4 ms·
Actually that's not true. Generics (at least in Canada but probably true elsewhere as well) only have to give between 85%-120% of the dose of the brand name dru
by haldujai 14y ago
Actually that's not true. Generics (at least in Canada but probably true elsewhere as well) only have to give between 85%-120% of the dose of the brand name drug, this is despite having the same official dosage as printed on the label. The difference comes from preparation, pill coatings, and inactive ingredients.
- kvb 14y agoThat's right. The impact that this has on the quality of the medication is dependent on the dose-response curve. I wouldn't expect this to be a big deal for painkillers, for instance, but it could easily cause noticeable differences elsewhere.
- shubb 14y agoAlso, my friend who works at a pharma factory says brand names have much tighter quality control - more batches are tested with far less tolerance. In addition, some of the details of the chemicals (such as I guess the angles of the molecules) may be different, because the generic manufacturer imperfectly reverse engineers the process used to make the drug. Clinical trials to validate the generic are less strict.