colingauvin

6 ms·

91.
by colingauvin 2mo ago
>1) Back then, even as a free user you'd be able to use the strongest model (even if with tight limits). Now, you need to pay to use Sol, and you need to pay to use Opus or Fable. It does seem fairly premium in that sense. Idk about
92.
by colingauvin 2mo ago
They must really be feeling the commoditization pressure. I'm not sure what the way out of this is, ChatGPT and Claude are still good products, but they are not necessarily premium products anymore. I expect a few things to happen in t
93.
by colingauvin 3mo ago
Is there any niche yet capitalism has not exploited to its fullest? Why do we think it wouldn't here?
94.
by colingauvin 3mo ago
Came here to comment this.
95.
by colingauvin 3mo ago
I had read that they were skipping 5.3 for 5.5 which was going to be ~3 T param.
96.
by colingauvin 3mo ago
I have found 27 to just be so much more coherent than 35: https://humanparadox.org/local-vs-frontier-benchmarks-for-my... It can complete multi-step tasks much better, and has a bit more curiosity.
97.
Local vs. Frontier: Benchmarks for My Digital Nervous System(humanparadox.org)
2 points by colingauvin 3mo ago|0 comments
98.
Local vs. Frontier: Benchmarks for My Digital Nervous System(humanparadox.org)
1 points by colingauvin 3mo ago|0 comments
99.
by colingauvin 3mo ago
OK really cool. I've been working on something similar but I started from the opposite direction. I first developed a database that pulls in data from as many personal sources as possible, and then runs it through a gradual annotation
100.
by colingauvin 3mo ago
Curious what you mean by proactive? Could you share a bit more?
101.
by colingauvin 3mo ago
This has nothing to do with what I am talking about.
102.
by colingauvin 3mo ago
There's plenty of information https://en.wikipedia.org/wiki/CASP
103.
by colingauvin 3mo ago
>DeepMind started developing AlphaFold in 2018. In 2020, it was recognized as a solution to humanity's 50-year-old "protein folding problem," which sought to answer how amino acids automatically fold into complex 3D shapes
104.
by colingauvin 3mo ago
I'm guessing that there are storage vendors that already do that - maybe like Liqid. But then you've got to traverse the NIC as well.
105.
by colingauvin 3mo ago
The problem is you'd have to traverse the PCI-E bus every transfer. Even with DMA it still has to physically get off the drive and onto the card. Even with the mythical PCI-E 6, if you had enough NVMEs to saturate, you have to do two t
106.
by colingauvin 3mo ago
There's a Python API that's "unofficial" but has worked well for me for ages. I've got it hooked up to NextCloud tables and it imports everything once a day. I've now got years of queryable metrics in NC.
107.
by colingauvin 3mo ago
Your comment is a stark reminder that I take for granted that the single biggest killer of human beings in history is simply something I don't have to think about. For some reason, I'd have thought there'd be no overlap betwe
108.
by colingauvin 3mo ago
Yes, which is why the immunological tests done in 2006 were not seen as conclusive. However, this time they found actual plasmodium DNA which suggests active infection at time of death. Including from two species, suggesting double infectio
109.
by colingauvin 3mo ago
>In order to use Ask Sage, the Army had access to 100,000,000 tokens as part of an annual subscription to an “enterprise pack.” Tokens represent a unit of output, either in text or image, from an LLM. For the Ask Sage tool, a single toke
110.
by colingauvin 3mo ago
Great piece. Was wondering whether to get an NVLink bridge for $500+ for my two A4500s for inference. This pretty much confirms it only really rescues you if you have nonsensical PCI-E topology.
111.
I thought I had a good homelab(humanparadox.org)
3 points by colingauvin 3mo ago|0 comments
112.
by colingauvin 3mo ago
I've had cells growing fine in 20 L Cytiva wave bags and then fail to grow in 20 L Sartorius wave bags. Anyone that tells you they know how a cell grows is lying to themselves :)
113.
by colingauvin 4mo ago
Yeah there's a point where I'd rather have the radiation than ultrasound.
114.
by colingauvin 4mo ago
The problem is there's an inverse relationship between penetration of the sound waves and the frequency.
115.
by colingauvin 4mo ago
Because it's completely meaningless without validation, and even with validation, not really any better than the state of the art protein generation models. Which are also mostly just nice to have because coming up with a candidate is
116.
by colingauvin 5mo ago
I'm not a MAGA or MAHA person. I just hate anecdotal pontificating about science. First of all, regarding the trans-fat discussion - in general, yes, keep trans fats low. However there are a couple important things to consider. One is
117.
Detecting Gunshots with a Watch Accelerometer(humanparadox.org)
2 points by colingauvin 6mo ago|0 comments
118.
by colingauvin 7mo ago
HN's blindspots never cease to amaze me. I am a structural biologist working in pharmaceutical design and this type of thing could be wildly useful (if it works).
119.
by colingauvin 7mo ago
Presumably they have unused compute in those hours and figure they may as well enable people to use it and get more invested into their ecosystem. What I wish Anthropic would do is be a lot more explicit about what windows apply when. Surel
120.
by colingauvin 11mo ago
>Vaccinated individuals were older than unvaccinated individuals (mean [SD] age, 38.0 [11.8] years vs 37.1 [11.4] years), more frequently women (11 688 603 [51.3%] vs 2 876 039 [48.5%]) and had more cardiometabolic comorbidities (2 126 2

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