benmaraschino

9 ms·

1.
by benmaraschino 7mo ago
You (and others) may enjoy going down the rabbit hole of universality. Terence Tao has a nice survey article on this which might be a good place to start: https://direct.mit.edu/daed/article/141/3/23&#x2F
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by benmaraschino 7mo ago
They did. Check out Figure 2 in the paper.
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by benmaraschino 7mo ago
They used a crossover design, so each subject served as their own control. Not a bad choice for trials like this as you gain a lot of statistical power with fewer participants than a parallel-arm, non-crossover design.
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by benmaraschino 2y ago
This book isn’t specifically about how to best support a blind child, but it might still be of interest. https://en.wikipedia.org/wiki/Far_from_the_Tree Either way, I hope for nothing but the best for you, your son, an
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by benmaraschino 6y ago
Counterpoint: the investigators used a crossover design, where each participant acts as their own control. Since within-subject variation <<< between-subject variation, this makes the effective sample size much, much higher than it
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by benmaraschino 6y ago
Yes, this is a part of the problem. This is also why it’s hard to interpret the results of studies like this. Without knowing more about the methodology, it’s possible that a lot of the apparent variation in cost arises from different ways
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by benmaraschino 6y ago
There are payment models like this in use already. Look into capitation and accountable care organizations.
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by benmaraschino 6y ago
The causation arguably goes in the other direction too. You can't make money if you're unhealthy at baseline. Nor can you as easily acquire more education or new skills.
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by benmaraschino 6y ago
Yup. We don't know the full details, and I don't want to speculate any more than I have to, but it needs to be pointed out that subdural/epidural hematomas caused by head injury can take some time to kill you. Remember Natash
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by benmaraschino 6y ago
Aside from the fact that this demonstration was limited to the semi-public atrium of the Hart Senate Office Building—historically, a location where many such demonstrations have been held, and all peacefully, to my knowledge—I'm willin
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by benmaraschino 6y ago
The issue with coatings and lubricants is that you’d need to use a nontrivial amount for them to be effective, and that means the patient is at risk of aspirating the substance. That happens, and boom, you’ve got aspiration pneumonia. Even
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by benmaraschino 6y ago
One of these "studies" is a 2-page Google Doc with no real data. Another is the discredited Raoult study, which is under investigation by the journal [1]. Another study cited is also by Raoult's team. The Brazil study (ref. 2
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by benmaraschino 6y ago
It’s nowhere near as difficult to make as the article may imply, though. Yes, that first-generation route is quite a doozy, involving some harsh conditions (multiple steps at -78° C, which is actually not as difficult to carry out at the be
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by benmaraschino 7y ago
Unfortunately, this is a really bad analysis, because, for one, the author assumes in his model that the total number of infections won't change as the result of greater social distancing. But distancing will have an effect on the numb
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by benmaraschino 7y ago
You the nail right on the head. Especially regarding VALI. Personally, I’d also be worried about any residues in the system (e.g. lubricants, grease, etc.) being blown into your lungs. That’d be an excellent recipe for a hellish aspiration
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by benmaraschino 7y ago
> Owning in a high cost of living geographic area is not a right, it is a luxury obtained mostly by luck This is kind of a weird take. Whether someone can afford to fulfill as basic of a need as housing shouldn't be about luck, no
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by benmaraschino 7y ago
Likely there would be little to no difference, because as it turns out, outcome risk is an awful predictor of benefit, especially among high-risk patients. Many high-risk patients will be readmitted to the hospital anyway, no matter how muc
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by benmaraschino 7y ago
It’s not practical. Patients on ECMO require anticoagulation, as do patients on cardiopulmonary bypass. This is a problem common to all systems which expose blood to foreign surfaces and pass it through pumps. Your hypothetical anticoagulat
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by benmaraschino 7y ago
Agreed. The point of criticism that the authors didn’t include all relevant models is among the lowest of the low-hanging fruit I can imagine one picking. And while the process of peer review isn’t without its flaws, I can also imagine that
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by benmaraschino 7y ago
Exhibit A: Vimovo. One pill, consisting of two drugs that have been around for decades, and are available over the counter at any pharmacy. If bought separately, a month’s supply of these drugs would run you maybe $40, at most. Vimovo, on t
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by benmaraschino 7y ago
The way many clinical research groups are structured (unfortunately) precludes code review, and to some extent, version control. Often for projects like the one referenced in the OP you'll have just one statistical programmer working w
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by benmaraschino 7y ago
Not the OP, but I work on similar problems, albeit in a different setting (healthcare, millions+ of patients). The gist is that you have to bake experimental design into the deployment of your ML model, but in many cases a simple RCT or A&#
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by benmaraschino 7y ago
No way. It's not even close. And I say this as a PhD candidate in one of these fields at Stanford. Grad school is what you make of it, to a large extent. There's definitely toxicity, but it's not as systematic or ritualized t
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by benmaraschino 7y ago
Well, at the end of the day, you can never really be sure of strongly ignorable treatment assignment/unconfoundedness, no matter what problem you’re working on. Especially if you’re an economist or an epidemiologist working with data t
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by benmaraschino 7y ago
While it’s often an ostensibly appealing point of criticism, it’s important to note that sample size is just one aspect of study design—the investigators used a crossover design, which substantially increases statistical power. In the Metho
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by benmaraschino 7y ago
Not always true. That OOP max often only applies to providers who are considered in-network for your insurance plan. Oftentimes, there's no way to guarantee that all the providers you see during an episode of care will be in-network;
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by benmaraschino 7y ago
Denmark's healthcare system tried to implement Epic nationally, and if this article is anything to go by, it didn't go so well: https://www.politico.com/story/2019/06/06/epic-denmark-healt... E
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by benmaraschino 8y ago
Comparison shopping arguably isn’t the intended purpose of advance care directives—which, FYI, can only go into force if the person is legally incapitated, and being in pain, however extreme, is a grey area as I’m sure you could make the ca
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by benmaraschino 8y ago
I honestly don’t get it either. Medicare takes care of some of the sickest and most complex patients—the elderly and those with ESRD—and manages to do it with an administrative overhead of 2%, compared to 17% for private insurers, and appea
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by benmaraschino 8y ago
While Epic produces the database/electronic health record system, the hospital or health system ultimately owns the data. AFAIK patient data don’t sit on Epic’s own servers outside of some research/pilot initiatives. (Source: my p

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