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flobosg
searching PlanetScale…
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27 ms
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301.
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flobosg
2y ago
> people are looser in the south What does “loose” mean in this context? My first impression would be that the accent in northern Chile is “looser” than the south.
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flobosg
2y ago
> It is also mind boggling that rail is not more popular there. A long, slim country is ideal for high speed rail. See one of my other comments in this post regarding the rail in Chile.
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flobosg
2y ago
Trivia question: how many time zones does Chile have?
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flobosg
2y ago
Enter the Mapuche ( https://en.wikipedia.org/wiki/Mapuche ), whom the Inca tried (and failed) to conquer.
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flobosg
2y ago
In the 2000s the Chilean state railway company was involved in a huge corruption scandal as well as bad administrative practices. It’s been slowly recovering, but rail services in Chile still leave a lot to be desired.
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flobosg
2y ago
There are regional variations, but the difference is less than what you would probably expect, applying mostly to intonation/cadence (more marked and melodic in the south, less so in the north) and some vocabulary. Most of the variatio
307.
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flobosg
2y ago
I like how the author used Kinopio for his “Uses This” interview: https://usesthis.com/interviews/pirijan/ And I instantly recognized that artwork from Hirō Isono: Seiken Densetsu 3 ! https://archive.o
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flobosg
2y ago
> because ab-initio means something entirely different I agree, and that’s probably why they switched to de novo prediction/design at some point.
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flobosg
2y ago
> Different proteins can also be related to each other. Even when the sequence similarity between two proteins is low, because of evolutionary pressures, this similarity tends to be concentrated where it matters, which is the binding sit
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flobosg
2y ago
> To me the only part that seems miraculous is that it seems like we can predict novel structures (previously unknown conformations) using small fragments of templates rather than entire protein domains. Just to add a bit of context: Ros
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flobosg
2y ago
See also the video game Return of the Obra Dinn ( https://en.wikipedia.org/wiki/Return_of_the_Obra_Dinn ) as well as the developer log entry about dithering ( https://forums.tigsource.com/index.php?topic
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flobosg
2y ago
(2022)
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flobosg
2y ago
David Goodsell’s Molecular Landscapes (see https://pdb101.rcsb.org/sci-art/goodsell-gallery/mycoplasma-... or https://pdb101.rcsb.org/sci-art/goodsell-gallery/model-of-a-... ) represent
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flobosg
2y ago
Looks like hemoglobin (good ol’ 4HHB[1]) to me. [1]: https://www.rcsb.org/structure/4HHB
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flobosg
2y ago
One of my favorite class of proteins to look at. Check those neatly ordered residues at the water-binding interface!
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flobosg
2y ago
Along those lines: When a postdoc in my lab committed fraud, I had to face my own culpability – https://news.ycombinator.com/item?id=38766484
317.
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flobosg
2y ago
I’ll take the chance to recommend one of my favorite books, the Oulipo-inspired Eunoia by Christian Bök: https://en.wikipedia.org/wiki/Eunoia_(book)
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flobosg
2y ago
I am confused now. Are you arguing then that the distinction is dependent on region and not language? Because that is precisely what I said in a previous comment.
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flobosg
2y ago
> The article is written in english which is important here. From said article: > This paper is a translation of the original paper in Spanish “Computadoras Mexicanas: Una Breve Reseña Técnica e Histórica” by Daniel Ortiz Arroyo, Fran
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flobosg
2y ago
Goodhart’s law at work.
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flobosg
2y ago
> Chile (South america) is not in the same continent as Mexico (North america). The distinction is region-dependent: https://en.wikipedia.org/wiki/Americas#Spanish
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flobosg
2y ago
My thoughts exactly. More HN links here: https://news.ycombinator.com/item?id=39307700
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flobosg
2y ago
Ctrl-B PgUp/PgDown enters scroll mode.
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flobosg
2y ago
Similar use case here, but in a biotech company.
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flobosg
2y ago
> What a terrible night to have a learning model. They blew it: It’s “What a horrible night…”
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flobosg
2y ago
(2017)
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flobosg
2y ago
From personal experience, rasterizing vector art for a pixel art aesthetic usually leaves a lot to be desired, especially when you look at angled lines and curved shapes. That being said, there are rasterizing projects with a focus on pixel
328.
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flobosg
2y ago
…and also one of the ingredients for the hacker-approved Tschunk! https://en.wikipedia.org/wiki/Club-Mate#Tschunk
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flobosg
2y ago
> You drink your yerba mate, whether hot or cold, unsweetened What about adding additional herbs ( yuyos ) for flavoring? Not fully sure, but I have the impression that it is mostly a Paraguayan thing.
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flobosg
2y ago
A bit more information about the default Windows 10 wallpapers: https://www.raykovich.com/project/windows-imagery
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