retail. Fundamentally the problem is that the price people

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