biotinker

7 ms·

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by biotinker 1y ago
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by biotinker 1y ago
You found the authors' screen names and some other things they've made. That's not finding who they are. No one has signed their names, like their real names, to this. Who are they? Intelligence agents? For which country? The
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by biotinker 1y ago
The neat thing is that it it doesn't actually take much money to start up a new small organization if you want to. You can accomplish a remarkable amount with relatively little money. Some friends and I just started a tool library in C
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by biotinker 1y ago
You want home assistant, as other comments have noted. I have a reasonably complex set of behavior set up. I live in Bend, Oregon at 4000 feet. This is somewhere with hot sunny days, cold nights, and sometimes a lot of smoke. The effect on
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by biotinker 1y ago
We had a very unpleasant experience with AirBnB support when we stayed in a house that it turned out was infested by bats, which we discovered when we awoke to bats in the bedroom. For anyone unaware, bat bites are so small they are not det
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by biotinker 2y ago
And this is exactly why I like to buy AirGradient hardware. Your CO2 sensors are some of the best I've found for the price point, and I love your outdoor monitor as well. That said; I have started moving towards using SEN5x for a lot o
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by biotinker 2y ago
This isn't terribly different than the latest precision medicine in the US. For example, drugs like Keytruda can only be used in the presence or absence of certain genetic markers in the tumor. Most cutting edge immunotherapy is simila
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by biotinker 2y ago
This is interesting. The link they claim is that it's the iron in the meat, specifically in the form of Fe3+, which activates telomerase in colorectal cancer, advancing the cancer (or causing individual cancer cells to proliferate when
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by biotinker 2y ago
There are a lot of things that one can be in the absolute top of, and overall academic achievement need not be one of them. Speaking personally, when these articles come out, there are always a lot of comments about "I didn't real
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by biotinker 2y ago
> it inspired quite a few researchers to go into the study of parasites That was me! First I read Peeps by Scott Westerfeld when I was ~13, where ever odd numbered chapter is the story, and every even numbered chapter describes a diff
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by biotinker 2y ago
I don't see any connection between the Guardian and the recovered memory movement. Throughout this thread you have a bit of an insistence on narrowly defining memory in terms of the brain, i.e. memories that people have. In the field o
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by biotinker 2y ago
I'm not a domain expert in epigenetics, but in grad school for bioinformatics I did a bunch of research on nucleosome positioning[0] which is epigenetics-adjacent. "Epigenetic memory" is the term of art I was taught in grad s
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by biotinker 2y ago
It really depends where you are. Every municipality has different water. If you're downstream of a bunch of 19th-century dye factory locations, you may be better off with bottled water. If your tap water is of high quality, bottled wat
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by biotinker 2y ago
It's not possible to raise ethical beef at sufficient scale for a median piece of beef to be ethical, but it's absolutely possible to do so with chickens. It may be more profitable to raise chickens in inhumane conditions, but it
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by biotinker 2y ago
Ya know, I saw this a year ago, and was curious if it actually held up. After all, the amount of CO2 released by humans is only about 4% of all CO2 released, on an annual basis (730 gigatons all sources, ~30 gigatons by humans). But it&#x27
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by biotinker 2y ago
It's pretty bad career advice. If you're an indie app developer trying to make a living developing indie apps, then you need to care about design. If it's not your career, then it's great advice. A few years ago I had a
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by biotinker 3y ago
> most cancer is still diagnosed and treated in a "classical" manner. This is half-true at best. As someone who's helped build FDA-approved genomic tests for cancer treatment, a huge proportion of cancers (in the US) are t
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by biotinker 3y ago
Yeah I'm willing to bet there are more than one liquid biopsy tests submitted and likely to get approved. I worked at PGDx for ~5 years and wrote an appreciable chunk of their bioinformatics pipeline, though I moved on to a different i
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by biotinker 4y ago
> You don't need 500x coverage, trust me, please learn to design your experiments Maybe you don't need 500x coverage, and if you don't, then I'm glad you're not sequencing to that depth. But please don't t
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by biotinker 4y ago
BAM/CRAM reads are often mapped against a genome, but they needn't be. It's not uncommon in industry to convert FASTQ to unmapped BAM in order to only have a single file format, improve compression, etc.
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by biotinker 4y ago
Depends on the use case. If one is trying to broadly sequence a genome or exome, all of that is correct. For something like a liquid biopsy test that's looking for circulating tumor DNA, a given mutation may only exist in 0.5% of the r
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by biotinker 4y ago
These are FASTQ files[0], which are the actual raw bases read by the sequencer, and a quality score for each base. This is upstream of comparison to a known genome any other processing. You're correct that there's a lot of redunda
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by biotinker 4y ago
Tailscale is really, really doing a good job of taking all of the different secure remote networking tasks that have always been possible but self-managed and tedious, and wrapping it all in an automated, friendly interface. Every time they
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by biotinker 4y ago
At an orchard, or in the months of September and October. McIntosh are very difficult to keep properly, with age they will become mealy and bland. Same with many of its descendants, like Cortland. If you get to them within two weeks of bein
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by biotinker 4y ago
You're right about methane; that's much more difficult to find data on, though, especially with regard to how much would be released and at what point. But if those tipping points get hit, then nothing CO2 related will save us. Fe
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by biotinker 4y ago
Of the amount of CO2 released each year by humans (~30gt), only about half persists in the atmosphere. The other half is re-absorbed by the biosphere. This is based on estimated total biosphere emissions, estimated human emissions, and annu
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by biotinker 4y ago
The whole system is built on gRPC, and everything is open source aside from our cloud app itself. So yes, you can run your own server, you can have multiple robots talking to one another, etc, all on your own network with no outside communi
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What Do You Want to Build?(viam.com)
10 points by biotinker 4y ago|0 comments
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by biotinker 4y ago
Subtitle: "Instead of arguing Utilitarianism vs Deontology, everyone should just follow Virtue Ethics"
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by biotinker 4y ago
Golden Delicious and Red Delicious are not related to one another except in name (and in the sense that all apples are related). They do not have a known common lineage.

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