Fomite

38 ms·

601.
by Fomite 4y ago
Math is probably the furthest along this particular pathway - which is both a good sign for this being able to work, and also not generalizable.
602.
by Fomite 4y ago
This is one of the reasons that the things I work on most of the time (healthcare-associated infections) are so insidious. At any given institution rates are usually quite low, and infections a rarity. But when you project that up to ever
603.
by Fomite 4y ago
Arxiv, and it's various follow-ons - I think I was one of the first submissions to medRxiv, are excellent as far as they go, but if we take the COVID-19 pandemic as a stress test, they still have a long way to go. Beyond that, their cu
604.
by Fomite 4y ago
This whole post deeply assumes that the authors experience is universal. My comprehension - and grades - went up when I just stopped taking notes in lecture and listened. I read books and remember a lot of what is in them.
605.
by Fomite 4y ago
The amount of money for an NIH R01 non-modular budget hasn't changed since 1999. Which means due to inflation, the average "gold standard" grant budget covers half as much as it used to, roughly. Wherein are you going to fund
606.
by Fomite 4y ago
The problem is rarely corruption by funding in the way you're thinking - Merck going "Hey, can you take another look at those numbers?" The problem is the pressure to get funding by being productive. Negative results are wi
607.
by Fomite 4y ago
"And reviews also vary widely in their conclusions – how they rate papers and whether they recommend editors to accept or reject the paper." This is assumed to be a bug, and not a feature. A lot of this comes from different perspe
608.
by Fomite 4y ago
Having just gotten extensive edits back on two papers of mine, including fixing something that I had overlooked but am glad they didn't, the role of journals is something that I think people underestimate in some fields.
609.
by Fomite 4y ago
"But the emergence of the internet largely nullifies that problem. Wide distribution of scientific information no longer requires scientific publishers." I'm not at all convinced that this is true - people have been saying it
610.
by Fomite 4y ago
Yeah, the West Coast Ag School professor in me in flinching at some of this.
611.
by Fomite 4y ago
Yeah, having read this during a week wherein I have yet to get a full nights sleep was...less than encouraging.
612.
by Fomite 4y ago
cries in Jumbo alum
613.
by Fomite 4y ago
I used to live with an admissions officer - they've got data (and instinct) for "You're probably not going to go here". The same is true for graduate admissions in my experience.
614.
by Fomite 4y ago
Having eaten some absolutely miserable dorm food in my time, I get it.
615.
by Fomite 4y ago
Similarly, at a large land grant university, we talk a lot about improving our rankings, but acknowledge that one of the major metrics (% of students not accepted) is something that's contrary to our mission. It was an open secret wh
616.
by Fomite 4y ago
A library is potentially quite large - essentially, you need a phage that's for that particular organism. Potentially a large number of each species, given that phage and bacteria are in an evolutionary arms race. The trickier part i
617.
by Fomite 4y ago
I'd suggest its much more like, as a Python dev, not being up on the latest applications of Rust for HPC.
618.
by Fomite 4y ago
Also, because I had a sneaking suspicion - Strathdee was an HIV researcher. In fairness, most of infectious disease epidemiology is HIV research. It's entirely reasonable she wouldn't have necessarily heard of a fairly niche thera
619.
by Fomite 4y ago
There's a decent amount of work being done, broadly, in using machine learning to identify resistance mechanisms and work in antibiotic discovery. There's likely applications there for phage as well. But the real problems holding
620.
by Fomite 4y ago
It's not a standard therapy - she had to go to extremely specific specialists, including USAMRID. I've seen her talk multiple times, and am a great admirer of hers, but phage as they are are very much last ditch, bespoke treatment
621.
by Fomite 4y ago
Answering in reverse order: Phages were used in the west prior to the advent of antibiotics. They had a repetitional issue then, because our purification methods weren't always great, so phage preparations had both phage and potent
622.
by Fomite 4y ago
One of the more interesting studies I saw at IDWeek a year or two ago was phage/antibiotic combination therapy, which improves both. Basically, the bacteria being able to out evolve both of them at the same time is substantially redu
623.
by Fomite 4y ago
I say this in another comment, but this has been The Next Big Thing For Infectious Disease since I was an undergrad. I got tenure this year.
624.
by Fomite 4y ago
Phage comes up a lot here - it seems to be on of HN's favorite biology topics. I have a deep and abiding fondness for phage, but they're not quite as awesome as they seem at first glance. From the perspective of an infectious dise
625.
by Fomite 4y ago
What makes you think we don't?
626.
by Fomite 4y ago
It's not really that. Eastern Europe had to continue with phage therapies because they didn't have great access to antibiotics, which have many superior properties. Phage was used in the Western world, but early versions had ser
627.
by Fomite 4y ago
As a biology major who became an epidemiologist, I felt the same way about math - it turns out I'm decent at it, and use it literally every day of my career, but it took halfway through college to have someone approach math in a way th
628.
by Fomite 4y ago
Seriously. This is standard practice for even fairly innocuous human subjects data, and it astonishes me when it's not done elsewhere.
629.
by Fomite 4y ago
I remember rather liking FirstClass.
630.
by Fomite 4y ago
lights a candle for eWorld

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