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daughart
searching PlanetScale…
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121.
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by
daughart
12y ago
The Affordable Healthcare Act was gigantic and created by morons, but by most metrics is improving the American healthcare system. The argument that the government can not act in a way that improves things, even if it is not the perfect sol
122.
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daughart
12y ago
At what point does "prioritization" effectively become blocking? People navigate away from websites that take a long time to load or have advertisements.
123.
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daughart
12y ago
That seems like something the USPTO would decide.
124.
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daughart
12y ago
You don't have to wonder, it's a scientific study. https://clinicaltrials.gov/show/NCT00543543 Sponsor: Merck Sharp & Dohme Corp Official Title: A Randomized, International, Double-Blinded (With In-House
125.
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daughart
12y ago
Are the quote marks, which are not present in the article title, really necessary here?
126.
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daughart
12y ago
What fields do you find having an academic "echo chamber"?
127.
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daughart
12y ago
Seems like a great plan, formalizing the well trodden and generally successful strategy of letting early adopters play with new tech early so that it's robust when mom and pop get their hands on it.
128.
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daughart
12y ago
I can't remember the details of this either, but as I recall it was done in liver because when you inject DNA into mice the liver basically filters it all out, so you get very high efficiency in the liver, but no where else!
129.
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daughart
12y ago
Sorry for the delay - there are many aspects of this that can be patented. Consider all the following inventions: - Alterations of the RNA that guides cutting (natural system uses two RNAs, which researchers fuse and alter for efficiency of
130.
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daughart
12y ago
It's not yet clear who will ultimately own this IP, of Doudna, Zhang, Church (in the US, the European patents have other contenders). Last I heard, Doudna and Zhang were set to have dueling lab notebooks. I wouldn't underestimate
131.
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daughart
12y ago
I image reviewers would typically know who the author is, or be able to discover it quickly, if they are in fact familiar enough with the field to meaningfully review the work. Similarly, authors can often guess who reviewers are based on t
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daughart
12y ago
I can't believe they have the nerve to call this professional writing.
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daughart
12y ago
I believe they're actually trying this as well.
134.
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daughart
12y ago
Just because they sell a 16GB version doesn't mean you had to buy it. Needing lots of space to record video is a niche anyway, like needing the iPod classic for large audio libraries. People store images, video, and music on cloud serv
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daughart
12y ago
Proteins misfold constantly, prion diseases are very rare, and creation of a novel prion would constitute a massive gain of function for a protein, therefore it is very unlikely to occur. Food shortage is a real problem that affects a billi
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daughart
12y ago
I agree with what you say about pesticides -- note I said BPA is not comparable with GMO, not that BPA is not comparable with pesticide. In this case, the genetically modified organism would be safe, but chemicals used to treat the organism
137.
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daughart
12y ago
The connectome project is interesting, useful, and ambitious, but the method they are using to generate these measurements, atomic scale microscopy (AFM, electron microscopy) are simply not scalable to the size of the human brain. We should
138.
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daughart
12y ago
Who cares even if it's not well controlled and changes many things? DNA mutates all the time with little effect. Every human born has a few novel mutations. There's no argument from this to a comparison with bioactive small molecu
139.
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daughart
12y ago
Thanks for the down-vote, but seriously do you have an argument here? Even Monsanto's "Roundup Ready" GMOs merely express a modified version of an enzyme that allows them to synthesize essential amino acids even in the presen
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daughart
12y ago
Chemicals like BPA and GMOs aren't equivalent in any sense.
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daughart
12y ago
I wonder what kinds of particles are re-introduced to the air between the 0.5 um size this vacuum filters and a traditional HEPA filter which excludes particles down to 0.3 um.
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daughart
12y ago
If you think college will be any better, you're dead wrong. It will be worse, because the punishments are greater, the rules are more ad hoc, and the administrators are both more knowledgable and more likely to be embarrassed in the mo
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daughart
12y ago
Hey, no problem. My issue is one of language itself. As someone who takes the english language very seriously, I don't ignore when someone makes the choice to use a particular word. Between our two comments, we have used the following
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daughart
12y ago
People don't call civil rights or women's rights "agendas," they call them "movements." Agenda is pejorative, pertaining to "underlying intentions"; whereas movement directly refers to the act of chan
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daughart
12y ago
The title strikes me as sexist, given the paper the author is discussing was first-authored by a woman.
146.
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daughart
12y ago
As for your first point, shotgun sequencing was not invented by Illumina. Shotgun sequencing, or sequencing many small fragments and then computationally reconstructing a larger contig, was first done in 1979, and later used by many groups
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daughart
12y ago
Was it really "well said"? It was a personal judgement followed by an unjustified assertion. It seems you merely agree with the comment, and have mistaken that with the author saying something well.
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daughart
12y ago
There's nothing to identify - it's a serum containing three monoclonal antibodies. These antibodies bind some viral proteins, preventing the virus from infecting new cells and spreading. To my knowledge there's no path from t
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daughart
12y ago
Anyone who says a full model of the brain is right around the corner is either a fool or a charlatan. The BRAIN initiative was a first start to _develop the technologies_ needed to take the measurements that would underly potentially explan
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by
daughart
12y ago
It doesn't help me at all, but that's because I'm not confused about this issue. If you drank large quantities of ultra pure water as defined in the article, without compensating for the loss of essential salts that would res
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