As long as we care about computational latency, the forces that give rise to caching will continue to hold force. The speed of light places a fundamental limit

As long as we care about computational latency, the forces that give rise to caching will continue to hold force. The speed of light places a fundamental limit on the response time from a storage system of a given physical volume, and there are equivalent physical laws on the maximum amount of information that can be stored in that volume. Which technologies we use for our caches and main storages will change, but we're never going to get around the need for caching.