akkawwakka

7 ms·

1.
by akkawwakka 4y ago
Grew up dodging scores of it as they flew over our bass boat flying down the backwaters of the Mississippi. Twenty years ago I wouldn’t be able to find a single person who had ever eaten it and I’m not sure that’s any different today, which
2.
by akkawwakka 4y ago
The conversation around this could benefit from more precise language. Long lived immunity against severe disease, driven by the T cell response against epitopes that are generally well preserved (>80% for spike protein, ~98% for non spi
3.
by akkawwakka 4y ago
We are preventing development of serious disease with the vaccine. At the end of the day, that’s what should count.
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by akkawwakka 4y ago
Immunity to infection ≠ immunity to serious disease. The epitopes that drive long-lived memory are fairly well conserved.
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by akkawwakka 5y ago
You might be happy with something like VSCode + sourcekit-lsp once that combo gets more mature.
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by akkawwakka 5y ago
First, this proves that investment in drug discovery for all pandemic potential viruses, fueled by basic science research, needs to be a huge priority going forward. Imagine having antivirals on the shelf for the Coronas, Avian influenza, N
7.
by akkawwakka 5y ago
I recommend checking out Juan Browne’s video [1] that contrasts studies from the aviation world and one from the telecoms. Spoiler: the former brings more technical analysis than the latter. I’d love to know why the FAA is ‘rolling over’ to
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by akkawwakka 5y ago
This should be a surprise to no one. The vaccines are designed to prevent serious disease, hospitalization, and death. Unfortunately the media has harmfully claimed that the vaccines are “less effective against Omicron” because of the reduc
9.
by akkawwakka 5y ago
This is a bit of a tangent, but this is emblematic of the fact that, beyond Xcode Cloud, the Apple Developer Tools team seems more excited to work on toys like Swift Playgrounds than make the Apple platform development experience better and
10.
by akkawwakka 5y ago
Yes, they are. Strap one on and fly a fighter jet in Flight Sim 2020 and tell me they aren’t. But they are fatiguing, unflattering, and uncomfortable, even for 20 or 30 minutes worth of usage. Maybe in 10 years when the software stacks are
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by akkawwakka 5y ago
Prosecuting FSD claims, historical or present, seems like a slam-dunk case for the FTC…
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by akkawwakka 5y ago
Parsec is outstanding for this use case, it’s basically a roll-your-own Stadia. Dunno what its future will be now that it was acquired by Unity
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by akkawwakka 5y ago
Understanding (confirmation?) of memory T cell immunity might also tamp down the popular concerns regarding waning / lowering of of circulating B antibody levels. It seems we’re champing at the bit to get boosters going for non-immune
14.
by akkawwakka 5y ago
Easy to scoff at an obvious headline, but SARS-CoV-2 may very well be endemic now. Going forward pandemic preparedness will no longer be reserved for the Fortune 5s or 50s. New construction for a while at least will hopefully consider biose
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by akkawwakka 5y ago
It’s definitely a pro-social, social platform. It shows that you don’t have to rely on polarizing or adversarial content to drive engagement (_ cough , like Facebook & Twitter cough )
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by akkawwakka 5y ago
The moderation is a definite net positive. Though those with political viewpoints opposite a given user and anti-vaxxers have abused the stringent moderation to wantonly get videos taken down or users’ live stream disabled. Growing pains.
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by akkawwakka 5y ago
Calico seems like a vestige of Larry’s Google. Hope Ruth doesn’t Loon it. https://killedbygoogle.com
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by akkawwakka 5y ago
It’s definitely a fount of creativity! Maybe it’s all the Gen Zers but it’s also the least toxic social network around. There’s so much joyful content there.
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by akkawwakka 5y ago
Agreed. They can do it nicely, too, by extending the "Handoff" concept to further replicate application state between macOS and iPad OS apps. It would probably be an opt-in thing for apps, but even without any fancy state replicat
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by akkawwakka 5y ago
ISDN still must be in heavy use in radio. Sirius XM has been using hardware IP codecs since the pandemic began, and once a three hour show you might hear garbled audio for a few seconds.
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by akkawwakka 6y ago
No. The RNA still needs to be fit in a lipid nanoparticle which is Moderna and BioNTech’s secret sauce.
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by akkawwakka 6y ago
Manipulating the source code leads to invoking the Swift compiler to generate the information required to drive the rich editing experience. I have found SourceKit’s performance in complex projects, especially those where there are a lot of
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by akkawwakka 6y ago
It’s worth highlighting that a ton of basic science work went into mRNA vaccine development, starting in the early 1990s: - developing the lipid nanoparticles that the mRNA is delivered in, so your cells could actually take it up intact - f
24.
by akkawwakka 6y ago
To correct the quoted assertion... There is little selection pressure on the virus for the spike proteins to evolve and change. SARS-CoV-2 infects human cells just fine using its current spike protein. [1] [1]: https://www.nature
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by akkawwakka 6y ago
Apple has done a nice job of adding a lot of power user functionality to iPadOS, and iOS in general, but discoverability remains a huge challenge. Multitasking is a kludgy set of gestures and dragging things around. There aren’t great affor
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by akkawwakka 6y ago
Automation can also go very far in saving lives. We hear about fatal plane crashes in the news, but don’t really hear about the times that automation and computer systems catch or report a pilot overspending the aircraft, making an unsafe m
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by akkawwakka 6y ago
It’s also subject to frequent corruption and conflicts in them are irritating to solve. +1 to Bazel - though it’s best suited for monorepos where you are building completely from source.
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by akkawwakka 6y ago
I feel more guilty about our usage of non-renewable, GHG-generating power sources like coal or natural gas power plants, and about driving around in my car (even though it’s electric). Aviation accounts for just 2% of CO2 emissions. While
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by akkawwakka 6y ago
Whenever I interview engineers, my main priority, beyond grasping whether they understand the stack they’ll be working with, is gauging how well they can work in an organization of fellow engineers, designers, and product folks to deliver a
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by akkawwakka 6y ago
It’s worth knowing there are very few diseases that can be cured with singular gene edits. Many diseases involve multiple genes, cascades of gene expression, or complex physiological pathways. Oh, and not to mention epigenetics and environm

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