bglazer

14 ms·

151.
by bglazer 2y ago
My favorite part of Workday applications is the fixed list for “field of study”, which doesn’t include my field of study or an “other” option. Or maybe its the “autofill from resume” which always, always fails in different unexpected ways.
152.
by bglazer 2y ago
I’m not religious but it’s as close to a spiritual experience as I’ll ever have. It’s the feeling of being confronted with something very immediate but absolutely larger than I’ll ever be able to comprehend
153.
by bglazer 2y ago
Computation is really integrated through every scale of cellular systems. Individual proteins are capable of basic computation which are then integrated into regulatory circuits, epigenetics, and cellular behavior. Pdf: “Protein molecules a
154.
by bglazer 2y ago
It's a virus that adds a bit of genetic code to cells in the ear. The new genetic code is the instructions for the protein that is broken in the the little girl (and other similar patients). The cell can then use the newly introduced D
155.
by bglazer 2y ago
No, this is an adeno-associated virus (AAV) gene insertion. An engineered version of a naturally occurring virus inserts a working copy of the OTOH gene into the genome of cells in the inner ear. EDIT: I was incorrect. It seems that the vir
156.
by bglazer 2y ago
This headline does not make much sense. What the article describes is generative AI for molecular design. That’s a perfectly valid and useful thing to do, but it’s not drug design. Drugs are molecules that affect specific targets in human p
157.
by bglazer 2y ago
Somewhat off-topic, but has anyone tried training a random forest at LLM scale? Like an RF with millions of trees and billions of branches? My intuition says it could be much more efficient on CPUs, provided it works at all.
158.
Explosively pumped flux compression generator(en.wikipedia.org)
27 points by bglazer 2y ago|13 comments
159.
by bglazer 2y ago
Can anyone explain what self-alignment means here?
160.
by bglazer 2y ago
Principal investigator. It’s what phd students call their academic advisor/boss during graduate school
161.
by bglazer 2y ago
Is this actually true?
162.
by bglazer 2y ago
Their website says .95 Mach and 9Gs… in simulation. It’s definitely going to be high powered.
163.
by bglazer 2y ago
First the search space is way too large for brute force enumeration. We’re talking like 10^300 combinations. Also the hard part isn’t just listing amino acid sequences, its finding ones that do what you want them to. The only way to figure
164.
by bglazer 2y ago
I have a hot take that biology is just too complex and complicated for humans to truly understand. We have the cognitive ability to reason about the relationships between about 150 humans. So, if thats a plausible upper limit for how many g
165.
by bglazer 2y ago
You might enjoy this course form Yale. It’s called Ecology, Evolution, and Behavior. I listened to it as a podcast several years ago. It was my first introduction to “real”, not high school, biology, and it blew my mind. The material is pre
166.
by bglazer 2y ago
Yep, model checkers are one of the more powerful tools for working with Boolean models. You might find some of the work from Jasmine Fisher's lab interesting, especially when she was at Microsoft Research. My take on model checking for
167.
by bglazer 2y ago
Thanks for the reply
168.
by bglazer 2y ago
I mean you did join a government organization that provided a (more or less) guaranteed job and training. Also, this is a genuine question, how much of the chaos in your life was due to financial hardship? Do you think just having more mone
169.
by bglazer 2y ago
Yep, they’re just next state equations with boolean states. It is indeed very general. The interesting bit is that they typically have lots of feedback loops, which leads to behavior that’s really difficult to predict.
170.
by bglazer 2y ago
The first paper I wrote in my PhD was about how we could use reinforcement learning to automatically find models that have trap space (attractor) behavior that matched experimental observations. A big bottle-neck in that process is figuring
171.
by bglazer 2y ago
The most common use of Boolean models is simulating biological systems, i.e. genes and proteins interacting with each other. Trap spaces are the steady states of the model. So, if you start the model in a random state then you're guara
172.
by bglazer 2y ago
What’s the conclusion here? Basically, the last paragraph says pundits should talk to different sources, and that they should “keep the interests of the nation” in mind. He concludes by saying some vaguely ominous thing about politics not m
173.
by bglazer 2y ago
They telegraphed the attack by launching a wave of drones that took hours to arrive. One theory is that they were trying to do a combined drone and missile strike to increase the load on Israeli defenses. If so, it didn’t work at all. So, a
174.
by bglazer 2y ago
MicroCT scanners are really amazing pieces of technology. There's a professor from the University of Granada that posts absolutely incredible 3d MicroCT scans of insects. It really shows that even the lowliest, most inconspicuous beetl
175.
by bglazer 3y ago
Fun fact about RealPage that's not mentioned in the article: Jeffrey Roper is the guy who created RealPage's price setting product (YieldStar). Jeffrey Roper's previous professional experience was building a similar product f
176.
A Tantalizing 'Hint' That Astronomers Got Dark Energy All Wrong(nytimes.com)
5 points by bglazer 3y ago|0 comments
177.
by bglazer 3y ago
That makes sense, I figured it was related to some of the statistics work in ecology estimating species count from a limited sample.
178.
by bglazer 3y ago
These are the best results that I've gotten from an AI research assistant. I really don't mind the long latency, in fact, I think it's a fundamentally better way of interacting with this kind of LLM based tool. Like the laten
179.
by bglazer 3y ago
It’s telling that your examples are theoretical physics, math, and computer science. You should visit a lab that does actual experiments. I don’t think anyone is doing cryo electron microscopy in their spare time. Most science just takes a
180.
by bglazer 3y ago
I’m finishing a phd now and this is very good advice, especially point number 1. There are a lot of good, technically fascinating ideas out there. Only a subset of those are interesting to other researchers in your field. As an early career

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