cj

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by cj 2y ago
It's an overly harsh characterization of youth - as is much of the article. No need to say you have a character flaw just because you're 30 years old and didn't publish a book in your 20's. But I agree with the gist. Whe
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by cj 2y ago
Yes. In the same way addiction is a choice.
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by cj 2y ago
Specific part of the interview that talks about GLP-1 safety with DeFronzo and Attia: https://www.youtube.com/watch?v=QGIFdakceHM
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by cj 2y ago
I dont track it. I order instacart a couple times a month which costs $300 per order. Plus eating out. So about $1k or more a month. Single, live alone.
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by cj 2y ago
I’ll have to rewatch that video. Saw it a couple days ago and walked away with the opposite take. DeFronzo spent a whole lot of time heavily praising the generation of drugs (including the next generation in phase 2 trials) If there’s a spe
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by cj 2y ago
You can get wegovy generic for $299/mo and Zepbound generic for $399/mo currently through telemedicine via compounding pharmacies, without insurance.
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by cj 2y ago
I’ve been hyper aware of the muscle loss caveats and I think it’s the most important thing to know when starting the drug. You really need to prioritize protein intake and make sure your calorie deficit isn’t extreme. Losing too much weight
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by cj 2y ago
Luckily during the “shortage” you can currently get GLP-1’s in vials rather than injection pens. The brand name GLP’s you can’t control the dose. But when you get it in a vial from a compounding pharmacy you can inject however much or littl
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by cj 2y ago
After using them, I think GLP-1’s will eventually be rebranded as a weight management / weight maintenance drug rather than a weight loss drug in order to appeal to the masses. It’s a very interesting feeling to feel like you’re in ful
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by cj 2y ago
I started Tirzepatide 3-4 weeks ago. (Mostly as an experiment to understand the hype around GLP's... I don't have diabetes and only very slightly overweight at 20% body fat). Even at the lowest 2.5mg starter dose which you're
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by cj 2y ago
Flagging those comments is a small way everyone can help.
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by cj 2y ago
To be fair AWS also has quotas on NAT Gateways. Maximum 55k concurrent connections. After that, they make you deploy NAT gateways in other availability zones. And a max throughput of 10 Gbps. I imagine AWS would also tell you to deploy your
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by cj 2y ago
FWIW, my comment was from the perspective of a founder with no concern about my own status. But you’re probably right in other contexts.
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by cj 2y ago
Then again, it’s really frustrating to work at a company where you feel like you’re not allowed to point out problems because you might hurt someone’s feelings. I’ve been in situations where I see a major problem, while also having extremel
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by cj 2y ago
TLDR: She was having some health issues, so asked ChatGPT. It recommended she get bloodwork done, but she already had and got the results the night before but her doctor hadn't reviewed the results yet. So she uploaded the lab results
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by cj 2y ago
A quick Google shows 65% of public companies use calendar year as their FY. At our startup, it's even more complicated :) we use calendar year for official financial / business metrics, while our planning quarter is offset by 1 mo
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by cj 2y ago
Private Equity is well known for exploiting markets for profits without regard for much else. They will do things like enter a niche market, buy up all mom & pop shops (or in the case of ISP, even replace an existing monopoly), then onc
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by cj 2y ago
Meanwhile, in my neck of the woods in NY, we have Archtop Fiber who raised $350m from a private equity firm to build a fiber network and get everyone in our area to switch away from Comcast (only alternative). They're signing up entire
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by cj 2y ago
Maybe this is Grok’s “ChatGPT moment”. Similar to how OpenAI’s debut was with GPT-3.5 (not their first version) Debut in the sense that it’s something good enough that it’s getting mainstream attention.
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by cj 2y ago
After reading your comment, I was wondering "why do this study in the first place" if researchers are just pouring oil on an engine. The last sentence basically says that it's too difficult to get new drugs approved, so inste
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by cj 2y ago
You can achieve 2x leverage without the risk of margin calls by buying ETFs like SPUU (or SPXL, UPRO if you want 3x leverage).
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by cj 2y ago
I think we've only "gone too far" in the sense that cheap food also means unhealthy food, generally. Access to cheap food would be wonderful if it were healthy! Unfortunately the cheapest food is typically the worst food for
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by cj 2y ago
Source: https://nbaa.org/flight-department-administration/tax-issues... "Bonus depreciation" exists for cars too, but is capped around $20k. From quick reading, seems like the bonus depreciation for planes wa
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by cj 2y ago
Sometimes having humans in the loop is a feature, not a bug.
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by cj 2y ago
Anyone selling anything would want to remain crawlable if people use this to research something that could lead to a purchase.
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by cj 2y ago
ChatGPT is still benefitting from first mover advantage. Which they’ve leveraged to get to the position they’re at today. Over time, competitors catch up and first mover advantage melts away. I wouldn’t attribute OpenAI’s success to any ext
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by cj 2y ago
Touché. Although those stats about cannabis support the idea that it’s addictive. Daily or near daily use of nearly 50% of users sounds like it must be habit forming..
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by cj 2y ago
By the same logic, you could say “cigarettes aren’t addictive for most people”.
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by cj 2y ago
> 2. It isn't chemically addictive or habit-forming for most people. I've never understood why people claim it's not addictive when there are well established symptoms experienced when withdrawing. Disruption in sleep qual
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by cj 2y ago
Our company requires you have a LinkedIn because we’ve been burned by multiple engineers who accepted our offer and (months later) never actually quit their previous job. The common thread between people who have had multiple jobs at once h

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