4 ms·
Just the fact that we have not been able to find a medicine to reduce plaques does not imply that "The amyloid hypothesis for Alzheimer's is WRONG." Amyloid p
by aliasEli 5y ago
Just the fact that we have not been able to find a medicine to reduce plaques does not imply that
"The amyloid hypothesis for Alzheimer's is WRONG."
Amyloid plaques are correlated with Alzheimer. AFAIK it is still an open question if they play a role in the causation of the symptoms.
- bsder 5y agoAmyloid plaques seem to be correlated with lots of things--they seem to be a general response to damage to the brain. Almost all of the evidence seems to point that amyloid plaques are not causative with Alzheimer's. The fact that every single drug (including this one!) targeting amyloid plaques (some of which are actually effective at reducing amyloid plaques) has failed to do anything for Alzheimer's suggests that amyloid plaques are the WRONG target.