flobosg

22 ms·

331.
by flobosg 2y ago
Sure but, in my opinion, you can tell all of those in both plots. The crossmarks are not even needed.
332.
by flobosg 2y ago
If a chemist wants to look at the actual point values, wouldn't a reference table be more useful and precise?
333.
by flobosg 2y ago
Some weeks ago, coincidentally, I took an old drugstore brand disposable camera I found lying around in my flat for a weekend trip. The AA battery was corroded and dead, but otherwise the camera worked just fine. The trip was actually a bac
334.
by flobosg 2y ago
Thank you for the write-up! I also caught a small typo: > You can form an opinion about the density of these websites simply by looking at an image for a franction of a second.
335.
by flobosg 2y ago
Related: Why Japanese Websites Look So Different – https://news.ycombinator.com/item?id=37722348
336.
by flobosg 2y ago
> Tufte's examples of graphics with a low data-ink ratio (left) and a high one (right). Isn't it the other way around? High on the left and low on the right? EDIT: Based on the alt text both images should be swapped.
337.
by flobosg 2y ago
> (side note: is it really a 'foot'note if it's not in the footer of the page?) These are rather sidenotes (or margin notes).
338.
by flobosg 2y ago
I built something similar using a spare ThinkPad x220 I had lying around and a minimal Debian installation. I would prefer something closer to the AlphaSmart Neo line of digital typewriters, though.
339.
by flobosg 2y ago
Parafilm? 100% agreed. I’ve thought about buying a roll, which will probably last me for a lifetime. One of these days, maybe.
340.
by flobosg 2y ago
And a nuclear membrane in eukaryotes as well.
341.
by flobosg 2y ago
And cover the flask with some shrink wrap (maybe with a tiny hole punched into it) to hinder steam release.
342.
by flobosg 2y ago
> has been dead in the water for a while now Both are under active development and are used in several transcriptomics atlas projects, as far as I can tell.
343.
by flobosg 2y ago
> intercalculation with DNA I assume you meant intercalation [1], right? [1]: https://en.wikipedia.org/wiki/Intercalation_(biochemistry)
344.
by flobosg 2y ago
I also had to prepare agarose gels with EtBr in the past, but now there are several alternatives for gel staining, such as SYBR Green.
345.
by flobosg 2y ago
Python is catching up on single-cell transcriptomics; see AnnData, Scanpy, et al.
346.
by flobosg 2y ago
I actually used a slightly modified version of his Illustrate program ( https://github.com/ccsb-scripps/Illustrate ) for rendering. The toughest part was getting the right pose; the bot tried to pick an optimal one, but
347.
by flobosg 2y ago
Another example of interventions with reversed outcomes: “baby simulator” programs increase the rate of teen pregnancy – https://www.statnews.com/2016/08/25/infant-simulators-teen-p...
348.
by flobosg 2y ago
Sure! Here it is: https://twitter.com/molecularblobs
349.
by flobosg 2y ago
I’m a huge fan of your RibbonDiagrams bot, so much so that it inspired me to write my own one (using a different protein representation, of course). Thank you!
350.
by flobosg 2y ago
He’s using the alpha carbons (CA) adjacent to the carbonyl groups as well as the carbonyl oxygens (O), approximating the peptide plane. In addition he incorporates heteroatoms, so the scoring function takes ligands into account, if present.
351.
by flobosg 2y ago
I’m not sure how is he orienting the camera in his library ( https://github.com/fogleman/ribbon ), but the usual approach is to maximize what is shown on the X and Y axes by e.g. aligning principal components (as PyMOL d
352.
by flobosg 2y ago
If you like, you can purchase plotter ribbon diagrams from him: https://www.michaelfogleman.com/plotter/
353.
by flobosg 2y ago
> The big science news on Friday was that for the first time we have done this for an insect brain. If I’m not wrong, the Drosophila connectome was released last year.
354.
by flobosg 2y ago
I haven’t watched it yet, but reading this article a while ago got me interested: 'Patlabor 2: The Movie' has stunningly realistic aerial combat – https://taskandpurpose.com/culture/realistic-aerial-combat-m
355.
by flobosg 2y ago
Most reagents and kits for molecular cloning will be fine at -20°C.
356.
by flobosg 2y ago
In a way it is already incorporated. Broadly speaking, chaperones function by restricting the available conformational sampling space for the protein to fold. Some researchers even consider the ribosome as a chaperone of sorts for the nasce
357.
by flobosg 2y ago
> but it is not going to predict novel folds https://www.nature.com/articles/s42003-022-03357-1
358.
by flobosg 2y ago
Related: Drawing better-looking Bézier curves – https://news.ycombinator.com/item?id=16364621
359.
by flobosg 3y ago
Keep in mind that Chilean building regulations account for much more seismic activity than the ones on the US East Coast.
360.
by flobosg 3y ago
As someone who lived for decades in a seismic country, I’d say that tremors can also be perceived. The difference lies mostly in the damage generated by the event.

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