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This is an interesting news story about one case of a "natural experiment" on human beings that would be quite unethical to perform on a large scale. The study
by tokenadult 13y ago
This is an interesting news story about one case of a "natural experiment" on human beings that would be quite unethical to perform on a large scale. The study of twins reared apart, which was especially active at my alma mater university while I was a student there,[1] took advantage of some other happenstance separations of monozygotic ("identical") twins into more than one family of upbringing to see what effects of home environment on genetically identical young people as they grow up might be.
For behavior genetic studies on fruit flies, direct gene manipulation is considered ethical, and quite harsh environmental tests, tests that would never be considered ethical for mice, are also used. For mice, they can be bred into inbred strains in which every individual for generation after generation is all but identical, and can also be given gene "knockouts" through genetic engineering technology, and the environments can be varied by systematic controlled experiments rather than the haphazardly varying experiences of human beings.
I discuss issues related to this research every week during the school year at my alma mater university with some of the world's leading experts on human behavior genetics.[2] This is a fascinating area of research, and there is always more to learn. Some of the more puzzling questions will probably only get answers as more researchers from varied postgraduate educational background collaborate on conducting continued research.
[1] http://www.hup.harvard.edu/catalog.php?isbn=9780674055469 http://www.hup.harvard.edu/catalog.php?isbn=9780674055469
[2] http://www.psych.umn.edu/research/areas/pib/ http://www.psych.umn.edu/research/areas/pib/
- ghshephard 13y agoI don't suppose anyone knows if there is any ethical review required for experiments on fruit flies? And, follow up question, at what level (higher or lower than fruit flies) are experimenters allowed to proceed experimenting on life forms without an ethics review.
- timr 13y agoI used to work in a fly lab. As far as I know, there are no ethical reviews required for insect studies. I know that animal welfare and ethics reviews are required for mice, rats and other small mammals, but I don't know where a formal line is drawn.
- throwaway0094 13y agoVertebrates.
- tlarkworthy 13y agoAnd octopuses
- Nimi 13y agoI have always wondered: don't adopted children provide another natural experiment, on a much larger scale than the (presumably quite rare) cases of identical twins reared apart? You don't even have to hope there was another child of the same parents who wasn't sent for adoption (although that would certainly help) - simply control for socioeconomic status and everything, and see what the "intervention" of moving a child to an upper middle class family changes. Or not?