flobosg

16 ms·

241.
by flobosg 2y ago
(1998) or (2014) > This page was originally maintained by Stephen Worth. Thanks to John K. for funding its production. Preserved by Kip Williams and restored in 2014 by Harry McCracken. > The Warner Brothers Cartoon Companion is Copyr
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Zerowriter Ink – Your open-source e-paper typewriter(crowdsupply.com)
3 points by flobosg 2y ago|0 comments
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by flobosg 2y ago
Even though I’m not working in structural biology anymore, this is a topic that lies close to my heart. * Check out Jane Richardson’s The Anatomy and Taxonomy of Protein Structures ( http://kinemage.biochem.duke.edu/teachin
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by flobosg 2y ago
From a few months ago: The Ballmer Peak: An Empirical Search – https://arxiv.org/abs/2404.10002 ( https://news.ycombinator.com/item?id=40062892 )
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by flobosg 2y ago
> Inevitably, with an audience that size, a loud minority made their negative feelings known. Instead of letting these comments deflate them, they turned the tables on them. “Primus sucks!”
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by flobosg 2y ago
Folding@home and protein structure prediction methods such as AlphaFold address related but different questions. The former intends to describe the process of a protein undergoing folding over time, while the latter tries to determine the m
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by flobosg 2y ago
Folding@home uses Rosetta only to generate initial conformations[1], but the actual simulation is based on Markov State Models. Note that there is another distributed computing project for Rosetta, Rosetta@home. [1]: https://fold
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by flobosg 2y ago
Yeah, I checked the preprint. Engineering serine hydrolases is kind of a low-hanging fruit, but a great starting point nevertheless!
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Ten simple rules for scientific code review(journals.plos.org)
3 points by flobosg 2y ago|1 comments
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by flobosg 2y ago
> it's also unclear how many of these sequences folded into the predicted 3d structure The whitepaper depicts some successful cases, determined by X-ray crystallography or cryo-EM.
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by flobosg 2y ago
In my humble opinion, this work is not that innovative: de novo protein binders have been done to death, either by AI approaches or otherwise. Check out the work by David Baker’s group, for instance. They have a myriad of examples already
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by flobosg 2y ago
The Hershey fonts come to mind: https://en.wikipedia.org/wiki/Hershey_fonts
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by flobosg 2y ago
Here’s a live demo: https://youtu.be/pdmODVYPDLA
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by flobosg 2y ago
The original press release: https://www.cam.ac.uk/research/news/mothers-gut-microbiome-d...
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by flobosg 2y ago
Unedited title: ‘They’re about two years behind’: fears for children born during lockdown as they start at school
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by flobosg 2y ago
(2014)
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by flobosg 2y ago
For more pieces in just intonation, check out https://en.wikipedia.org/wiki/List_of_compositions_in_just_i...
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by flobosg 2y ago
I was expecting novel modes of action but unfortunately it is not the case here: > Our findings indicate that the tested AMPs from AMPSphere primarily exert their effects by permeabilizing the outer membrane rather than depolarizing the
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by flobosg 2y ago
> Television? The word is half Greek and half Latin. No good will come of this device. ―C. P. Scott
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by flobosg 2y ago
“Beautiful Racket” comes to mind: https://beautifulracket.com/
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by flobosg 2y ago
The article reminded me of Andy Baio introducing his son to video games in chronological order – https://waxy.org/2014/12/playing-with-my-son/
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by flobosg 2y ago
* Get Your Shit Together – https://getyourshittogether.org/ * What to Do Before You Die: A Tech Checklist – https://archive.is/6vjqQ * Cheat Sheet For If I’m Gone – https://archive.is/lnWX6
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by flobosg 2y ago
Related: “How to Make Fermented Hot Sauce” – https://www.seriouseats.com/fermented-hot-sauce-how-to ( https://news.ycombinator.com/item?id=32486504 )
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by flobosg 2y ago
> But minerals are different from molecules in some important ways. Instead of free-floating clusters of atoms, they are lattices that include some disorder in their structures. Not sure if I am following this. Is the author implying tha
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by flobosg 2y ago
Not entirely what you asked, but check out regulons: https://en.wikipedia.org/wiki/Regulon
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by flobosg 2y ago
https://archive.is/dLFxv
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by flobosg 2y ago
To be fair, everything is poison at the right dose.
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by flobosg 2y ago
There’s a Zero variant (which I haven’t tried but plan to): https://www.club-mate-shop.de/getraenke/46/club-mate-zero
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by flobosg 2y ago
Sioyek uses the MuPDF engine, which supports EPUB: https://mupdf.com/
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by flobosg 2y ago
Fun fact: LEaP’s original author, Christian Schafmeister, went on to create a Common Lisp implementation that uses C++ and LLVM for applications in molecular nanotechnology: https://www.youtube.com/watch?v=8X69_42Mj-g

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