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brandonb
searching PlanetScale…
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31 ms
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brandonb
1y ago
The latest evidence is that if you have ApoB and Lp(a), then particle sizes don't add any more information. This is the most recent research (published July 2025): https://academic.oup.com/eurheartj/article-abstrac
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brandonb
1y ago
Before getting a CAC scan, I'd probably do these tests first: * ApoB - about 20% of people with normal cholesterol results will have abnormal ApoB, and be at risk of heart disease. * Lp(a) - the strongest hereditary risk factor for hea
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Coronary artery calcium testing can reveal plaque in arteries, but is underused
(nytimes.com)
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brandonb
1y ago
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194 comments
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brandonb
1y ago
Super cool. An iPhone + Apple Watch generate about 40 distinct biomarkers of your data (resting heart rate, VO2max, workouts, sleep stages, sleep apnea risk, ECGs, and so on), but the ability to interpret them is very limited. I work on an
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Aging well according to a longevity researcher
(wbur.org)
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brandonb
1y ago
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The average Apple Watch user gets 49 minutes of deep sleep per night
(empirical.health)
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brandonb
1y ago
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1 comments
667.
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The Epic Battle for AI Talent–With Exploding Offers, Secret Deals and Tears
(wsj.com)
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brandonb
1y ago
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brandonb
1y ago
This is about Liquid Glass and Apple's design team. Wasn't clear from the title, but it's an interesting read.
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brandonb
1y ago
The advanced blood testing is helpful since about 1 in 5 people with a normal cholesterol will have elevated ApoB (and be at higher risk of heart disease). Getting sufficient potassium (lowers blood pressure) and not too much salt (raises b
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brandonb
1y ago
Elevated hs-CRP roughly doubles your risk of heart disease. Here's a few things people do to lower it: * Eat anti-inflammatory foods (e.g., blueberries) or use cooking techniques that produce fewer PAHs (e.g., braising or steaming rath
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brandonb
1y ago
Blood oxygen sensing is disabled in the US (due to the patent lawsuit with Massimo), but it still estimates VO2Max and sleep stages. VO2Max is based on GPS and heart rate sensor measurements, processed by a deep learning algorithm that uses
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brandonb
1y ago
You can get 90% of the benefit of these longevity clinics for 10% of the cost. First, advanced blood testing can cost <$200. Get ApoB and Lp(a) for heart health. hs-CRP for inflammation, A1c for diabetes, eGFR for kidney health, etc.
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brandonb
1y ago
The ACA was originally designed as a "three-legged stool" of nondiscrimination (insurance companies can't charge higher rates to sick people), the individual mandate, and subsidies. If you remove one of legs of the stool, the
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brandonb
1y ago
Yep -- ACA health insurance refers to the individual market.
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What’s on offer at a luxury Bay Area longevity clinic
(sfchronicle.com)
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brandonb
1y ago
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53 comments
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Why Whoop Stands Behind Blood Pressure Insights after FDA Warning
(whoop.com)
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brandonb
1y ago
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1 comments
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Don't Die of Heart Disease
(jared.xyz)
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brandonb
1y ago
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Apple Watch Ultra rumored to get high blood pressure detection
(9to5mac.com)
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brandonb
1y ago
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How Health Care Remade the U.S. Economy
(nytimes.com)
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brandonb
1y ago
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brandonb
1y ago
In the paper, they say they used the most recent 56 cases (from 2024–2025) as a holdout set. The majority of those cases happened after the o4 training cutoff of May 31, 2024.
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Operation Gold Rush, largest health care fraud bust in U.S. history
(washingtonpost.com)
29 points
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brandonb
1y ago
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10 comments
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The Path to Medical Superintelligence
(microsoft.ai)
10 points
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brandonb
1y ago
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8 comments
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Scientists discover off switch enzyme that could stop heart disease and diabetes
(sciencedaily.com)
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brandonb
1y ago
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684.
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brandonb
1y ago
TL;DR - this article is about ApoB. About 20% of people with normal cholesterol levels will have abnormal ApoB.
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The better cholesterol test you didn't know you needed
(washingtonpost.com)
4 points
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brandonb
1y ago
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1 comments
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Systemic Misalignment: Key Failures of AI Alignment Methods
(systemicmisalignment.com)
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brandonb
1y ago
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0 comments
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Accuracy of Apple Watch calorie counts
(empirical.health)
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brandonb
1y ago
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Removing race as a risk factor for cardiovascular disease
(peterattiamd.com)
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brandonb
1y ago
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Coronary atherosclerosis is a silent killer, but we have tools to stop it
(peterattiamd.com)
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brandonb
1y ago
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690.
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brandonb
1y ago
The confusion matrix linked above compares the Apple Watch to polysomnography equipment (which is the medical device used in a sleep lab). It doesn't _quite_ answer your question, since we're assuming the polysomnography equipment
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