flobosg

71 ms·

931.
by flobosg 6y ago
My thoughts exactly! Somewhere, Margaret O. Dayhoff is weeping.
932.
by flobosg 6y ago
Sequencing technologies have improved immensely over the last decade and a half. And, in this particular case, getting the sample RNA is incredibly easy, since its purity and integrity in the vial is quite high.
933.
by flobosg 6y ago
The authors reverse engineered the sequences of the vaccines, obtaining them from the remaining mRNA present in the vials. “Assembly” in this case means that they merged several short sequences they obtained, each representing a fragment of
934.
by flobosg 6y ago
In the BioNTech/Pfizer mRNA, the 3' (or the latter) half of the 3'-UTR comes from human mitochondrial 12S rRNA. The Moderna one has the 3'-UTR of the alpha subunit of human hemoglobin.
935.
by flobosg 6y ago
I’m not a linguist, but here’s how I see it: They are analogous expressions, but as I mentioned, «estar» is not considered an auxiliary verb in Spanish conjugation. You only have «haber», while English has “to be”, “to have” and “to do”. So
936.
by flobosg 6y ago
It depends on how you define a tense. Strictly speaking, English has no morphological future tense, but some tense-aspect combinations are commonly referred to as a “future tense”. In Spanish, unlike «haber», «estar» is not considered an
937.
by flobosg 6y ago
> I was puzzled by the one about the present continuous tense, which does exist in Spanish According to Spanish grammar, what would be considered the Spanish analog of the English present continuous is formally classified not as a tense,
938.
by flobosg 6y ago
The structural mutation described in the study likely happened as “circumstances of their birth”: a gene insertion in the germline genome. > This study suggests that's not the only way these genetic changes happen The study says not
939.
by flobosg 6y ago
Not sure what you meant with that. This gene transfer event is a mutation and as such is also being subject to natural selection.
940.
by flobosg 6y ago
They assumed HGT because they couldn’t find any ortholog phenolic glucoside malonyltransferase genes in related whitefly species, eliminating convergent evolution as a possible explanation. In addition, the phylogenetic analysis showed that
941.
by flobosg 6y ago
Takahashi Meijin, a former Hudson Soft executive, was famous in the 80s for being able to mash a button 16 times per second: https://www.youtube.com/watch?v=oJ4lmAFB7d4
942.
by flobosg 6y ago
Not Classic Tetris, but Tetris 99[1] and the Tetris: The Grand Master series[2] are also worth checking out if you are into competitive Tetris. [1]: https://www.youtube.com/watch?v=Mm6t5IKVGsM [2]: https://www.yo
943.
by flobosg 6y ago
By the way, the Bad Apple!! video has been ported to several retro platforms: https://en.wikipedia.org/wiki/Bad_Apple!!#Demoscene
944.
by flobosg 6y ago
There’s an open letter in support of RMS as well: https://rms-support-letter.github.io/
945.
by flobosg 6y ago
The syncing of the visuals to the music brings to mind the video for The Chemical Brothers’ Star Guitar: https://www.youtube.com/watch?v=0S43IwBF0uM
946.
by flobosg 6y ago
> Are they? Do you have a link? I saw from the New York Times tracker that China has vaccinated 74 million of their own citizens. Are you saying they've sent more vaccines to the rest of the world than the 74 million they've us
947.
by flobosg 6y ago
That engineer was Jamie Zawinski, by the way.
948.
by flobosg 6y ago
There’s a capture in the Wayback Machine: https://web.archive.org/web/20180822190926/https://www.wired...
949.
by flobosg 6y ago
There are no known cases of the 501.V2 variant in either Chile or Peru, and the US has only had 143 cases by now. Besides, the trials were probably done months ago. If I’m not wrong, the Chilean one started in December.
950.
by flobosg 6y ago
See also the ReScience journal [1,2] and its Ten Years Reproducibility Challenge [3,4] from last year that tried to run scientific code written more than a decade ago. [1]: https://rescience.github.io/ [2]: https:/&#x
951.
by flobosg 6y ago
I would add Carl Zimmer’s “A Planet of Viruses” as well.
952.
by flobosg 6y ago
> viruses are made of RNA Depending on the species, a virus can contain either DNA or RNA as its genetic material. Check out the Baltimore classification ( https://en.wikipedia.org/wiki/Baltimore_classification ) for
953.
by flobosg 6y ago
Joey Hess, a former Debian developer, has been doing it for a while: https://joeyh.name/blog/
954.
by flobosg 6y ago
It’s very real and even expanded to other countries over the last decade.
955.
by flobosg 6y ago
Related: The Centre for Applied Eschatology - https://www.appliedeschatology.com/ We’re working for no tomorrow, today.
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How Chile became an unlikely winner in the Covid-19 vaccine race(theconversation.com)
1 points by flobosg 6y ago|0 comments
957.
by flobosg 6y ago
That’s a good point. In this case the spike-derived peptides have no known N-linked glycosylation sites[1] and the paper you mentioned showed that at least some of those epitopes are accessible even when taking glycans into consideration. [
958.
by flobosg 6y ago
I agree on those points. That’s why I only focused on the cross-reactivity part of your post. Call it a nitpick, if you want.
959.
by flobosg 6y ago
> What happens if a sub-sequence of peptide matches with one of our own's body proteins and our immune system starts building antibody against it? The peptide sequences are listed on the whitepaper, so it’s a matter of BLASTing[1] t
960.
by flobosg 6y ago
It seems that words for tea that derived from "cha" spread across land, while the ones originating from "tea" developed over sea routes. https://qz.com/1176962/map-how-the-word-tea-spread-over-land..

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