gilleain

39 ms·

631.
by gilleain 5y ago
I have seen a distinction made between "bioinformatics" - analysing biological data with software - and "computational biology" - using biological systems to do computing. What OP seems to be talking about is systems mod
632.
by gilleain 5y ago
That's category2 - personal favorite. So long as he is wearing a giant leather trenchcoat, shooting people while sitting in a chair, saying "this is a little mutherfucking thing called justice", and letting someone younger fi
633.
by gilleain 5y ago
This makes sense if you consider 'quality' and 'enjoyability' on two separate axes: - High quality and enjoyable? A classic. - Low quality but enjoyable? A personal favourite. - High quality but boring? Critics choice th
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by gilleain 5y ago
I agree with your general point, but Kings and Queens absolutely had to consider other people. Specifically, most rulers had some kind of patronage network where they gave out 'gifts' like land, or the right to collect taxes, in r
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by gilleain 5y ago
notepad++ is a far superior product imo. so many useful features out of the box, and has plugins also. * search in all opened docs * find/replace with regex * tabs to space * line operations etc Very useful, and for my workflows on Win
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by gilleain 5y ago
I dont know why, but this made me laugh. I mean its horrible, the idea of restricting reading in prison based on such an obvious lie. The elaborate scenario that you would have to construct such that a message encoded into a book was the on
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by gilleain 5y ago
I have been watching a youtube series on the collapse of civilisations : https://m.youtube.com/channel/UCT6Y5JJPKe_JDMivpKgVXew episode 2 is about the Bronze Age Collapse and the interesting thing for me is how little
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by gilleain 5y ago
I think I understand something of your point of view. It is a little hard to be sympathetic for someone who had many resources to sort out what was a relatively minor problem. As others have pointed out, she does acknowledge this privilege
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by gilleain 5y ago
Yes it seems like a combination of magnifying and muddling information. Say, for example, a cancer researcher makes a statement like "Red wine contains compounds that might protect from some cancers" - not very interesting as news
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by gilleain 5y ago
>Everyone should learn how to extinguish a fore for each class (A, B, C, D) I did not even understand this one! :)
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by gilleain 5y ago
Did North Vietnam lose the war?
642.
by gilleain 5y ago
I think of the problems that the homeless face as being like an evil roundabout. Although you enter with one of mental illness, addiction, or despair (or several, the analogy is imperfect) the roundabout mixes these up until you have them a
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by gilleain 5y ago
Is that a regular faced polyhedra? From a google search it seems like this is a class of shape that combines flat faces and curved ones.
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by gilleain 5y ago
Well I would consider Adam and Noah to be mythologial rather than ancient. Even Moses, who might have lived around the 13th century bc would have been 1000 years after Sargon of Akkad. There is a lot of history to go around, so many peoples
645.
by gilleain 5y ago
So 'superstition' is defined as non-doctrinal belief. That would make it impossible for Catholicism to be superstitious by definition. I guess I see what you mean by a religion of Roman lawyers... To the Aztecs, presumably, there
646.
by gilleain 5y ago
So the simple possibility is rigid docking to get a surface between proteins. As with everything in biology, things can be more complicated. For example, from here : https://elifesciences.org/articles/22889 it starts w
647.
by gilleain 5y ago
That makes sense, thanks. With regards to abiogenesis, that is a wonderful area for wild speculation. I say that having done a tiny bit of that myself :) Certainly it would be helpful to have small-molecule catalysts to bootstrap life into
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by gilleain 5y ago
Well at least they've moved on from the days of alchemy where the tendency was to make up your own notation and jargon to obscure what you actually did :)
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by gilleain 5y ago
I think its the nature of the thing. Some fields are easy to 'big picture' - like physics (apart from quantum-level?) or biology. If they relate to everyday experience then that is surely easier. Chemistry often deals with the eve
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by gilleain 5y ago
> So now there's a link between biological catalysis and artificial catalysis that didn't exist before. Not sure I understand that point. There are plenty of enzymatic reactions that rely on metals. Presumably the point is that
651.
by gilleain 5y ago
> whether this really all makes perfect sense to chemists themselves? Yes. Obviously! Someone working in a technical field will understand the jargon and notation of that field. Certainly if you are working in (say) physical chemistry, y
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by gilleain 5y ago
"Political reasons" being that one imprisoned the other! :) Or, more exactly - Mary was deposed and replaced with her one year old son (later James VI/James I) and imprisoned in Scotland. She then escaped, raised an army, los
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by gilleain 5y ago
Generation with constraints is a fairly common algorithm in combinatorics. When you need a set of objects with a particular structure, you could just make all possible examples and then filter out the unsuitable ones. However if there are t
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by gilleain 5y ago
It might be easier to think about these numbers if you know that the average mass of an amino acid is 110 daltons. So 180 kda is around 1,600 residues. From this paper https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3
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by gilleain 6y ago
Good spot, I should really have noticed that - seems that was not the greatest source! Yeah, they probably did get Weil mixed up with Wiles. Another good example of the difficulty of trying to analyse a polymath's work.
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by gilleain 6y ago
Presumably (am not an expert in this!) because the barrier to entry in a field of knowledge was lower in the past. As in, at one point you could read all there was to know about a subject. Also, there was more 'low hanging fruit'
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by gilleain 6y ago
The point about Leonardo da Vinci makes sense, but is definitely unfair. Of course, an art historian might assume Leonardo's mathematics was as great as his artistic ability. In practice, no one has the time or the ability to be equall
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by gilleain 6y ago
Yeah, I started to try and skim that, then realised I was not going to do it justice to summarise it! For example, discussion of 'spiritual income streams' and advowsons, and other obscure topics. I wonder how many people have kno
659.
by gilleain 6y ago
His break with The Church is usually considered frivolous because the focus is often put on his desire to divorce. The real goal was to have _legitimate_ male heirs. It was never much of a problem for kings to have affairs, even out of wedl
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by gilleain 6y ago
Ha nice visualisation. Would be amazing if this was available for more chat systems where conversations branch like this. Also, as a side note its funny that there is a lot of discussion (including Baez!) about theoretical maths, and one lo

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