bmau5

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by bmau5 4y ago
Definitely! Saliva is our best natural defense against cavities (and harmful bacteria), so we always recommend people who have struggled with cavities or dry mouth to consider options for increasing their saliva production, like chewing sug
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by bmau5 4y ago
My company is Bristle (bristlehealth.com), and we've found several things that look to cultivate healthy species so far. Hygiene plays a huge role (of course), but outside of that diet plays a large role. Cheese/dairy has been fou
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by bmau5 4y ago
We think this work is fascinating, but S. mutans isn’t the only species in the oral cavity capable of developing biofilms (nor is it the only cavity-causing species). I think this could be a great first step, but we’re currently more focuse
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by bmau5 4y ago
There is surprisingly little peer reviewed data on flossing, but we ran our own study on how flossing impacts the oral microbiome (surveying our users) and found that flossing incidence is correlated with reduced levels of gum disease, bad
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by bmau5 4y ago
The initial data on xylitol looks promising for reducing cavities! Particularly for stimulating saliva production (dry mouth is a large contributor to cavities risk) and as a sugar substitute that cavity-causing species can't digest in
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by bmau5 4y ago
I was referring to something more along the lines of what the above comment mentions (rebalancing with beneficial bacteria), but there are companies working on something like a dishwasher for teeth, one example is below: https://
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by bmau5 4y ago
Yes, thank you for catching this. As the comment above pointed out there will still be a need for removing larger food particles and hard to reach areas, but ideally with the addition of the mouthwash/intervention I'm mentioning w
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by bmau5 4y ago
That's it exactly. Some beneficial species play an active role in suppressing the pathogenic species (those that release acid or cause gum disease) and have other benefits including helping us break down dietary nitrate into nitric oxi
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by bmau5 4y ago
This is very interesting and has a lot of potential, especially for people who struggle to brush their teeth, but I think there's another future where brushing and flossing largely become obsolete. If we could develop a more effective
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by bmau5 4y ago
If it makes you feel better most people don't brush their teeth correctly (supposed to hold toothbrush at a 45 degree angle along the tooth/gum line). I think there's another future where brushing and flossing largely become
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An in-depth guide to oral probiotics(bristlehealth.com)
1 points by bmau5 4y ago|0 comments
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by bmau5 4y ago
Have these same regulations been applied to vaporizers? Anecdotally it seems these have taken over the majority of nicotine consumption in the US (along with Zyn pouches).
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Are electric toothbrushes better for your oral microbiome?(bristlehealth.com)
2 points by bmau5 4y ago|0 comments
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Variations in the oral microbiome are associated with depression in young adults(bristlehealth.com)
1 points by bmau5 4y ago|0 comments
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by bmau5 5y ago
A link to brushing and flossing correctly is below! In summary: - Brushing: Hold your toothbrush at a 45-degree angle. This is the best angle for cleaning both the surface of your teeth and inside the gumline (killing two birds with one sto
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The Oral-Gut Axis: Digestive disorders and the oral microbiome(bristlehealth.com)
2 points by bmau5 5y ago|0 comments
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Oral bacteria may influence cancer risk(bristlehealth.com)
3 points by bmau5 5y ago|0 comments
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Nitrate-sensitive oral microbiome interactions with brain function, heart health(sciencedirect.com)
1 points by bmau5 5y ago|0 comments
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by bmau5 5y ago
I was just looking for something like this. We've had several podcast recently, but sharing the entire clip to social media doesn't get the same engagement. Can't wait to try this. Thanks!
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CRISPR-Based Wearable Diagnostics Enable SARS-CoV-2 Detection Through Mask(genomeweb.com)
1 points by bmau5 5y ago|0 comments
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Oral microbiome as a source to enhance immunity against infectious diseases?(nature.com)
6 points by bmau5 5y ago|1 comments
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Scientists use optogenetics to help a blind patient see again(statnews.com)
199 points by bmau5 5y ago|14 comments
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Ginkgo Agrees to $17.5B Merger with Harry Sloan SPAC(bloomberg.com)
1 points by bmau5 5y ago|0 comments
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Three bacterial strains discovered on space station may help grow plants on Mars(eurekalert.org)
1 points by bmau5 6y ago|0 comments
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by bmau5 6y ago
Great question. We have a good idea of which species drive oral diseases, so we can tell if you have an overgrowth of these species. Our hope is through Bristle we can better characterize what constitutes a healthy microbiome so we can deve
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by bmau5 6y ago
It seems that more research is needed to confirm, but there are some studies and use cases where Xylitol seems to prevent tooth decay. This study has a great review[1] under "Xylitol and other polyols": https://www.ncbi
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by bmau5 6y ago
I'd just add that we're hoping to develop products that specifically reduce/eliminate oral pathogens while encouraging growth of probiotic species
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by bmau5 6y ago
I'm not familiar with her, but I agree she does seem objective and could have some useful input. We'll reach out. Thanks for sending!
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by bmau5 6y ago
Great question! We haven't looked into this ourselves yet, but a 2014 study found "that average partners have a more similar oral microbiota composition compared to unrelated individuals, with by far most pronounced similarity for
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by bmau5 6y ago
Thanks for sending this! One aspect of our test we're excited for is the ability to profile viruses, fungi, and bacteriophages since we use Shotgun Whole Genome Sequencing on the microbes (vs. a technology like 16s that only profiles a

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