Nesco

6 ms·

31.
by Nesco 1y ago
Uncouplers are particularly useful to make sure your metabolism doesn’t slow down, which makes getting off those drugs when reaching the right body fat percentage without regaining everything way easier
32.
by Nesco 1y ago
Yes, but also BAM15 and mRNA based UCPs overexpression Longer term if it works more research in the domain, including variations of the other well known ones (DNP, XCT-790, mitoCCCP, …) I firmly believe that combined with: - additional prog
33.
by Nesco 1y ago
I am pretty sure uncouplers will make a come back. Just something a little more targeted and safer than good ol’ DNP
34.
by Nesco 1y ago
Yeah, trying to create one right now to try to do some E Coli + Desnoyer’s style flower experiments. I really underestimated the cost
35.
by Nesco 1y ago
Zuck wouldn’t have leaked it on 4chan of all the places
36.
by Nesco 1y ago
To people using org mode, how does it help you more than Markdown? Genuinely curious because I tried at some point and it felt too heavy. Maybe because I am a vim user instead of eMacs?
37.
by Nesco 1y ago
[flagged]
38.
by Nesco 1y ago
I have been working on a symbolic solution to ARC-AGI: https://github.com/nesco/DPS Shapes are converted into trees of paths, and those trees are compressed using a symbolic lookup table A LLM can then use those symbol
39.
by Nesco 1y ago
It’s the French spelling. Saying it’s only to indicate the disappearance of an “s” is reductive
40.
by Nesco 1y ago
You can make the difference between a single wavelength color and a composite color which looks the same, by looking at objects nearby. If they are of one of the composite colors, they should appear in their natural hue Else they will just
41.
by Nesco 1y ago
No, in fact you did! I knew a good friend who lived in Okinawa, and never locked his front door even when going abroad
42.
by Nesco 1y ago
You could grow the nominal wealth of your household by removing the lock
43.
by Nesco 1y ago
Then why do you not have a full open-order policy? It will definitely grow the nominal size of the economy
44.
by Nesco 2y ago
Technical Product Manager / Product Engineer | Paris | Remote OK | Relocation OK Location: Paris, France Remote: Flexible Willing to relocate: Case-by-case Technologies: Product Management, AI/ML (LLMs, NLP, Pytorch), Py
45.
by Nesco 2y ago
From my own experience on a codebase using a lot of custom algorithms on trees and sometimes graphs. There were qualitatively leaps in my day-to-day usage: Claude Sonnet 3.5 and ChatGPT O1 were good for writing slop and debugging simple bug
46.
by Nesco 2y ago
Hey rossng, at which email address could you be contacted?
47.
by Nesco 2y ago
There is no one truly in charge, it's a distributed standard
48.
by Nesco 2y ago
Well, from my very limited comprehension of diffusion models, they apply to fixed length structure, mostly from a continuous space. Maybe a way to make them work with tree structures could be found - that's no trivial task
49.
by Nesco 2y ago
LLMs are autoregressive models. However, the notion of order in ASTs might be nonexistent, especially for parallel branches of computation/control flow. You could attempt to untangle each branch into N sequences, but this would erase c
50.
by Nesco 2y ago
Unfortunately it’s the reason indeed
51.
by Nesco 2y ago
At the very first glance, it's like ARC 1 with some structures serving as contextual data, and more complicated symmetries / topological transformations. Now, I wonder what surprises are to be found in the full dataset. The focus
52.
by Nesco 2y ago
Most of the usual components listed should be standard at some point. The main issue is still that the Web was thought for documents, not apps. The current mess is partially due to OS vendors not agreeing on a standard, cross platform GUI A
53.
by Nesco 2y ago
Modern LRMs do have some tiny degrees of intelligence
54.
Ask HN: Is there a way to increase my agency?
2 points by Nesco 2y ago|1 comments
55.
by Nesco 2y ago
Goodbye HashiCorp...
56.
by Nesco 2y ago
Here is the comparison: Claude Electron app vs Claude Safari PWA Pros: * Can be opened with a customizable shortcut * Takes less RAM (400 MiB < 600 MiB) Cons: * Needs to be downloaded * Weight 150 MiB * Slower to start * Loose language l
57.
by Nesco 2y ago
On macOS, why have an electron app when you can add the webpage to the dock as a PWA?
58.
by Nesco 2y ago
I know a guy who took 1000ug. He told me he had side effects / visual glitches for about an entire week
59.
by Nesco 2y ago
Inside a black hole, the center is in your future , it’s a point in time where geodesics end Time doesn’t seem to end in the universe at large…
60.
by Nesco 2y ago
The universe has no center, a black hole has one. The limits of the visible universe is an horizon on your frame of reference In nerdspeak, the geometries are not the same , one is isotropic the other anisotropic

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