ajryan

10 ms·

31.
by ajryan 9y ago
Suddenly ceasing stimulants does not involve nearly as acute or prolonged a withdrawal as opiates. There's no risk of seizures like there is with benzos. Your dopamine receptors will reset their tolerance much quicker than the 6 months
32.
by ajryan 9y ago
Probably a mobile-only behavior.
33.
by ajryan 9y ago
You wouldn't know who specifically leaked, just that it was either the exec or someone who received the forward.
34.
by ajryan 9y ago
The thing about portrait mode is that it changes the orientation of the subpixels, and a lot of apps don't support anything but horizontal R-G-B. Text antialiasing ends up with halos.
35.
What Is Microsoft SQL Operations Studio (preview)?(docs.microsoft.com)
1 points by ajryan 9y ago|0 comments
36.
by ajryan 9y ago
LINQ to SQL is pretty poor in my opinion, plus it's no longer maintained and bugs aren't fixed[0]. [0]: http://www.aidanjryan.com/blog/2012/08/25/sqlmetal-bug-with-...
37.
by ajryan 9y ago
When was the last time you checked out the open-source lib situation in .NET? I haven't had an issue with this in a long time (check out https://www.nuget.org ). On your second point, isn't that a good thing?
38.
by ajryan 9y ago
They mark the crabs' shells so they aren't bled more than once per season.
39.
by ajryan 9y ago
Will the synthetic enzyme be a direct substitute in the standard LAL enzyme chain? Or will it be an alternative reaction like Lonza's PyroGene?
40.
by ajryan 9y ago
I was a software developer at a company that produces LAL-based endotoxin tests. The best alternative[0] is an enzyme produced recombinantly in insect cells. It triggers an enzymatic reaction similar to LAL's (but more complicated). It
41.
by ajryan 10y ago
I have read that NMDA agonists (DXM, Ketamine, PCP, other arylcyclohexamines) work pretty well for this. Anecdotally, their withdrawal symptoms include tinnitus so I'm not surprised the inverse could be true. It also looks like more sp
42.
by ajryan 10y ago
Isn't that exactly what these studies are doing? The burden isn't to prove that there are no side-effects, just that their rate and severity are sufficiently low.
43.
by ajryan 10y ago
There are many lesser-known psychedlics with scarily-low lethal doses. Bromo-dragonfly and some *-NBOMe compounds are a few that killed people recently. High doses of DOC can cause extreme vasoconstriction in extremeties, resulting in necr
44.
by ajryan 10y ago
In terms of dose-reponse, 100 micrograms of LSD produces effects roughly as strong as 20 milligrams of psilocybin. In terms of subjective perception of the immersion or "pushiness" of the experience, I expect almost all users expe
45.
by ajryan 10y ago
Anyone interested psychedelic users' perspectives on harm reduction, health benefits, and risks should check out http://erowid.org and http://bluelight.org (especially the Psychedelic Drug Discussion subforum).
46.
by ajryan 10y ago
"The brutal may have been moulded by a brutality you cannot exceed. Let guile be your ally." - David Mitchell, Black Swan Green
47.
by ajryan 11y ago
I think it's your opinion on the "ghetto," not twitter, that raises eyebrows.
48.
by ajryan 11y ago
http://blogs.msdn.com/b/oldnewthing/archive/tags/microspeak/
49.
by ajryan 11y ago
Is there anyone with a BGR subpixel-order monitor who has been able to configure Atom (or VS code for that matter) to do the right kind of antialiasing?
50.
by ajryan 12y ago
He said, stroking his Unix beard.
51.
by ajryan 12y ago
Appending ?share=1 to Quora URLs seems to work for me.
52.
by ajryan 12y ago
It was a joke.
53.
by ajryan 12y ago
In ASP.NET vNext, there is no System.Web any more. They have broken the core into separate components, and their source is in the OP link.
54.
by ajryan 13y ago
These are not particular to C#.
55.
by ajryan 13y ago
I call bullshit. "Once a clear design exists, estimation is easy." Nice to have the luxury of putting in free design work in order to produce a fixed bid.
56.
by ajryan 13y ago
I have a guess at the perpetrators: http://nonchalance.com/
57.
by ajryan 13y ago
TypeScript supports this syntax. I believe they are trying to align with ECMAScript 6 as much as possible.
58.
by ajryan 13y ago
Conditional comments have nothing to do with .NET devleopment.
59.
by ajryan 13y ago
Enable keyboard shortcuts and then press "d" to open a new tab full of Compose.
60.
by ajryan 13y ago
So you coined a new word for hyperbole? Cromulent!

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