3 ms·

Most likely self-experimenting and community based "trials" are gonna be much more prevalent in the coming years, due to bio hacking opening up. Gonna be even t

by erkkie 12y ago

Most likely self-experimenting and community based "trials" are gonna be much more prevalent in the coming years, due to bio hacking opening up. Gonna be even trickier to regulate and navigate.

ekianjo 12y ago
Oh really ? Is that Science, in a non-controlled environment, no supervision of health care professionals ? I doubt anything like that is going to happen any time soon. Plus, the public does not have access to the synthesis or new materials, and I doubt that people would actually inject themselves with drugs that have never been tested on animals in the first place.
- erkkie 12y ago
  > Oh really ? Is that Science, in a non-controlled environment, no supervision of health care professionals ? I doubt anything like that is going to happen any time soon. You might've misread me as condoning this, not at all, but I think it's inevitably gonna happen and in fact already is, if you dig around a little bit (all kinds of life extension forums out there, not to mention the current nootropics trends). You don't have to agree with or like things to see them coming you know. > Plus, the public does not have access to the synthesis or new materials You wouldn't believe how much is possible to do in a home lab and dna/rna based techniques are becoming more and more accessible as well.
  - ekianjo 12y ago
    > You wouldn't believe how much is possible to do in a home lab and dna/rna based techniques are becoming more and more accessible as well. Sure, but combine the lack of such equipment for most people with the fact that your experiments will have small n size (because of lack of pilot plant scale to do proper large batches of drugs) and the significance of the home trial drops to nil.
    - erkkie 12y ago
      That's to be seen, and it becomes an analytics problem to separate signal from noise more than anything else. For preview google about the current issues around people 3d printing their own dental braces (or prosthetics).
- 1123581321 12y ago
  You're missing the big trend. In addition to the availability of DIY hardware and more ways for patients to find each other and communicate, other developed or developing countries are approving treatments before the FDA. The size of the US market still holds back medical research, but at some point in this century, the size of the "early adopter" markets with sufficient buying power will be big enough that it won't matter. Signed, one American Type 1 diabetic who is tired of the FDA letting us die by keeping the best tools out of our hands. P.S. If an analogy helps you, think about how music piracy ended up giving us Spotify, and how it had to come from Europe to break into the US market, and how it blocked Americans to avoid getting shut down in its early days. Or, think about how Jobs essentially tricked the labels into allowing iTunes. The traditional record label publishing model is analogous to the FDA's drug trial model. The FDA can make any number of arguments about how their method is more rigorous and beneficial, but at some point, newer methods of getting similar results are coming along, and at some point after that, those methods will be backed by a power with the resources and inclination to bring the benefits of rigor to the new methods without resorting to the old methods.
  - zaroth 12y ago
    Just got my son on a CGM last week. The receiver claims a range of 20 ft, but it won't pick him up from our bedroom a wall away. When the receiver fails, you silently lose the hypoglycemia alerts. I've already ordered a pack of Wixels to setup these throughout the house, backyard, and at his preschool: https://github.com/StephenBlackWasAlreadyTaken/wixel-DexDrip https://github.com/StephenBlackWasAlreadyTaken/wixel-DexDrip
    - 1123581321 12y ago
      That's a good solution. I'm getting a Dexcom pretty soon (relatively recently diagnosed.) It's a bit depressing to compare the speed of the Dexcom hacker community to the speed of Dexcom's FDA-approved software releases, but at least we aren't still stuck with Medtronic.
    - deleted 12y ago
      [deleted]

by erkkie 12y ago

Most likely self-experimenting and community based "trials" are gonna be much more prevalent in the coming years, due to bio hacking opening up. Gonna be even trickier to regulate and navigate.

ekianjo 12y ago

Oh really ? Is that Science, in a non-controlled environment, no supervision of health care professionals ? I doubt anything like that is going to happen any time soon. Plus, the public does not have access to the synthesis or new materials, and I doubt that people would actually inject themselves with drugs that have never been tested on animals in the first place.

erkkie 12y ago
> Oh really ? Is that Science, in a non-controlled environment, no supervision of health care professionals ? I doubt anything like that is going to happen any time soon. You might've misread me as condoning this, not at all, but I think it's inevitably gonna happen and in fact already is, if you dig around a little bit (all kinds of life extension forums out there, not to mention the current nootropics trends). You don't have to agree with or like things to see them coming you know. > Plus, the public does not have access to the synthesis or new materials You wouldn't believe how much is possible to do in a home lab and dna/rna based techniques are becoming more and more accessible as well.
- ekianjo 12y ago
  > You wouldn't believe how much is possible to do in a home lab and dna/rna based techniques are becoming more and more accessible as well. Sure, but combine the lack of such equipment for most people with the fact that your experiments will have small n size (because of lack of pilot plant scale to do proper large batches of drugs) and the significance of the home trial drops to nil.
  - erkkie 12y ago
    That's to be seen, and it becomes an analytics problem to separate signal from noise more than anything else. For preview google about the current issues around people 3d printing their own dental braces (or prosthetics).
1123581321 12y ago
You're missing the big trend. In addition to the availability of DIY hardware and more ways for patients to find each other and communicate, other developed or developing countries are approving treatments before the FDA. The size of the US market still holds back medical research, but at some point in this century, the size of the "early adopter" markets with sufficient buying power will be big enough that it won't matter. Signed, one American Type 1 diabetic who is tired of the FDA letting us die by keeping the best tools out of our hands. P.S. If an analogy helps you, think about how music piracy ended up giving us Spotify, and how it had to come from Europe to break into the US market, and how it blocked Americans to avoid getting shut down in its early days. Or, think about how Jobs essentially tricked the labels into allowing iTunes. The traditional record label publishing model is analogous to the FDA's drug trial model. The FDA can make any number of arguments about how their method is more rigorous and beneficial, but at some point, newer methods of getting similar results are coming along, and at some point after that, those methods will be backed by a power with the resources and inclination to bring the benefits of rigor to the new methods without resorting to the old methods.
- zaroth 12y ago
  Just got my son on a CGM last week. The receiver claims a range of 20 ft, but it won't pick him up from our bedroom a wall away. When the receiver fails, you silently lose the hypoglycemia alerts. I've already ordered a pack of Wixels to setup these throughout the house, backyard, and at his preschool: https://github.com/StephenBlackWasAlreadyTaken/wixel-DexDrip https://github.com/StephenBlackWasAlreadyTaken/wixel-DexDrip
  - 1123581321 12y ago
    That's a good solution. I'm getting a Dexcom pretty soon (relatively recently diagnosed.) It's a bit depressing to compare the speed of the Dexcom hacker community to the speed of Dexcom's FDA-approved software releases, but at least we aren't still stuck with Medtronic.
  - deleted 12y ago
    [deleted]