Gatsky

77 ms·

841.
by Gatsky 7y ago
I am 90% sure there will be a useful antiviral therapy available soon, whether it is remdesivir, favipiravir or even chloroquine. This will change the game in humanity's favour. Antivirals are also the only solution which can actually
842.
by Gatsky 7y ago
If there ever was a quintessential example of a “first world problem”, this is it right here.
843.
by Gatsky 7y ago
Don't quite understand how a nuclear bunker is useful. MAD means you would have maybe 30 - 60 minutes to get into them? Plus, if I was attacking the country where the bunkers are located, I would make sure to blow them sky high, since
844.
by Gatsky 7y ago
The bottom line is there isn't any quality data. But there are a lot of clinical trials in patients going on, so there should be something more reliable in 4 weeks or so. The most relevant endpoint at this time is not viral clearance (
845.
by Gatsky 7y ago
https://www.jqknews.com/news/388543-The_novel_coronavirus_pn...
846.
by Gatsky 7y ago
Yes. Apparently the possible utility of chloroquine was discoevered because SLE patients on it in China weren't getting Covid-19 during the outbreak.
847.
by Gatsky 7y ago
Well I was referring to people over 70 as a cohort, we are saying the same thing essentially. On an individual level however, adding an illness with 15% mortality on top of all the other things over 80s can get is a big deal. 80+ year olds
848.
by Gatsky 7y ago
Correct.
849.
by Gatsky 7y ago
The mortality rate is definitely lower than anything being measured. But the lower bound is still high enough that this is very bad, maybe just not 'blight of the eons, scourge of humanity' level. If you are above 70 or have healt
850.
by Gatsky 7y ago
Well satire is a bit strong. But I think the plan seems unwise, due to unvalidated assumptions (especially that immunity will last during a second wave) and the nature of their health system. If an effective treatment emerges, they will als
851.
by Gatsky 7y ago
Also people don't seem to realise, a patient on a ventilator is extremely unwell. They are the most unwell people in the entire hospital. They have 24 hour 1 on 1 nursing, constant invasive monitoring of vital signs, blood tests, X-ray
852.
by Gatsky 7y ago
This is madness. You can’t scale up ICU based ventilatory support to keep up with a pandemic. All resources should be going towards infection control measures, a quick and highly scalable diagnostic test, and antiviral therapy. In that orde
853.
by Gatsky 7y ago
I think you can draw a direct line between the personality of Johnson and adoption of this strategy. Covid19 will unfortunately kill a lot of people. As a silver-lining, it may also kill populism.
854.
by Gatsky 7y ago
This is cool, but if you spend 10 seconds in ICU with a patient needing ventilation you will immediately realise the process can’t be scaled up merely by virtue of having more machines. This is why the only way to avoid the Italian situatio
855.
by Gatsky 7y ago
Under the circumstances, a test better than totally useless is good enough. Unless there is an alternative immediately available. Which there isn’t.
856.
by Gatsky 7y ago
Can anyone provide an example of a country or a company that was not at all prepared for Y2K (there must be one somewhere?), and suffered disastrous consequences? That would seem to be the best way to answer the original question, but I hav
857.
by Gatsky 7y ago
I think progress in physics is going to be on hold for a while. This kind of fundamental scientific inquiry does not proceed in a linear fashion, and there was incredible progress in the last century. Physicists seem to realise this on some
858.
by Gatsky 7y ago
tldr: space lettuce is still lettuce
859.
by Gatsky 7y ago
Could you just clarify how you got this information? Did you witness it directly?
860.
by Gatsky 7y ago
I see, thanks, my original comment was not very well informed.
861.
by Gatsky 7y ago
I find NDAs rather problematic. The main purpose they seem to serve is to hide corporate malfeasance. It would be nice to have a public register for NDAs, such that one could determine how many are being issued by a particular entity (obvio
862.
by Gatsky 7y ago
This is really important, especially in countries where flu season is coming. At the same time, I’ve been reading papers in top journals about various clever technologies to do rapid (ie <60 minutes) detection of pathogens for years. The
863.
by Gatsky 7y ago
This proposal seems ill-founded. The idea that the public sector takes on the risk of early development is a misuse of the word ‘risk’. No funding agency ever thinks of investment in terms of financial risk. The money allocated to an indivi
864.
by Gatsky 7y ago
It’s a good point. However, I doubt anyone will be transporting high value items in autonomous vehicles for quite a while, as insurance will be expensive initially.
865.
by Gatsky 7y ago
This comment is wrong twice.
866.
by Gatsky 7y ago
I have been waiting for this for so long. It really works, well done.
867.
by Gatsky 7y ago
Not sure about your analysis. I think you are just caught in the gap between personal preference and the goals of the healthcare system. You of course see your preferences as paramount, just as does another person who wants hyperthermic the
868.
by Gatsky 7y ago
I love crispy things deeply. However, the crispifying process seems to generate a lot of advanced glycation end products (AGEs). The safety of ingesting large amounts of AGEs is in doubt. https://www.ncbi.nlm.nih.gov/pmc&#x2
869.
by Gatsky 7y ago
I don't think this is as useful as it might seem. Significant respiratory impairment may occur before a drop in oxygen saturation, expecially in the young and healthy. I would not be reassured by an oxygen saturation reading if there a
870.
by Gatsky 7y ago
Big cities in Australia have a lot of gluten free options. There are some interesting therapies on the horizon, basically a pill which contains an enzyme that breaks down the gluten before it can reach the small intestine [1]. I believe Coe

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