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a_bonobo
searching PlanetScale…
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151.
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a_bonobo
2y ago
Where will this data be hosted? There's no way I'm leaking even more data into the USA with the way US politics is going. From a different article: >Thundermail isn’t going to use your messages to train AI, it’s not going to in
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a_bonobo
2y ago
Somewhat related, Western Australia's newest billionaire, Laurence Escalante, got rich by running a sweepstakes betting company that operates only in the US. https://www.afr.com/companies/games-and-wagering/es
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a_bonobo
2y ago
While that may be classic Marxist stuff, modern philosophers like Byung-Chul Han give a great twist on the whole thing in a digital age, I should've linked to his works too, especially for the self-optimising HN crowd. Just quoting fro
154.
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a_bonobo
2y ago
https://en.wikipedia.org/wiki/Marx%27s_theory_of_alienation >Karl Marx's theory of alienation describes the separation and estrangement of people from their work, their wider world, their human nature, and thei
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a_bonobo
2y ago
Elicit has a nice new feature where given a research question, it seems to give the question to an LLM with the prompt to improve the question. It's a neat trick. As an example, I gave it 'What is the impact of LLMs on search engi
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a_bonobo
2y ago
They're being a bit intentionally unclear to not attract the lawyers, but the link to Wirecard makes it clear: >Wirecard was a German payment processor and financial services provider that collapsed in 2020 amidst a major accounting
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a_bonobo
2y ago
The author linking to Cockroach Theory at the end is hilarious https://www.investopedia.com/terms/c/cockroach-theory.asp >The cockroach theory refers to a market theory that states when a company reveals bad ne
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a_bonobo
2y ago
There are some direct-to-consumer companies popping up that do this for you for <$300 per sample. New Zealand has Wilderlab, for example, https://www.wilderlab.co.nz/ , the UK has Nature Metrics https://www.nat
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a_bonobo
2y ago
This is a slightly older paper, note that air environmental DNA now has progressed a lot, especially for species mapping. Here's a cool recent paper showing you can extract DNA of local species from spider webs, by sequencing DNA stuck
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a_bonobo
2y ago
The Phantom of Heilbronn! https://en.wikipedia.org/wiki/Phantom_of_Heilbronn
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a_bonobo
2y ago
I've been in academia for 10 years, now 'out in the real world' for 3 years - I agree with your assessment, the only project management strategy academia knows is 'just work longer hours'.
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a_bonobo
2y ago
Lots of USAID-funded research in the US too - there are about a dozen labs researching food security that have been shut down at various US universities as part of the Feed the Future Initiative. Here's one: https://ipmnewsr
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a_bonobo
2y ago
I agree - I've traveled a few times to the US to speak at conferences and every time the border agent tried to entrap me - i.e., tried to get me to confess that I'm being paid for my presentation, which obviously isn't covere
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a_bonobo
2y ago
I agree, it's far more the 'training data' than the model architecture. Given that Windows 11 is such a surveillance/advertisement machine I'm sure they sit on years of user movements MS can use to build a OS-runnin
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a_bonobo
2y ago
Discord works by clicking a button - you get to signup, you fill in your email, bam you're on the Discord channel in your browser. Zero friction, nothing new to learn for the user. IRC on the other hand....
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a_bonobo
2y ago
It's amazing how much they dropped the ball during Covid. They already had everyone and everything in place! But the app is a buggy mess, far worse than Teams, and they just refused to do anything about it. I guess MS-internal politics
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a_bonobo
2y ago
I feel like I'm hitting this now. Just turned 39. I'm very good in my niche, but businesses just want 'answer to question'. I can provide 'answer to question while also making sure the answer-generating process is f
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a_bonobo
2y ago
>Eliminating birthright citizenship would permanently reshape the electorate and weaken U.S. democracy. Importing one of Europe's most illiberal policies would result in a permanent underclass in the U.S., held back by respectabilit
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a_bonobo
2y ago
IME: There's also a weirdly un-technical career path at most places. I haven't seen many mid-sized to larger local companies that have technical career pathways. Most people have to switch to managerial pathways once they hit ~mid
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a_bonobo
2y ago
ONT sells its smallest MinION to regular people, too. But Illumina's and ONT's main market is universities, followed by large hospitals
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a_bonobo
2y ago
There's a market not described here: bioinformatics. The owner of the market, Illumina, already ships their own bespoke hardware chips in servers called DRAGEN for faster analysis of thousands of genomes. Their main market for this pro
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a_bonobo
2y ago
>3. The best software will be open source, since it's easier for LLMs to edit and is way more trustworthy than a random SaaS tool. It will also be way easier to customize to your liking From working in a non-software place, I see th
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a_bonobo
2y ago
some ideas from my own work: - a good LIMS (Laboratory Information Management System) that incorporates bioinformatics results. LIMS come from a pure lab, benchwork background, and rarely support the inclusion of bioinformatics analyses on
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a_bonobo
2y ago
TurnitIn's cheating detection tools have always been garbage - and I say that as an ex-academic who was 'forced' to use those tools extensively (the PDFs submitted by students are only visible in the Turnitin portal with the
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a_bonobo
2y ago
Could you both expand on what you mean? I've built some useful stuff with langchain v1 but gave up on porting it to v2, looked like too much work.
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a_bonobo
2y ago
I used to do this with filenames during bioinformatics analyses. Every step of the analysis was in the filename, so I'd get oyster_results.filteredMAF0.05_filteredHWE0.05_etc._pp_.vcf.gz I stopped doing that once I learned about file s
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a_bonobo
2y ago
Still relevant in DNA space! https://arxiv.org/abs/2402.08777
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a_bonobo
2y ago
Feels like my current place. To use OP's language: if you have shipped and leadership knows about it, but also does not care , you have not shipped. Unfortunately it turns out there's no way to make them care, in my case.
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a_bonobo
2y ago
A very related article: https://link.springer.com/article/10.1007/s11192-024-04936-1 >Nobel laureates cluster together. 696 of the 727 winners of the Nobel Prize in physics, chemistry, medicine, and economics b
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a_bonobo
2y ago
wouldn't surprise me if in a few weeks/months we see this repo packaged up as a for-sale product for the games industry
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