e12e

5 ms·

1.
A unified evolutionary explanation of Parkinson's disease(pubmed.ncbi.nlm.nih.gov)
6 points by e12e 5d ago|1 comments
2.
by e12e 5d ago
Full text: https://www.pmdalliance.org/wp-content/uploads/2026/09/Farre...
3.
by e12e 6d ago
Nice touch to have the ability to run the model after upload. Like a cross between a Quine and a Morris worm for AI. But it'll only be truly fun when agents set up this for themselves, paying for the infrastructure by way of their only
4.
by e12e 9d ago
Wow, how did this not get discovered and fixed at the time of: https://www.cve.org/CVERecord?id=CVE-2007-0882 Might be a 32 year old bug, but it's practically also a 19 years old exploit? Ed: I'm confusing TFA wit
5.
by e12e 9d ago
In this case I suppose we can take the Ayatollah's word for it?
6.
by e12e 11d ago
I'd say mobile and desktop (from same html) would be more like css zen garden, than light/dark.
7.
by e12e 12d ago
Guess they need to hire an "idea guy" first?
8.
by e12e 12d ago
Animated SVG of a pelican shaving with Occam's razor?
9.
Usability Heuristics for User Interface Design (1994)(nngroup.com)
1 points by e12e 12d ago|0 comments
10.
by e12e 12d ago
I instantly thought of Nielsen's personal homepage - http://useit.com - which has moved on to a little softer and corporate design - but still linger in the Internet Archive: 1996: https://web.archive.org/we
11.
by e12e 12d ago
That's the beauty of asdf and then mise; they leverage existing solutions where possible, and unify how to get versioned runtimes for projects. Rust? rustup with mise, ruby? Precompiled when possible, otherwise ruby-build. Etc. I'
12.
by e12e 13d ago
> Why would you even use python without uv anymore Probably wouldn't: https://mise.jdx.dev/mise-cookbook/python.html#mise-uv > have a system python binary and virtual envs linked to it I'm not sure if y
13.
by e12e 16d ago
Object databases exist - they don't magically solve data(model|schema) migrations. See: https://zodb.org https://gemtalksystems.com/products/gs64/
14.
by e12e 16d ago
Equivalent to 10% year-to-year, every year - assuming 5 years. That is somewhat steep.
15.
by e12e 17d ago
Hm.. I just tried on my Google pixel 7 Pro (obviously very different display - OLED) - and certainly seems like the result of a test conversion pdf2djvu should be at home on an eink screen. Not sure if there's a simple way to test on t
16.
by e12e 18d ago
Nice. I keep wondering if these devices would play nicer with DjVu rather than pdfs and raster formats? https://djvu.sourceforge.net/
17.
by e12e 18d ago
You jest, but a wiki with a voting system might be a good fit for agents?
18.
by e12e 18d ago
You could always stay with phpbb - seems it still feels authentic: https://www.phpbb.com/community/viewtopic.php?f=14&t=2672425 (I'm guessing flarum.org makes more sense, though). A cursory search didn't
19.
by e12e 18d ago
Haven't the rogue openai agents already demonstrated that a wiki works well for this? Ed: for posterity https://www.reuters.com/world/europe/openai-agents-hijacked-...
20.
by e12e 18d ago
> Each of these stories will be written just for you Great, now you can ask for a feed and the AI will create an entire world of news filling your feed, your very own echo chamber.
21.
by e12e 20d ago
5 years is no age for an UI kit! ;-)
22.
by e12e 21d ago
I see that unison (file sync tool) seems to use: https://garrigue.github.io/lablgtk/ For Linux UI.
23.
by e12e 22d ago
I strongly disagree. Incidental complexity is the enemy good emergent properties of a system; security, auditability, stability, testability, maintainability...
24.
by e12e 22d ago
Useless depends on context here; I believe the idea is that each player gets a feeling of agency (they go in the order dictated by "their" luck, not leaving the decision to someone elses roll). The most pragmatic would probably be
25.
by e12e 22d ago
Except that as a sibling comment mentions; that generalizes to any size of group - for six players you could roll one d6, and have "that" player go first. But apparently the constraints are: every player rolls one die once.
26.
by e12e 23d ago
I think it's more about guaranteeing the whole sequence, rather than who goes first? At least for two players, if you use a two sided die (a coin), have player one win ties on ones, player two win ties of twos - and otherwise highest w
27.
by e12e 23d ago
Have you read Nelson?
28.
by e12e 23d ago
One reason I have some hope for this approach is that we start by removing complexity by going to a static web site first. We remove WordPress, database, configuration, templates - a lot of cruft. Then we can add it back as needed for keepi
29.
by e12e 23d ago
I'm not so sure the article is written with AI. I'd love to hear from the author on that.
30.
by e12e 23d ago
Interesting. This and the other posts I've seen about Delta seems to exist in that liminal space, were it's difficult to tell if the author has had a brilliant insight, that they struggle to convey to anyone who's not yet had

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