apathy

30 ms·

211.
by apathy 10y ago
This is fantastic. My only concern is that, after the last election's results, it's not clear to me whether enough members of the electorate are willing to vote in their own best interests (rather than "cheering" for th
212.
by apathy 10y ago
Interested to hear how this is "precision oncology". Do the 5hmC patterns predict treatment response? (Spoiler: no, because this was retrospective; need a trial to validate) Do they provide information above and beyond IDH or co
213.
by apathy 10y ago
so the whole thing was just an exercise in choosing a cut point? It would seem like you might want to revisit this sort of thing every now and then, what fer since both web "frameworks", your parsing code, and CPU hardware change
214.
by apathy 10y ago
this is strange -- why is there a little bit of Python in the middle of an R implementation/prototyping?
215.
by apathy 10y ago
To be honest it's really only adult trials that are fucked. Well, those and rare diseases with a noisy yet ignorant "advocacy" lobby ("We won't have to pay if the drug doesn't work, the magical Insurance Fairy
216.
by apathy 10y ago
ah, Begley, such a saint: http://www.nature.com/nature/journal/v497/n7450/full/497433a... This is the guy that published the irreproducible results paper whose results were (of course) irreproducibl
217.
by apathy 10y ago
> If you don't have access Where would you not have access to a PLoS paper? The entire company is dedicated to open-access publishing. First link in Google pops up the PDF, FWIW. http://robotics.cs.tamu.edu/RSS2015N
218.
by apathy 10y ago
Not just diabetes, it appears to enhance the efficacy (such as it is) of cytotoxic chemotherapy as well. Not sure how someone would actually file an infringement lawsuit for not eating, though. This therapy has a little tiny bit of prior a
219.
by apathy 10y ago
fyi: re: "I don't really know if the medical field has any use for text mining, graph processing and the like." It does. Although the graph processing use cases that I've seen recently (and their developers) are better
220.
by apathy 10y ago
Actually I'm pretty sure DHL (Destroy, Hide & Lose) has a patent on that, so, not without paying royalties.
221.
by apathy 10y ago
Disclaimer: not only did I upvote you but I totally agree with you. HOWEVER, it's not clear to me whether people are comprehending the tradeoff you describe. That is CRITICAL. I keep hearing about Hadoop and Spark for graphs and mode
222.
by apathy 10y ago
Why do I have to be "for" or "against" anything? Why can't people evaluate the evidence and THEN decide?!? It feels like these sorts of things make polarization worse.
223.
by apathy 10y ago
> too many shortcuts taken in CLIA labs and the LDT space. jesus fuck, this is NOT what I need to hear as we push our salvage therapy companion biomarker into a 160 patient trial. then again I work in pediatrics these days and nobody eve
224.
by apathy 10y ago
if it's structured you probably don't need Hadoop. Stuff it in BigQuery or RedShift and be done with it. Hadoop is a marvelous way to make simple things complicated. Look at what Google does internally (and has been doing intern
225.
by apathy 10y ago
It's true, SCIF and compartmentalization eventually demands an air gap between TS-SCI and the rest of the world. Eventually everything interesting gets tainted. Hence the suggestion never to run anything with any more ACLs than necessa
226.
by apathy 10y ago
This is actually a great idea from Perl. Essentially an anti-monad. Somehow it doesn't surprise me that the php proposal is inactive (asterisk). I haven't the foggiest idea what people do today in php but if they don't used
227.
by apathy 10y ago
Keeps my consulting going ;-) In all seriousness I've taught postdocs who were willing to learn everything from Python to C++/MPI to assembler. The key is just to be intellectually curious and enjoy solving problems. R is very of
228.
by apathy 10y ago
have them write packages and turn in the vignette. problem solved
229.
by apathy 10y ago
dplyr abstracts away so much bullshit... they're not even playing the same sport. Pandas brought R-style data.frames to Python; dplyr makes databases, data.tables, etc. all behave the same. Out-of-memory, in-memory, all the abstracti
230.
by apathy 10y ago
GAMs, BARTs, extensions to the Cox model, etc.
231.
by apathy 10y ago
I did -- it looks like 3000 people were killed in it. Less than the myths would have you believe, but still a lot of people to kill on purpose (especially if they're not actively trying to kill you). I'm just not a big fan of us
232.
by apathy 10y ago
Absolutely true, and although I did pay for Overleaf at first, I stopped paying when I realized I didn't need the for-pay features anyhow. They made a conscious decision to focus on internal development and I'm OK with that -- Go
233.
by apathy 10y ago
Three cheers for secular humanism! A side benefit of entire populations grown weary of fairy tales, now the land formerly reserved for tax-exempt politicking can be repurposed for economic growth that benefits even unbelievers. The irony of
234.
by apathy 10y ago
Please share it with everyone who might benefit. Be the change you want to see in the world ;-) (Ha ha only serious. Being an idealist made me cynical. Then it brought me back again. In the end we only have each other, those who we live and
235.
by apathy 10y ago
Overleaf.com is really nice too, if you work with others (e.g. on academic papers). The most painless papers I've ever written were with other competent people using LaTeX and overleaf. ShareLatex is good too, I'm not sure if yo
236.
by apathy 10y ago
Everyone in academia should internalize it
237.
by apathy 10y ago
First rule: Institutions can never love you back. http://clincancerres.aacrjournals.org/content/5/9/2281 Simone's Maxims are possibly the best piece of career advice anyone ever gave me. At least she&#x2
238.
by apathy 10y ago
Is it common to accuse a student of plagiarism without, oh, I don't know, actual evidence ? You know, like the fruits of searching Google for five seconds to try and locate "the offending phrase"? What kind of a fucking foss
239.
by apathy 10y ago
> a disproportionate number of the targets of censorship on Twitter are of a certain political influence. Yeah see I don't worry so much about this. I purposely follow people with whom I disagree (but who are well spoken) on Twitte
240.
by apathy 10y ago
Also, turning around an aircraft carrier (e.g. a public company with thousands of employees) is a whole hell of a lot harder than turning around a tugboat (private company) or a raft (a startup with 10 people in a room). Advice to the OP: d

More ›