cknizek

4 ms·

1.
by cknizek 5y ago
One of the main advantages of TD-NIRS is that the signal it's imaging is "electrical". Modalities like PET, BOLD fMRI, and CW-NIRS do depend upon saturation changes. For BOLD and CW-NIRS, it's the change in blood oxygen
2.
by cknizek 5y ago
I currently do research in MRI. I'm not entirely sure what you mean about IR technologies. Almost all medical imaging done today is done outside the skull. The only exception is ECoG, which is only medically used for patients with seve
3.
by cknizek 5y ago
Not a breakthrough. This technique has been known about for at least two decades. Most fNIRS uses the amplitude-based, continuous-wave modality to compare chromophore concentrations resulting from thermovascular coupling. This uses time-do
4.
by cknizek 5y ago
> I believe the "specialized brain regions" idea has been over-debunked. It was the source of so much woo woo in the late 20th century (are you right-brained or left-brained!?) that we've come to think it's complete b
5.
by cknizek 5y ago
Most NIRS systems use continuous-wave (CW) systems detecting blood oxygenation/chromophore concentration. I say this because, in the time domain, you're looking at 5-7 seconds to see changes in cerebral oxygenation. It's also
6.
by cknizek 5y ago
Very interesting implantation method. I never would've thought it possible to use a stent like this. I think the most valuable IP produced from Synchron will be implementing ECoG without an extremely expensive (and risky!) craniotomy.
7.
by cknizek 5y ago
This is a really hard problem. NIRS is already difficult; very weak signal, limited to <2 cm of cortical surface, and haemodynamic response is 5-7 seconds. I think it's definitely a useful imaging technique for certain (highly speci