4 ms·

"Mysterious" "Overtraining syndrome" I don't see why it's so mysterious, fatigue accumulates until something tips you over the limit

goda90 2mo ago
Do we know the biological mechanism to cause OTS, though? That would open up avenues for treatment and more precise prevention besides "rest more" (not that that's a bad preventative).
- raverbashing 2mo ago
  Yes, a lot of them. Non exaustive list: - bone microfractures - nervous system depletion - tendon "microlesions" (not so sure about this term though) - immune system blunting due to stress - raised cortisol levels - (possible) nutritional deficiencies given the increased exertion (or just metabolic bottlenecks)
- bbayles 2mo ago
  A lot of it is anorexia by another name. There is a subspecies that involves compulsive exercise. Doing lots of athletics without proper nourishment is a good recipe for low performance and injury.
  - vova_hn2 2mo ago
    > A lot of it is anorexia by another name. Literally my first thought after reading this training log excerpt: > 10/4/2012: I’m really trying to be conscious right now about losing some worthless snack weight… Need to be more diligent, take action, get fucking after it, and restore the body and the mind! "worthless snack weight" sounds very similar to epithets that anorexic people often use.
  - yfontana 2mo ago
    That particular issue is known as RED-S: https://en.wikipedia.org/wiki/Relative_energy_deficiency_in_sport https://en.wikipedia.org/wiki/Relative_energy_deficiency_in_... But over-training can happen even with sufficient nutrition (even if it is less likely, as nutrition is a major part of post-exercise recovery).
    - bbayles 2mo ago
      Also anorexia by another name in many cases, alas.
inigyou 2mo ago
What's fatigue? Is there a fatigue molecule?
- rzzzt 2mo ago
  Lactic acid?
  - perrygeo 2mo ago
    Nope. Lactate and lactic acids are by-products of fatigue, not causal agents. Far from being toxic, elite athletes are even intentionally ingesting lactate as fuel these days.
    - nradov 2mo ago
      Correct. Related to that, accumulation of free hydrogen ions is associated with acute fatigue (although not necessarily related to chronic conditions like OTS). This is why some endurance athletes are now taking sodium bicarbonate supplements.
- raverbashing 2mo ago
  I'd say ask ChatGPT because the list is loooong
- ButlerianJihad 2mo ago
  [flagged]

goda90 2mo ago

Do we know the biological mechanism to cause OTS, though? That would open up avenues for treatment and more precise prevention besides "rest more" (not that that's a bad preventative).

raverbashing 2mo ago
Yes, a lot of them. Non exaustive list: - bone microfractures - nervous system depletion - tendon "microlesions" (not so sure about this term though) - immune system blunting due to stress - raised cortisol levels - (possible) nutritional deficiencies given the increased exertion (or just metabolic bottlenecks)
bbayles 2mo ago
A lot of it is anorexia by another name. There is a subspecies that involves compulsive exercise. Doing lots of athletics without proper nourishment is a good recipe for low performance and injury.
- vova_hn2 2mo ago
  > A lot of it is anorexia by another name. Literally my first thought after reading this training log excerpt: > 10/4/2012: I’m really trying to be conscious right now about losing some worthless snack weight… Need to be more diligent, take action, get fucking after it, and restore the body and the mind! "worthless snack weight" sounds very similar to epithets that anorexic people often use.
- yfontana 2mo ago
  That particular issue is known as RED-S: https://en.wikipedia.org/wiki/Relative_energy_deficiency_in_sport https://en.wikipedia.org/wiki/Relative_energy_deficiency_in_... But over-training can happen even with sufficient nutrition (even if it is less likely, as nutrition is a major part of post-exercise recovery).
  - bbayles 2mo ago
    Also anorexia by another name in many cases, alas.

inigyou 2mo ago

What's fatigue? Is there a fatigue molecule?

rzzzt 2mo ago
Lactic acid?
- perrygeo 2mo ago
  Nope. Lactate and lactic acids are by-products of fatigue, not causal agents. Far from being toxic, elite athletes are even intentionally ingesting lactate as fuel these days.
  - nradov 2mo ago
    Correct. Related to that, accumulation of free hydrogen ions is associated with acute fatigue (although not necessarily related to chronic conditions like OTS). This is why some endurance athletes are now taking sodium bicarbonate supplements.
raverbashing 2mo ago
I'd say ask ChatGPT because the list is loooong
ButlerianJihad 2mo ago
[flagged]