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66 ms
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541.
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by
entee
11y ago
There are plenty of Biotech VCs in the bay area. The one I know best is Third Rock Ventures, but there are others. The timelines for success are extraordinarily long so it's not quite as splashy a space. It's almost impossible to
542.
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by
entee
11y ago
First of all, why not build the walls to the top of the ceiling? Seems like so much vertical space could be used! Second of all, how long can this last? People criticize the tech economy for causing displacement and surely that's happe
543.
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by
entee
11y ago
This is absolutely an underappreciated feature of SV, and prior to this article I had also heard it held up as one of the reasons SV has a relatively more active and larger startup environment than Boston. Given the nature of startups and t
544.
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by
entee
11y ago
I think the primary objective of a logo is to be a recognizable symbol for an organization or concept. It's not entirely clear to me that to achieve that objective the logo must fully describe the entity or be some identifiable represe
545.
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by
entee
11y ago
Trying to scrupulously avoid inflammatory descriptions but I personally believe the Republican Party has become a shadow of its former self by taking a totally uncompromising and childish approach to policy and governing. I think it's
546.
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by
entee
11y ago
Of course Hamilton will cut parts of history short, modify some and embellish others. It's a work of art that has to cram 30 years into around 3 hours of musical theater. Hamilton was probably an elitist, he also was probably not as st
547.
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by
entee
11y ago
Absolutely true, that's why there is a dead zone at the bottom of the mississippi. However there are literally tons of ammonia flowing out of places with high density and where that high ammonia still ends up in water ways after passi
548.
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by
entee
11y ago
The article makes a good point that ammonia is an integral part of our modern world, and it's pretty much impossible to get around it. However, there are also other places in which ammonia will cost energy. That fertilizer we use ends
549.
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by
entee
11y ago
Safeway is open near 24/7, some close at ~midnight, but that's pretty good. There are also tons of little convenience stores/bodegas that stay open relatively late. That said, nightlife closing at 2AM is a plus and a minus. I
550.
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by
entee
11y ago
The only thing I liked about Quip was the conversation about the doc alongside the doc. Otherwise it was kind of a not-great Google docs, a not-great Dropbox and a not-great Slack wrapped into one. That said, this was a year ago, maybe it&#
551.
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by
entee
11y ago
Science advances one funeral at a time. -Max Planck Academia is brutal, and grad school literally gets medieval on your __. In some fields though, (Biosciences in particular) if you want to be anywhere near R&D it's hard to be take
552.
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by
entee
11y ago
I think it has more to do with mutual fund regulations than public company regulations. I'm not sure how much Google has to disclose about its internals but I think it has a lot of discretion.
553.
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by
entee
11y ago
Winter has come. It's sad to see companies that are providing real, important products getting hammered for not meeting potentially impossible expectations. People have been talking about Dropbox struggling to meet its valuation for a
554.
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by
entee
11y ago
Good that these comparative tests are being done and publicized. Without clear, public performance metrics and regular accountability for those metrics, a medical test is worse than useless. That said, they didn't fail on every test, s
555.
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by
entee
11y ago
Presumably, once they actually get results that can be published they'll do so. If they don't, they'll have a lot of trouble gaining credibility in the biosciences. That said, in science bad management is kind of the norm. Ma
556.
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by
entee
11y ago
Precisely. I think he also ignores that as far back as Leonardo, artists intended to push limits, paint new subjects and invent new techniques. Take the methods of the old, sure, but try to take them somewhere new. Surely modern subjects an
557.
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by
entee
11y ago
True, not to mention performance art which by definition is ephemeral. I wish there was some middle ground between the avant-guarde that Collins decries and some of the more recent ideas in art. I think he's not correct in wholesale re
558.
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by
entee
11y ago
Also, it's not as easy as it looks to make "modern" art work. It may look easy to make a Jackson Pollock, but it's not so easy to not have it turn to mud as you make it. Perhaps not as technically difficult as an old mas
559.
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by
entee
11y ago
I think maps like this beautifully illustrate how complicated biology is. Now add in things like what the parent mentions such as cell state, external signalling systems and it gets worse. Much of this chart was mapped out using E. coli, S.
560.
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by
entee
11y ago
I think in some ways that's true, but then why does it seem to be so congealed and terrible? All of these idealists should make it better somehow no? Maybe some (not all) of the people in higher positions get appointed through more pol
561.
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by
entee
11y ago
Almost certainly true. Also, how accurate are these optical HR sensors? Chest strap monitors are somewhat more accurate than optical monitors: http://www.wareable.com/sport/heart-rate-monitors-chest-stra... And it'
562.
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by
entee
11y ago
This paper is awesome because it transparently folds the analytical approach into the experiment being conducted. There are two kinds of scientific study: those where you can run another (ideally orthogonally approaching to the same questio
563.
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by
entee
11y ago
One possible advantage the "harder" sciences have is that another study that builds on the previous one can in some ways act as a replication. If I publish something claiming bacteria has a gene X that produces phenotype Y, then a
564.
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by
entee
11y ago
As someone who was once a bench scientist, I'd love to think I was immune to these kinds of pitfalls. After all, we control things carefully in the lab, we can control many more of the inputs to an experiment, test a hypothesis by diff
565.
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by
entee
11y ago
Nevermind that perhaps the most prescribed class of psychiatric drugs has been called into question: http://blogs.scientificamerican.com/cross-check/are-antidepr... Psychiatry is a really, really hard field for canonic
566.
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by
entee
11y ago
This article touches on, but doesn't explore very much the main problem that there's only a limited number of companies that are actually worth the investment. It's not necessarily a given that if there is more money in VC mo
567.
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by
entee
11y ago
There's a huge amount of concern in the medical profession that lots of studies in the area are statistically compromised precisely because the authors gamed the statistics after the fact, or because improper metrics were used in the f
568.
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by
entee
11y ago
I haven't used Go, but have spent a lot of time in Scala. Any statically typed language means increased pain with JSON. Static typing really has made me appreciate a well thought out JSON data model where each key in a document can hav
569.
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by
entee
11y ago
I think it's also that SF has fairly high income inequality, which means that their statistics for rental burden a prone to being misleading.
570.
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by
entee
11y ago
I don't think that abstraction is particularly useful because beyond extremely simple systems, approaching things from physics becomes 1.) not possible because we don't actually know enough and/or 2.) intractable because ther
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