LarsDu88

24 ms·

571.
by LarsDu88 2y ago
Another takeaway, particularly for the HN crowd is that gene therapy both works and still has some major kinks to iron out
572.
by LarsDu88 2y ago
Side note, did not realize the director of mad max made a movie about this with Nick Nolte and Susan Sarandon in the 90s!
573.
by LarsDu88 2y ago
Likely off target insertional mutagenesis
574.
by LarsDu88 2y ago
I should clarify... 7/67 SO FAR Presumably the other children may manifest cancer down the line. Off target insertion was random Also the blood cancer has already killed one of the patients
575.
7/67 Children Receiving Skysona Gene Therapy Develop Blood Cancer(nejm.org)
41 points by LarsDu88 2y ago|54 comments
576.
by LarsDu88 2y ago
A Company called BlueBirdBio was developing a gene therapy treatment for children with a rare neurological disease - Cerebral Adrenoleukodystrophy. It looks like the gene insertion went off target in many cells resulting in blood cancer, wi
577.
by LarsDu88 2y ago
This event may have been the decisive trigger for the Black Death in Europe. Interestingly, Yersenia Pestis is endemic to certain marmot that lives in Mongolia and also happen to be a delicacy when eaten with hot stones (Khorkog; the cheape
578.
by LarsDu88 2y ago
Nobel committee is all in on the AI hype this year!
579.
by LarsDu88 2y ago
Hopfield's work touched so many different fields it's incredible. A rare example of someone who couldn't just stick to one thing, but made an impact in multiple areas.
580.
by LarsDu88 2y ago
I remember seeing a talk by Gary Ruvkun years ago at UC San Diego. He was complaining about how he got rejected from UCSD med school and just about every other med school he applied to. Kudos to him now!
581.
by LarsDu88 2y ago
No. The thing has like 2.5 hours of battery life. You'd have to plan your day around it or get battery extenders.
582.
by LarsDu88 2y ago
Just imagine how fast llama3.2 would be without a computer
583.
by LarsDu88 2y ago
Wow, didn't know you could do that with bevy!
584.
23andMe Is Sinking Fast [Wired](wired.com)
4 points by LarsDu88 2y ago|2 comments
585.
by LarsDu88 2y ago
A recent article on the struggling 18 year old DNA testing company
586.
by LarsDu88 2y ago
You need to look at the casualty figures from the actual battles, not the attrition figures from Napoleon's march back to French allied territory. Russian soldiers under Russian (very often not ethnic russian) generals suffered stagger
587.
by LarsDu88 2y ago
The truth is, the Soviet bloc consistently made lower quality stuff or had much poorer training. There's are a persistent set of myths that both the Soviets and the western arms manufacturers like to perpetuate. The t-34 tank was the g
588.
by LarsDu88 2y ago
Assembly ain't a language. Differs for every chip microarchitecture. Doubt there's many folks who know voyager 1 assembly
589.
by LarsDu88 2y ago
As long as there are tactical nukes that depend on COBOL, COBOL ain't dead. We might all die, but COBOL will sit happy in its steel reinforce nuclear bunker
590.
by LarsDu88 2y ago
The number of papers that use it exceed the number of papers that cite it probably by 100x!
591.
by LarsDu88 2y ago
Perhaps the elimination of the most of the original leadership team along with the board of directors was seen as a red flag. Alternatively, Apple could just invest in Anthropic instead which seems to have had less drama and a lot of the sa
592.
by LarsDu88 2y ago
Terrible piece of legislation. Glad the governor took it down. This is what regulatory capture looks like. Someone commoditized your product, so you make it illegal for them to continue making your stuff free. Might as well make Linux illeg
593.
by LarsDu88 2y ago
Adding to my reading list!
594.
by LarsDu88 2y ago
I was trying to remember where I remember where I heard of this author's name before. Invented the first generative diffusion model in 2015. https://arxiv.org/abs/1503.03585
595.
by LarsDu88 2y ago
For 1 billion frickin dollars
596.
by LarsDu88 2y ago
She'll pop up working with Ilya
597.
by LarsDu88 2y ago
Is it so unimaginable today that a 2x shrinkage is possible?
598.
by LarsDu88 2y ago
Just remember, these are $10000 prototypes. Two more silicon nodes (36 months 2027) and these will be the same size as regular sunglasses
599.
by LarsDu88 2y ago
80lbs is fine for deer. Gotta go higher for armored deer
600.
by LarsDu88 2y ago
During a time of conflict, Russian oligarchs were able to get their money where it was needed -- to their yachts and mistresses.

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