2 ms·
The gamble is basically only a gamble if you wait longer. The graph for pre-35 parents is practically nonexistent. I could live with the 2% chance at 42, but n
by Aeolun 1mo ago
The gamble is basically only a gamble if you wait longer. The graph for pre-35 parents is practically nonexistent.
I could live with the 2% chance at 42, but not with the 15% at 45.
Where the chance is of random abnormalities. Who knows what exciting variant you get.
- jdkoeck 1mo ago15% at 45? You better have a source for that number.
- brikym 1mo agoIt's widely known that maternal age causes more genetic defects and it's especially significant later on. The term "hitting the wall" came from the charts. https://www.medrxiv.org/content/10.1101/2021.04.05.21254264v1.full https://www.medrxiv.org/content/10.1101/2021.04.05.21254264v...
- Aeolun 1mo agoI’m basing this on the vibe from a chart someone showed me when I was in the hospital 8 years ago after my son was born. The point is the chances increase exponentially. Found the list now: Age 20: About 1 in 500 (0.2%) Age 30: About 1 in 270 (0.37%) Age 35: About 1 in 80 (1.25%) Age 40: About 1 in 60 (1.66%) Age 45: About 1 in 20 (5.0%) Which actually kinda refutes me because 1 in 500 is still a lot.
- __turbobrew__ 1mo agoMost chromosome defects (trisomy) can be screened for now. NIPT is effective at 9 weeks pregnant and the technology is only going to get better.