Fomite

41 ms·

331.
by Fomite 3y ago
There is a whole genre of games my wife lovingly refers to as "job games". They have devoted, albeit niche, followings.
332.
by Fomite 3y ago
I'm one of the researchers on a new disease forecasting project, and I'm bookmarking this because we often use hurricane forecasting as an example of a level of accuracy we aspire to, so this is a really interesting breakdown.
333.
by Fomite 3y ago
13% over 4 years for a novel vaccine against a disease we have been trying and failing to eradicate for the better part of several centuries sounds like a pretty significant step forward to me.
334.
by Fomite 3y ago
Beyond demographics and geography, malaria is just hard . It's not a virus with fairly stable antigenic targets - it's a parasite that readily develops resistance to things. This is indeed huge, even if the effect is only modest
335.
by Fomite 3y ago
And indeed there are a number of trials that show a decrease in all cause mortality (mass childhood administration of azithromycin comes to mind) that we'd miss if we were just looking at already known endpoints.
336.
by Fomite 3y ago
I'm actually surprised we don't have the actual report yet - for large medical conferences and big results like this, there's often a joint Press Release - Conference Presentation - Journal Publication release.
337.
by Fomite 3y ago
Washington State, in particular, has a very broad public records act.
338.
by Fomite 3y ago
There is also an assumption I have found, in both VCs and tech founders, to assume that subject matter experts can either be trivially replicated or hired downstream.
339.
by Fomite 3y ago
A great many papers in my field contain contextual details about the settings the studies were conducted in that would effectively deblind them. That sort of betrays the idea of a pre-print, in my opinion, because they should not depend on
340.
by Fomite 3y ago
I've not seen a major attempt to blind pre-prints, and given you have to remove some identifying information for blinding, I think that would be a tall order.
341.
by Fomite 3y ago
It was considerably faster than a wholesale resubmission to a new journal, and landed the paper in a better home than it would otherwise have found.
342.
by Fomite 3y ago
Based on my experience with vets, a large percentage of the time it ends up living with the vet. Every single one I know has a small menagerie of broken animals.
343.
by Fomite 3y ago
As both a grad student and a postdoc I wrote appeals to rejections for peer review that succeeded.
344.
by Fomite 3y ago
I think the key is that peer review is a promise of an n=2 process. There's no promise that an unreviewed pre-print is going to get two constructive readers. It's also wildly subject to bias - being on a pre-print with a junior,
345.
by Fomite 3y ago
If you make your code available, I'm going to make sure it runs and does what you say.
346.
by Fomite 3y ago
I don’t know a single vet that drives a Mercedes. I know a lot who drove beat up trucks and have a mountain of debt.
347.
by Fomite 3y ago
They also cut costs when they can. Metronidazole for colitis as an example - it’s not the standard of care for humans, but vets use it all the time because it’s wildly cheaper (cents vs $100s for vancomycin or $1000 for Fidaxomicin)
348.
by Fomite 3y ago
That is where some of the frustration does indeed emerge - one vivid example involved refusing a $500 procedure from someone driving a brand new Tesla.
349.
by Fomite 3y ago
Also, as for "Once that cash cow is gone maybe vet school prices will come down to earth." - the source of the rising cost is a combination of two things, neither one of which has anything to do with small animal medicine: 1) The
350.
by Fomite 3y ago
So one of the things that comes up a lot is that it's not actually that correlated with cost. Most vets I know (I also work for a state school, not a for profit company) are very sympathetic toward very large and expensive bills, a
351.
by Fomite 3y ago
I work in a veterinary school, and it's remarkable to see how worn down veterinarians are compared to my colleagues in "people medicine" (and my comparison group are infectious disease folks - they're not exactly a cheer
352.
by Fomite 3y ago
Me too.
353.
by Fomite 3y ago
If future users are markedly different than past users, a p-value isn't going to help you here. It's not unreasonable to assume it's a sample, I just don't think it's worth getting paralyzed by worrying about whethe
354.
by Fomite 3y ago
This is also an assumption of any approach that uses statistical analysis.
355.
by Fomite 3y ago
There's an argument to be made that, so long as your testing fully encompasses all visitors to your site, you aren't sampling the population, you're fully observing it, and statistical significance is irrelevant.
356.
by Fomite 3y ago
I think your first point is compelling, and what I was alluding to - copper bed rails, etc. have pretty modest effect estimates. The costs themselves are on a very similar order of magnitude.
357.
by Fomite 3y ago
Yeah, most of the surfaces I saw them talking about were essentially what you've mentioned - handles, tabletops, etc. I think one of the big problems here is that in this field (which happens to be the one I work in), showing effective
358.
by Fomite 3y ago
I saw a "microbial spears" product at IDWeek years ago. IIRC, Sharklet was more about biofilm formation disruption, rather than killing.
359.
by Fomite 3y ago
For the hospitals that use various antimicrobial surface treatments, keeping them "clean" is indeed essential. But this is already true for most disinfecting agents as well, so addressing it is in the realm of policies already in
360.
by Fomite 3y ago
In the micro-world, there are biofilms, which most certainly fall under the subset of grime.

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