Categorically, yes. But, you're only likely to succeed if you for one, question the fundamental assumptions on which things are built. Anything less is incremen

Categorically, yes. But, you're only likely to succeed if you for one, question the fundamental assumptions on which things are built. Anything less is incremental, or so far down-track in clinical trialing that it wont get funded or wouldn't be sufficient, respectively). Questioning assumptions is fairly straight-forward because so much out there is high quality but seriously questionable bull. Not seeking to cast derisions, just that biology, by its very organic nature, is volatile and often uncooperative. The problem of course is that now we are talking about obtaining deep-domain knowledge, which can take some time, absolute minimum 5 years to read everything, condense and connect-the missing dots. My project, for example, has taken me literally a dozen years, in part, because I hadn't realized I'd started! http://www.reuters.com/article/2012/03/28/us-science-cancer-idUSBRE82R12P20120328 http://www.reuters.com/article/2012/03/28/us-science-cancer-... Accessed 28/04