gilleain

41 ms·

541.
by gilleain 4y ago
Hmm wonder how Craig Venter is getting along with his project. He was making a lot of noise about it a few years ago. Seems like he sold a company in April of this year to the University of California.
542.
by gilleain 4y ago
It's now a _solved_ problem - both theoretically (with Babai et al's paper a few years ago) and practically (with nAUTy/Bliss, and similar software). Not sure what the key paper is, but "Graph isomorphism in quasipolynom
543.
by gilleain 4y ago
Difficult question, but there's an analogous question for 'carbon-based' life - are there non-carbon based life? The answer is likely "no", simply because the number of molecules based on carbon is many orders of ma
544.
by gilleain 4y ago
Hopefully they got to see the swans. Like a fairytale, really. More seriously, what appeals to me about films like that is how 'real life' crime (as far as I can know) is not like a glamourised action movie. It is more haphazard,
545.
by gilleain 4y ago
Hah. That's so much better than the opposite - 'who wrote this terrible, buggy, badly formatted code??!' then finding it was you several years ago.
546.
by gilleain 4y ago
As with the other question, above - I think this paper proposes a database of known (experimentally verified?) reactions, rather than predicted ones. Guess they should have been clearer. RMG predicts likely reactions based on chemical kinet
547.
by gilleain 4y ago
Ah, I do not think they are proposing a database of _predicted_ chemical reactions but of _known_ reactions. I absolutely agree that enumerating reactions would suffer from combinatorial explosion (as opposed to chemical explosions, hoho).
548.
by gilleain 4y ago
Nice paper. An interesting paragraph: > This conservative state of affairs in the chemistry community is unlikely to result from some intrinsic properties of chemistry as a science. Rather, it is likely to be the product of complex hist
549.
by gilleain 4y ago
As the article describes, the enzyme in the title is a "uridine diphosphate–dependent glucosyltransferase" which "catalyzes the addition of branched glucosides to compounds in stevia". So the sweet compound is not the en
550.
by gilleain 4y ago
Do different sutures require different knots?
551.
by gilleain 4y ago
Perhaps because it relates (vaguely) to - Topology - Combinatorics? - Practical stuff like tying up boats? I like knots because of the relationship to protein folds, but hey ymmv.
552.
by gilleain 4y ago
I think I understand what you mean, but what would that 'extra context' look like? For example, could 'practical' knot tying be modelled as a sequence of states? So one state would be 'untied' and then the next
553.
by gilleain 4y ago
Reminds me of when I started gaming there was a cRPG series called the 'gold box' - pools of radiance, curse of the azure bonds, secret of the silver swords, etc. The first of these was in CGA (I guess corresponding to CMYK?) whic
554.
by gilleain 4y ago
Ithink the term 'grand correspondence' is perhaps less clear than saying an underground map is usually topological not geometric. If you look for 'geometric map tube' (or similar) you can see how the actual positions of
555.
by gilleain 4y ago
I've more than skimmed 'Visual Group Theory', it's very good. I found it extremely clear and well illustrated. There's also some companion software.
556.
by gilleain 4y ago
Yeah, I see how some of us over here could make that mistake - but still, it's pretty annoying. Perhaps you could use 'Southern Albion' instead? Or 'the south part of the Eastern Island', maybe.
557.
by gilleain 4y ago
Indeed, anyone who has two hands should be awate of chirality.
558.
by gilleain 4y ago
The use of the word 'Topology' is especially ... odd. To me, at least. I understand that it is possible to use technical terms like this in a more casual sense. Somehow it makes me think it is an attempt to use adopt 'serious
559.
by gilleain 4y ago
True, but following the ORCID link from the main author brings me to: https://www.science.org/doi/10.1126/sciadv.abm5091 which has the glorious title of 'Synthetic biology and bioelectrochemical tools for ele
560.
by gilleain 4y ago
Funny to think Blake should have chosen Newton as a symbol of excessive rationalism, given Newton's interest in alchemy. He was also religious, although an antitrinitarian - possibly not relevant to Blake's ideas of the divine. An
561.
by gilleain 4y ago
I know this is not reddit, and I know HN discourages posts that don't contribute to the discussion, but ... Man did footnote [1] make me laugh. I feel like I have not invested enough in that asset class. It's a bittersweet laughte
562.
by gilleain 4y ago
Yes, I find command line tools that have a "--dry-run" flag to be very helpful. If the tool (or script or whatever) is performing some destructive or expensive change, then having the ability to ask "what do you think I want
563.
by gilleain 4y ago
His artwork is also amazing. Somehow only a topologist could make works like it (i feel). I do wonder if his strange history is influenced by his mathematics. The idea of 'copies' of the same event but with different names seems q
564.
by gilleain 4y ago
Following one of these languages (that I had not heard of) back to its wikipedia page, I see: > In JavaOne 2003, in June, JavaSoft announced its intention to create a wholly-owned scripting language for the Java platform. This monopolous
565.
by gilleain 5y ago
Hah fair enough. I wondered if it was a non-English spelling that was all :)
566.
by gilleain 5y ago
Out of curiosity, why do you write 'Thritium' for 'Tritium'?
567.
by gilleain 5y ago
Good point, although it makes me wonder what a 'mechanical metabolism' might be. I've heard of the worm with a fool's gold shoe before (or iron sulfide of some kind). There are also Antarctic fish that make antifreeze pr
568.
by gilleain 5y ago
Sigh, yes I was thinking something similar. Not sure how we got from suspect sweet stores to illegal immigrants ... Thanks, your comment made me smile.
569.
by gilleain 5y ago
Only one point is 'off' though: 1) "cheap signage" - so they are minimising costs? 2) "expensive stock" - maximising profits 3) "low footfall" - this does seem odd I still think that they get some dea
570.
by gilleain 5y ago
A beautiful analogy ... unfortunately just an analogy. One book I liked in theoretical biology was "Cats Paws and Catapults" by Steve Vogel (978-0393319903) about how biology and technology adopt different designs due to use of di

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