caycep

18 ms·

421.
by caycep 2y ago
its not like I'm feeling super free of lock in when I'm using FB invites, partiful, or evite.
422.
by caycep 2y ago
Or....we could've been on the cusp of one of those Foundation/Asimov moments where our economy evolved beyond a manufacturing economy, with enough financial clout to...not actually need to be able to build our own ships?
423.
by caycep 2y ago
If your worldview is shaped by the P&L statements of the ranching industry, it seems you would be totally blind to the ecological benefits of wolves reintroduction. Denver residents probably weighed risks of higher costs of beef with th
424.
by caycep 2y ago
What kind of soured me on whether to recommend lecanumab in the clinic or not - the effect size and the slope, vs. the risk of hemorrhages/"ARIAS". I mean, if you're looking at an steady 0.8 pt difference in CRS-SB, but
425.
by caycep 2y ago
I think NIH does a cost of living adjustment.
426.
by caycep 2y ago
for biomedical, it is what your grant stipulates. I.e. I think way back when, K23's paid $98k for 75% time (or maybe 70%) and your institution agreed to pay the rest. Sometimes, they would actually pay you more to try and get close t
427.
by caycep 2y ago
it also depends on the lab. It's a very small world for various reasons and sometimes, there's a good combination between a PI and a hosting institution. Sometimes there's not. If the guy who's doing what you want to
428.
by caycep 2y ago
A lot of this is defined by the NIH, K23/R01 grant amounts specify what kind of salary they support and are kind of defined by the powers that be... UC system def has more overhead than usual, and there may be some cost-of-living adjus
429.
by caycep 2y ago
at this moment, what NIH? No study sections for grants since the inauguration...
430.
by caycep 2y ago
devil's advocate - is that not the very definition of scaling?
431.
by caycep 2y ago
So in the clinic - what we usually do is a detailed neuropsychology battery. Also a patient history, but the neuropsych does provide some quantitative measures. If there's clear amnestic memory loss, verbal fluency decline and visuals
432.
by caycep 2y ago
yeeeess...but when you look at the slope of the decline on the NEJM papers describing the clinical trials of lecanumab and donemumab...are you really slowing the decline?
433.
by caycep 2y ago
they have used Samsung before...maybe with middling results but if push came to shove, Samsung's fabs have been the backup I think.
434.
by caycep 2y ago
Rebellion and disruption is in Silicon Valley's nature. Especially against authoritarian right-wing figures (Traitorous 8) Especially now w/ renewed interest in fediverse and open source applications, now is the time for dissatis
435.
by caycep 2y ago
zheng he
436.
by caycep 2y ago
I think we're talking about 2 different things. movement/neuroplasticity/physical stimulation absolutely helps - hence PT, exercise classes, etc have being an important part of treatment My point is, though - the onset of dec
437.
by caycep 2y ago
our understanding Parkinson's is that it can be described as a control system issue. The part of the brain affected (at least initially) by the disease is part of a network (the basal ganglia/cerebellar network) that evaluates en
438.
by caycep 2y ago
I would say, maybe the other way around - gait is very much a cognitive task (think of all the compute power w/ reinforcement learning to get a robot to stand up or balance a stick). but it is probably a self-reinforcing cycle. That
439.
by caycep 2y ago
not sure - but it will likely be quicker because the software is sort of already built into current generation Medtronic devices. They are not trying to approve a whole new device, probably just the software that switches the device on&#x
440.
by caycep 2y ago
Keep in mind that paper cited isn't really the clinical trial that shows improvements in symptoms. It just shows their device works and can record LFP properly.... The actual clinical results so far shows that the gizmo with recording
441.
by caycep 2y ago
it's a scaling law for stocks!
442.
by caycep 2y ago
so the short story is - at the moment, the device is basically doing power spectra analysis w/ FFT and such from local field potential recordings, and only turning the device on when it's detecting a strong ~20 hz band. Helps w&#x
443.
by caycep 2y ago
For a while, tire shops wouldn't touch whatever Tesla had put on there. Whether it was actually specialized or there was some legalese w/ Tesla wheels that made them paranoid, I don't know. Drove friends who were Tesla owne
444.
by caycep 2y ago
I think it's not so much "maintenance" in stuff you're expected to do, the issue is when something goes wrong, the repair infrastructure isn't great. I.e. yea, the motor doesn't go wrong as often and there are
445.
by caycep 2y ago
i think eddie chang's paper on voice synthesizing is published, i forget if it was nature or neuron. it's prob on pubmed but i'm too lazy/sleepy to pull it. doris tsao and a number of collaborators have a few nice pape
446.
by caycep 2y ago
the one thing they need is better contacts/friends discovery tbh.
447.
by caycep 2y ago
My assumption is that old grants so far will still get paid out but any new grants (vital to any biomedical/biotech research career) is effectively on pause because NIH study sections that evaluate grant applications are canceled. If g
448.
Meta accused of pro-Trump bias after Democrat hashtag blocked on Instagram(msn.com)
6 points by caycep 2y ago|1 comments
449.
by caycep 2y ago
yeah I suppose that is also a main issue - i.e. whatever monetary model behind it needs to fund teams that addresses that point
450.
by caycep 2y ago
This is salient given policy moves by the CEO. My thoughts: -most of what you need is basically something similar to Facebook Groups (nowadays, I bookmark Facebook Groups for the 3 groups I follow, and skip the main feed, which is basic

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