aliasEli

40 ms·

421.
by aliasEli 5y ago
How do you handle any medical claims by the manufacturer? Few consumers will be able to determine independently whether or not such claims are justified. How should consumers judge the quality of the research into this drug? How should they
422.
by aliasEli 5y ago
AFAIK there is no reliable non-invasive procedure to determine the amount of plaques in the brain. So it will be difficult to make hard statements about the effect of potential drugs on the plaques. Also we are not really very interested in
423.
by aliasEli 5y ago
Data for 2019 [0]: > NHE grew 4.6% to $3.8 trillion in 2019, or $11,582 per person, and accounted for 17.7% of Gross Domestic Product (GDP). > Prescription drug spending increased 5.7% to $369.7 billion in 2019, faster than the 3.8% g
424.
by aliasEli 5y ago
But i would expect that the cost of these medicines are quite a bit lower. After all water is pretty cheap. Most of them are just placebo's, but then again placebo's really do work.
425.
by aliasEli 5y ago
Just the fact that we have not been able to find a medicine to reduce plaques does not imply that "The amyloid hypothesis for Alzheimer's is WRONG." Amyloid plaques are correlated with Alzheimer. AFAIK it is still an open que
426.
by aliasEli 5y ago
Could you perhaps change the title? I have read several articles about it but I could not remember its name. It will probably get more views if you include "Alzheimer" in the title.
427.
by aliasEli 5y ago
One of the very few things that most people can agree upon, is that SmallTalk is object-oriented. SmallTalk definitely has closures. Also Java has them.
428.
by aliasEli 5y ago
> Both lambda calculus and Turing machines are computationally less powerful than Actors. Do you have a reference for that?
429.
by aliasEli 5y ago
In general it is expensive. In most cases you will need experts that need knowledge of both system A and system B. Those people are more difficult to find. Also you have a higher chance of errors due to confusion between the two systems.
430.
by aliasEli 5y ago
When your site can expect visitors from all around the world you need a CDN that also has a world wide presence. Using a CDN can have a pretty big impact on the performance of your site, and it is well known that users avoid sites that are
431.
by aliasEli 5y ago
This looks a quite likely scenario. But then we still don't know what they fixed, was is the incorrect configuration or the underlying bug? I would expect the former instead of the latter, because it is probably not very difficult or d
432.
by aliasEli 5y ago
Yes, that might happen. But the only way to avoid that is to give each customer its own private hardware, which seems prohibitively expensive (and may not even prevent all failure sources).
433.
by aliasEli 5y ago
Don't you ever use public transportation? Most larger European cities have quite acceptable transportation. Also one of the reasons it takes longer is probably that there far more cars on the road and everybody is using their car even
434.
by aliasEli 5y ago
It depends a lot on the country you are in. In the Netherlands pedestrians and cyclists normally get priority, because the car is making a right turn while the other groups are continuing in a straight fashion. What probably also helps is t
435.
by aliasEli 5y ago
I you want to see a country that appears to be extremely fond of roundabouts, you should come to the Netherlands. In the past 20 years a high proportion of crossings has been replaced by roundabouts. We do not always have sufficient space,
436.
by aliasEli 5y ago
> Much more commonly plants are limited by access to nutrients and sunlight. In many parts of the world water is also pretty important. We know that global warming will change global air currents, but is pretty difficult to predict how t
437.
by aliasEli 5y ago
The NSA is probably the biggest employer of mathematicians in the world. Unfortunately they don't publish very frequently.
438.
by aliasEli 5y ago
Saving only the tests is completely nonsensical. Even with 100% code coverage, tests will only cover a tiny fraction of the programs behavior. The original program of course fully describes its behavior. If you are lucky you might even have
439.
by aliasEli 5y ago
> The largest number reliably factored by Shor's algorithm is 21 which was factored in 2012.[0] So for the time being quantum is not a real thread to cryptography and there sound technical reasons to assume that it never will be. [0
440.
by aliasEli 5y ago
A nice categorization of bugs. Most of them looked horribly familiar.
441.
by aliasEli 5y ago
The article appears to be a tongue-in-cheek argument for Test Driven Design, but it does not give a very balanced view of the pro's and con's. I have been in teams that tried to use it. Our general conclusion was that it invites y
442.
by aliasEli 5y ago
An obvious solution is to have more CDN providers. But because this requires big investments this is not very likely to happen spontaneously.
443.
by aliasEli 5y ago
I really don't see the problem here. Journalists and spies have a lot in common, so why shouldn't they learn from each other?
444.
by aliasEli 5y ago
One of the main reasons for unrealistic expectations is that most people really underestimate our own biological hardware. They assume that what is easy for us should also be easy for machine. They ignore the fact that there was a very long
445.
by aliasEli 5y ago
That is probably by design. Many front-end collisions are with stationary objects and the front-end of your car has been designed to absorb as much of that energy as possible.
446.
by aliasEli 5y ago
It is a nice overview article. But in spite of its optimistic title, it also makes it very clear that there are still lots of unsolved problems.
447.
by aliasEli 5y ago
How common are such parking space requirements in the US? It does not appear to be real free market approach why should not everybody have to pay for their parking spaces?
448.
by aliasEli 5y ago
All articles about fusion and magic should contain a reference to Cold Fusion [0] because that was really magical. [0] https://en.wikipedia.org/wiki/Cold_fusion
449.
by aliasEli 5y ago
They could argue that they were entrapped by the FBI, but that argument does seem to carry much weight in the USA nowadays. [0] https://en.wikipedia.org/wiki/Entrapment
450.
by aliasEli 5y ago
By far the most likely cause for the next pandemic is transmission from animals. By just focusing on labs you do not do anything substantial to prevent that pandemic.

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